Cellular manufacturing layout design using heuristic clustering algorithm and lpp model

This mathematical model forms machine cells, optimises the costs of unassigned machines and components, and designs the shop floor cell layout to have minimal movement of materials. The complete similarity measure algorithm forms machine cells and part families in a refined form. Later, exceptional elements are eliminated in the optimisation model by using machine duplication and sub-contracting of parts. Then the shop floor layout is designed to have optimised material movements between and within cells. An evaluation of the cell formation algorithm’ performance is done on the benchmark problems of various batch sizes to reveal the process’s capability compared with other similar methods. The data of machining times are acquired and tabulated in a part incidence matrix, which is used as input for the algorithm. The results from the linear programming optimisation model are that costs are saved, machines are duplicated, parts are sub-contracted, and there are inter- and intra-cellular movements. Finally, the output of the inbound facility design is the floor layout, which has machine cell clusters within the optimised floor area.

S RAMESH S ramesh

Effect of culcasia falcifolia on the biogenic amine levels in the brain tissue of pentylenetetrazole induced seizure in mice

In the present study the effect of the ethanol extract of Culcasia falcifolia on the neurotransmitter levels were evaluated. Pentylenetetrazole (PTZ) (60 mg/kg body weight, i. p) was administered to all the groups of mice to induce convulsions. After observing the convulsion, all groups rats were sacrificed, whole brain was dissected out and separated the forebrain. The brain tissue was homogenized and then centrifuged. The aqueous phase was taken for the assay. The reading was obtained using spectroflurimeter. The result of the present study shows that the ethanol extract of Culcasia falcifolia at the dose of 200 and 400 mg/kg body weight significantly increased the level of inhibitory neurotransmitter GABA and also showed significant increase in the levels of dopamine, noradrenalin and serotonin when compared to seizure control group (PTZ treated group) and was almost equivalent to control group. The findings of the study showed that the extract at 200 and 400 mg/kg body weight significantly (p<0.001) increased the levels of GABA, dopamine, serotonin and noradrenaline. The ethanol extract of Culcasia falcifolia exerted antiepileptic activity by decreasing seizure susceptibility to pentylenetetrazole-induced seizure in mice due to restoration of GABA, serotonin, dopamine and noradrenaline concentration levels in mice brain.

Gracelyn Portia Gracelyn portia

The role of indian higher education in economic development

The aim of the paper is to develop Indian economy growth and its impact of upcoming scenario. In the modern world education is becoming the most important resource for economic and social development of countries, improving well-being and individual development of citizens. Education in every sense is one of the fundamental factors of development. No country can achieve sustainable economic development without substantial investment in human capital. Education enriches people's understanding of themselves and world. It improves the quality of their lives and leads to broad social benefits to individuals and society. Education raises people's productivity and creativity and promotes entrepreneurship and technological advances. In addition it plays a very crucial role in securing economic and social progress and improving income distribution. Our higher education institutions serve and enrich society in many ways and their role in modern Ireland is multi-faceted

Dr Gedam Kamalakar Dr gedam kamalakar

Organization behavior - tesco case

The chosen organisation for this research work is Tesco. Founded in 1919, Tesco is one of the most renowned retailing brands operating in the global market (Azad, 2018). It focuses on selling a wide variety of products to its customers at low prices. Since its inception, the organisation has focused on maintaining high efficiency in its internal management. This is done with the help of effective human resource practices and organisational behaviour. The organisation always seeks to maintain good relations with its employees to work hard to attain the organisational objectives. This research work will focus on understanding and analysing the concept of organizational behaviour. This will be done by applying the different concepts and theories of organisational behaviour in reference to Tesco. Concepts such as motivation, leadership, teamwork, change management, and many more will be discussed in this research work.

Zamzam Abdelazim Zamzam abdelazim

Linkage planning of qtl for agronomic and root qualities utilizing ib370 × mas25 (oryza sativa l.)‑f2 population developed under water restricted conditions

Abstract In the existing investigation, experiments were carried out to assess the F2 population’s resultant of crosses between improved Basmati 370 and MAS25 for various agronomical and root traits cultivated under aerobic water conditions. Large variations for grain yield, root length, root dry biomass, root thickness and length/breadth ratio of grain have been displayed in segregating F2 populations. A close examination of phenotypic correlation exhibited that in the F2 population, root length was certainly matched up (r = 0.496) with root thickness. A DNA fingerprinting catalog for the currently studied F2 generation was arranged using 61 polymorphic SSR markers. Composite Interval Mapping (CIM) inspection with WinQTL cartographer version 2.5 disclosed 13 putative QTL (Quantitative Trait Loci), out of which 6 QTL were for root characters 7 QTL for agronomical characters situated on 1, 2, 3, 8 and 10 chromosomes. The QTL documented in the above-said generation, some promising F2 plants were also scrutinized and found in the homozygous or heterozygous state with high repetitions.

