The genus Caesalpinia belongs to the family Caesalpiniaceae and includes 280 species distributed in tropic and subtropical regions of the world. Historically, species of the genus Caesalpinia have been used to treat a wide range of ailments, such as malaria, ascariasis, dysentery, fever, rheumatism, and influenza. Phytochemical works led to the isolation of triterpenoids, diterpenes, flavonoids, steroids and phenolic compounds. Pharmacological studies have shown that the extracts and compounds isolated from this genus exhibited anticancer, anti-inflammatory, anti-malarial, antipyretic, anti-microbial, anti-rheumatic, antiulcer and anti-diabetic activities. Therefore, this review aims to provide a comprehensive overview of the genus Caesalpinia's ethnopharmacology, phytochemistry and pharmacology.

Dr. salman ahmed

This study aims to determine the process of implementing PJOK learning in limited face-to-face learning during the Covid-19 pandemic in class V MIN 2 Palangka Raya City. This type of research is qualitative with case studies. Data collection techniques by observation and interviews. Meanwhile, data analysis uses descriptive data analysis. The results of this study show that:1) planning for sports and health physical education learning during the Covid-19 pandemic in MIN 2 Palangka Raya City: Teachers plan the PJOK class V learning program, develop the Annual Program, carry out Semester Program activities, carry out learning plans in the learning syllabus, distribute effective weeks.2) Implementation of Sports and Health Physical Education learning in MIN 2 Palangka Raya City, namely: development of the Annual Program into the Learning Implementation Plan, carrying out Semester Program activities, implementation of learning plans in the learning syllabus, online teaching, and learning process activities teachers explain teaching materials, apply learning methods.

Educare: journal of primary education

Research Aim: This study investigates the influence of workload and work environment on employee performance, with work stress serving as the mediator Approach: The study employed a quantitative approach using SEM-PLS analysis. The sample included 75 factory workers selected through census sampling conducted from February to June 2023 at PT PSB, a manufacturing firm in Medan, North Sumatra Findings: Findings reveal that workload and work environment positively impact employee performance, mediated by work stress Theoretical Contribution/Originality: This research contributes to the literature by exploring work stress as a mediator in enhancing the understanding of employee performance within the manufacturing sector Policy Implication: Recommendations include PT PSB and similar companies prioritizing plant workers' stress levels, monitoring workload, and fostering a healthy workplace environment Research Limitation: The scope of the study was limited by the number of respondents and the factors considered in assessing employee productivity

L

Urolithiasis, the process of urinary stone formation, entails the presence of compact masses like whewellite, brushite, and urate within the urinary system. Gout, characterized by inflammatory arthritis, emerges from the accumulation of urate (MSUM) crystals. In vitro, examinations focusing on the growth of whewellite (COM), brushite (CHPD), and urate (MSUM) crystals on glass slides present a cost-effective approach for gaining valuable insights into urolithiasis and gout. These studies not only delve into crystal growth patterns but also investigate the potential inhibition of crystal growth through the application of plant infusions, thereby laying the foundation for further extensive research in these domains.

Dr. salman ahmed

Dietary fatty acid composition in broiler influences carcass quality by altering fat deposition and fatty acid profile. Thus, the study was carried out to evaluate the effect of incorporation of rapeseed oil in broiler ration on omega-3 fatty acid concentration of carcass and its traits in broiler chicken. A total of 160 day-old straight run broilers (Vencobb 400) were randomly divided into four treatment groups (G1, G2, G3 and G4) having four replicates of ten chicks each. The basal diets (G1) were prepared to meet BIS (2007) nutrient requirements with palm oil at 1.5, 3, and 4.5 per cent in pre-starter, starter and finisher diets, respectively. The experimental diets were broiler rations prepared with rapeseed oil replacing 25, 50 and 100 per cent of palm oil in G2, G3 and G4 diets, respectively. The diets were fed ad libitum till 6 weeks of age. Six birds from each group were randomly selected and slaughtered on 42nd day to study omega-3 fatty acid concentration of carcass and its characteristics. The crude fat content of breast and thigh muscle was significantly (P<0.05) reduced in the group fed rapeseed oil included diets. However, carcass yield, processing yield and meat to bone ratio of cut up parts was not significantly affected. The colour and pH of breast and thigh muscles were similar among the treatment groups. Omega- 3 fatty acid concentration was significantly (P<0.01) increased in both breast and thigh muscle of G4 group broilers compared to G1 group. Thus, rapeseed oil inclusion in diet significantly increased omega-3 fatty acid concentration and significantly reduced crude fat concentration breast and thigh muscles with no effect on the carcass yield and its quality when included in the diet replacing palm oil at different proportion

Senthil murugan

Adherence to pharmacological therapies are keys to effective treatments in diabetic patients. Previous reviews found that most adherence measurement studies on chronic diseases used a self-reported scale. However, there is no consensus on the best scale to measure adherence in diabetic patients. The purpose of this systematic review was to identify the potential self-reported scale that could be considered for measuring medication adherence in diabetic patients and to provide recommendations for researchers or clinicians to determine appropriate adherence self-reported scales in diabetic patients. This review follows general guidelines in the implementation of systematic reviews. After further review, it was found that 33 studies met all inclusion criteria from 4 databases (Wiley, Science Direct, Scopus, and PubMed). The articles were done by the PRISMA, while the keywords were determined by the PICO method. Most research was conducted in Asia (69.7%) and America (18.2%) on patients with type 2 diabetes (81.3%), patients in hospitals (54.5%), suffering for 1–6 months (54.5%), and using a cross-sectional study design (78.8%). HbA1c clinic data (57.6%) were used in most studies as biological markers of adherence. The measurement scales of medication adherence in diabetic patients are MMAS-8 (57,.5%), MMAS-4 (12.1%), BMQ (9%), MCQ (6%), ARMS (3%), ARMS-D (3%), GMAS (3%), LMAS-14 (3%), and MARS-5 (3%). This review provides information on the different self-reported scales most widely used in diabetic medication adherence research. Various aspects need to be considered before choosing the scale of adherence.

Much ilham novalisa aji wibowo

While today, he was ready to serve 1.4 million meals for schoolchildren, Mr.CC Das, Program Director, Akshaya Patra Foundation from Bangalore also faced the challenges 15-years before its establishment like any other start-up. Similar was the case of Mr.Trilok Gautam, Executive Supervisor, who was working in a remote village called Baran in Rajasthan. On his visit during the mid-day meal preparation, he was inspecting the quality of meal, where women were busy in preparing food. They were preparing bread by rolling the dough, while few were chopping vegetables with utmost hygienic care. Cleaner, safer, quality meal was to be prepared and served for 1,500 poor students. These children earlier used to go hungry from the school. On November 28th 2