Rajesh Yogi Rajesh yogi

Management of solid healthcare wastes in some government healthcare facilities in enugu state, southeast nigeria: a cross-sectional study

Background: The significance of healthcare wastes (HCWs) consists in their hazardous component, which constitutes real danger to public health. In Nigeria, healthcare waste management (HCWM) has remained a problem yet to be properly recognized and so addressed. The study aimed to sensitise health workers and the public on the need for proper management of HCWs, considering the public health implications of not doing so. Methods: The waste management systems of ten healthcare facilities (HCFs) were assessed, using a modification of the WHO rapid assessment tool. In each HCF, segregated wastes were collected daily for ten days and quantified by weighing, using a spring balance. Results: Administratively, the HCWM system was poor in the ten HCFs (40.6%). 70% of them had satisfactory waste segregation, 81%, good waste treatment, and 26.7% adequate transportation methods for waste. None of the HCFs had budget allocation for HCWM, and 90% had inadequate storage facilities. Mean waste generation was 1.81 kg/day, 0.23 kg/patient/day, 0.16 kg/bed/day, and proportion of infectious wastes 16.8%. Correlation between the number of patients and proportion of infectious waste, was positive, strong and significant (r=0.80, p=0.01), and between bed occupancy rate and proportion of infectious waste, was positive too, but weak, and insignificant (r=0.34, p=0.34). Conclusions: In view of the identified weaknesses of the ten HCFs in HCWM, budget allocations for HCWM, improving waste storage facilities and transportation, with strengthening of waste segregation, collection, and treatment, would help to ensure adequate HCWM in the HCFs.

Emmanuel umegbolu

Cytodifferentiation of fundic part of glandular stomach in non descript breed of indian prenatal goat

Though the anatomy and physiology of the adult caprine (Capra hircus L.) stomach have been investigated extensively, the early development of the abomasum has not yet been fully elucidated. The glandular part of abomasum plays an important role in digestion of ingested food by action of gastric juices. Very few studies have been conducted so far regarding histogenesis of goat foetal abomasum in India. In the present study, we have investigated the embryonic and early foetal development of the goat, Capra hircus L. fundic abomasum. We collected 36 developing abomasum of healthy and normal embryos/foeti of goat and assigned them into three group viz. Gr. I (0-50 days of gestation), Gr. II (51-100 days of gestation) and Gr. III (101-150 days of gestation). Small pieces of tissues were processed by routine paraffin. The wall of glandular stomach, the fundic part, was composed of epithelium, pleuripotent blastemic tissue and serosa up to 44 days of gestation. Tunica muscularis became separable at 46 days of gestation. The epithelium was stratified type up to 50 days and gradually changed to pseudo-stratified columnar to simple columnar type from 76 days of gestation. Primary and secondary abomasal folds were observed at 51 and 76 days of gestation, respectively. Gastric pit, the fore runner of gastric gland was reported first at 70 days. The gland became branched tubular type at 145 days. The cells found in the mucosa of the abomasum were surface epithelial cells, chief cells, parietal cells, mucous neck cells and undifferentiated cells. Chief and parietal cell were observed at 76 days and mucous neck cells at 82 days of gestation. Reticular, collagen and elastic fibers came into sight at 38, 76 and 100 days of gestation, respectively. The present study is expected to supplement known data and knowledge regarding histogenesis of goat fetal abomasum and help in diagnosis and treatment of related congenital anomalies.

Varsha Gupta Varsha gupta

Cerebrospinal fluid leakage post-lumbar puncture: a narrative review

Cerebrospinal fluid (CSF) is critical in maintaining brain interstitial fluid balance and providing hydromechanical protection. Lumbar puncture (LP) is a common invasive procedure for obtaining CSF samples to evaluate central nervous system infections and cancers and measure intracranial pressure. While LP is generally considered safe, it is associated with both minor and major complications. Post-LP meningitis occurs in approximately 50% of spinal anesthesia cases and 9% of diagnostic LPs. Additionally, over 70% of diagnostic LPs result in minor bleeding, which can lead to serious outcomes such as spinal epidural hematoma, nerve damage, or paralysis. Significant consequences of LP include headaches and hearing loss; however, other rare complications, such as cerebral herniation and CSF leak syndrome, must be considered carefully. This review synthesizes findings from multiple studies published in PubMed, Google Scholar, and Scopus, highlighting the need for further research on the complications and interventions related to this commonly performed procedure.

Karishma Karishma

Experiences in developing stock market application using php and integrating data on machine learning for data analysis

In the direction of computer globalization and digitization, India is rapidly developing education and information technology. People are taught how to invest in deposits, postal investments, government bonds, gold systems and bonds, and the private sector. The world in which we now live has been completely transformed by technology. The study indicates that there are more than 4 billion active Internet users worldwide, or nearly half of the world's population. Our lives are now faster, easier to manage, and more enjoyable thanks to modern technology. This paper focuses in experiencing and developing a stock application using PHP, React JS, NodeJS and CSS . All the stock data is stored in a MYSQL database. On the other side for developing machine language application python code is used to convert the data into csv format for machine learning algorithms. The investor is presented with a login screen in the python environment where they must enter their user name and password. The stock dashboard shows the investor's current stock holdings, as well as online stocks' their current price, percentage change in stocks, sensex, nifty, bonus, rights, IPO's, annual report etc. statistical methods are used as software modules for the investor, and with a single click of a button, they can compare and contrast their own stocks with online stocks, as well as the trend in the stock market position in order to decide whether to buy, hold, or sell the stocks. Data visualization component is used for comparison of various stocks, and by clicking of a button, stock prediction are displayed whether to hold, buy or sell in future according to the market trend. The trader must log in using their user name and password. The trader will browse the client current market price of all stocks, buying and selling stocks, contract note, client margin, e-off market transactions, ledgers, journals, commission of buying and selling stocks, and so on. In future strategy the stock application programming is converted by a portable mobile application by using python packages like Kivy, PyQt, or even Beeware's Toga library.

Dr.N.R.Ananthanarayanan Dr.n.r.ananthanarayanan

Relationship between culture and gender inequality in india

This paper throws light on the role played by culture and traditions specifically of Hindu religion in legitimising the subordinate position of women in Indian society. Along with presenting a brief account on the status of women from ancient times to contemporary situation, the sex-gender binary has also been explored. How a child after his birth socialised to behave in a certain way on the basis of his/her sex has been noted. This process of socialisation is based on the age old customs and traditions which are discriminatory in nature. The male child is taught to be strong, dominating and aggressive in nature and henceforth assigned laborious work to do for managing the finances of house. On the other hand, female child is taught to be sensitive, loving and caring and therefore assigned to manage household work, child nurturing and motherhood related responsibilities.

Swati sharma

Inclusive education concept, needs, aims and scope

Inclusive education (IE) is a new approach towards educating the children with disability and learning difficulties with that of normal ones within the same classroom. It seeks to address the learning needs of all children with a specific focus on those who are vulnerable to marginalization and exclusion. It implies all learners – with or without disabilities being able to learn together through access to common schools and community educational setting with an appropriate network of support services. This is possible only in flexible education system that includes the needs of different types of learners and adapts itself to meet their needs. Inclusive Education addresses the diverse needs of all learners by reducing barriers inside schools. It is a process of strengthening the capacity of the education system to reach out to all learners. This educational approach provides all students greater opportunities for academic and social achievement. This includes opportunities to participate in the full range of social, recreational, arts, sports, music, day care and afterschool care, extra-curricular, faith based, and all other activities. Inclusive education argues that all children irrespective of the nature and degree of disability should be educated in general schools with non-disabled children. The schools and classrooms operate on the idea that, with right amount of support, students with disabilities can be as competent as students without disabilities.

Kamal Singh Kamal singh

Stability study of liquid paraffin oral emulsion (cremaffin)

Stability studies ensuring the maintenance of product quality, safety and efficacy throughout the shelf life are considered as pre-requisite for the acceptance and approval of any pharmaceutical product. These studies are required to be conducted in a planned way following the guideline issused by ICH, WHO and or other agencies. Importance of various methods followed for stability testing of pharmaceutical products, guideline issued for stability testing and other aspects related to stability of pharmaceutical products have been presented in a present review.

Prachi Barbhaiya Prachi barbhaiya

Central nervous system pseudomass in neurobehçet's syndrome: a rare radiological manifestation and diagnostic challenge

Neuro-Behçet's Syndrome (NBS) is a rare yet potentially severe neurological manifestation of Behçet's disease (BD). Although the condition frequently affects the brainstem, basal ganglia, and diencephalon, [1,2] its occurrence as a mass-like lesion (pseudotumor) is exceedingly uncommon. These tumefactive lesions can resemble neoplastic, infectious, or demyelinating conditions, which often hinders prompt diagnosis and treatment. [1-3] In this report, we discuss a 56-year-old female from Libya with a history of Behçet’s disease, who presented with headaches, visual disturbances, and cognitive slowing. Magnetic Resonance Imaging (MRI) findings indicated a high T2/FLAIR signal in the bilateral basal ganglia and the left cerebellar hemisphere, extending into the middle cerebellar peduncle, accompanied by faint contrast enhancement.

Karishma Karishma

Exploring undergraduate students’ general attitudes towards artificial intelligence: a perspective from vietnam

Undergraduate students’ attitudes towards Artificial Intelligence (AI) in developing countries like Vietnam are rarely explored despite AI’s increasing presence in higher education. This study aims to investigate the attitudes of undergraduate students towards AI. A quantitative research method was used, involving a self-reported survey questionnaire. The sample consisted of 460 undergraduate students (196 males and 264 females) from five public and private universities in Ho Chi Minh City, Vietnam. Data collection took place through a cross-sectional survey in November and December 2023. The General Attitudes Towards Artificial Intelligence Scale (GAAIS), originally developed and validated in English by Schepman and Rodway (2020), was adapted to Vietnamese for this study. The scale comprised 20 items to evaluate students’ attitudes towards AI. Data analysis included descriptive statistics, Cronbach’s alpha coefficient, t-tests, and one-way Analysis of Variance (ANOVA). The results indicated a Cronbach’s Alpha value of 0.705 for the total variable, demonstrating acceptable reliability. Consequently, Vietnamese undergraduate students displayed moderately positive attitudes towards AI. The findings also revealed no significant difference in attitudes based on gender, but there was a notable variation based on the student’s year of study at university.

Le Minh Tien Le minh tien

Psychological health valuation of adults in the present covid-19 situation

The Covid 19 pandemic affects many elements of a person's life negatively. This reduced concern and considered the major problems that people – especially adolescents and young adults – are experiencing. In this regard, the study examined young adults' mental health by looking at the relationship between welfare and several psychological characteristics, such as loneliness, suppression of mind, common anxiety, flexibility, and self-worth. A total of 134 young people (45 men and 89 women) aged 18 to 25 were recruited for the study by purposeful sampling. Information collection Questionnaires are used. The measurement measurements were the Rosenberg personality Scale, UCLA isolation Scale edition 3 and the Coping Capacity Questionnaire. The information was analysed by means of the coefficient of Pearson correlation and a z-test to determine results for various genres. In Pairson's product time correlation test, the above psychological features were linked to well-being. Self-esteem, well-being, resilience and well-being were found to be moderately good. All had a negative association between general anxiety and well being, solitude and wellbeing, and suppression of thought and wellbeing. The results of the Z-test showed no significant differences in psychological variable scores among men and women, meaning that the whole community felt a sense of harmony in difficult times regardless of gender. The gladness of the sample was 7.95 (ranging from 0 to 20), which was very low.

Dr. Amarjeet Singh Dr. amarjeet singh

In vitro microscopic study of calcium oxalate monohydrate crystals growth patterns

The present study aimed to explore the possible morphological features and growth patterns of calcium oxalate monohydrate crystals. The study was carried out on a glass slide under the microscope. The results showed that the calcium oxalate monohydrate crystals may be arborescent, donut, dumbbell, needles, platy, prismatic, rosette, round edges, loose agglomerates and compact aggregates. The study provides detailed information about calcium oxalate monohydrate crystals' morphology and aggregation patterns.

Dr. Salman Ahmed Dr. salman ahmed

Implementation of javanese krama learning in improving students' ability to speak politely at mima 35 nurul ulum ambulu

This study examines Javanese Krama's learning in improving students' ability to speak politely at MIMA 35 Nurul Ulum Ambulu. This research approach is a descriptive qualitative approach, and the type of research used is phenomenology. Data collection techniques using interviews, observation, and documentation. While the data analysis using the model of Miles, Huberman, and Johnny Saldana consists of data condensation, data presentation, and conclusion. The results of this study are 1) Planning for learning the Javanese Krama language to improve the ability of students to speak politely at MIMA 35 Nurul Ulum Ambulu, namely: the teacher prepares a Learning Implementation Plan, prepares to memorize material for the Javanese Krama language vocabulary for students. 2) Implementation of Javanese Krama language learning in improving the ability of students to speak politely at MIMA 35 Nurul Ulum Ambulu, namely: opening, core, and closing activities. Then the habit of using Javanese manners during learning hours and outside the classroom. 3) Evaluation of Javanese Krama language learning in improving the ability of students to speak politely at MIMA 35 Nurul Ulum Ambulu, namely: in the classroom using daily questions, PTS and PAS. Meanwhile, habituation outside of learning hours is by assessing students' speech and manners. 4) The implications of learning Javanese Krama in improving the ability of students to speak politely at MIMA 35 Nurul Ulum Ambulu have a positive impact on students becoming accustomed to using Javanese Krama when communicating with teachers both in attitude and speech.

EDUCARE: Journal of Primary Education Educare: journal of primary education

The anti-depressant activity of fixed oil of phaseolus vulgaris linn. in mice

Phaseolus vulgaris Linn commonly known as red kidney bean, is enriched in protein, carbohydrates and dietary fibres. Beans have nutritional and health benefits and possess antimicrobial, antihyperglycemic, antioxidant and anticancer activity due to bio-active chemical constituents. The following study was carried out to evaluate the anti-depressant activity of Phaseolus vulgaris fixed oil (PVFO) using a forced swim test and tail suspension test in mice. In this study, animals were assigned into four groups (n=7). Group I: Control normal saline (2 mL/Kg), Group II: PVFO I (2 mL/Kg), Group III: PVFO II (4 mL/Kg) and Group IV: standard amitriptyline (10 mg/Kg). The significant results indicated the possible anti-depressant role of Phaseolus vulgaris fixed oil.

Dr. Salman Ahmed Dr. salman ahmed

In-vitro antioxidant and cardio-protective activity of hydro-alcoholic bark extract of terminalia paniculata roxb on isoproterenol induced myocardial infarction in rat’s

The present study was designed to evaluate the In vitro anti-oxidant cardio-protective activity of Hydro alcoholic bark extract of Terminalia paniculata Roxb on Isoproterenol induced Myocardial Infarction in Rat. Wistar albino rats used in this experiment were pretreated with vehicle, HAETP (200,400 and 600 mg/kg, p.o), Vit-C (20 mg/kg, p.o) for 14 days, on 14th and 15th day, Isoproterenol (85 mg/kg, s.c) was injected. After 24 h of last dose of ISO administration, ECG was recorded and serum biomarkers CK-MB, LDH, SGOT and SGPT were estimated. Further antioxidant levels were estimated from the tissue homogenates. Finally histopathological examination of heart was performed. HAETP have shown significant antioxidant activity in DPPH and reducing power methods. Moreover pretreatment with HAETP and Vit C improved ECG pattern and histopathology of heart.

BM V Swamy Bm v swamy

A memetic algorithm for the inventory routing problem

In this article, we study an Inventory Routing Problem with deterministic customer demand in a two-tier supply chain. The supply chain network consists of a supplier using a single vehicle with a given capacity to deliver a single product type to multiple customers. We are interested in population-based algorithms to solve our problem. A Memetic Algorithm (MA) is developed based on the Genetic Algorithm (GA) and Variable Neighborhood Search methods. The proposed meta-heuristics are tested on small and large reference benchmarks. The results of the MA are compared to those of the classical GA and to the optimal solutions in the literature. The comparison shows the efficiency of using MA and its ability to generate high quality solutions in a reasonable computation time.

Mohamed Salim Amri Sakhri Mohamed salim amri sakhri

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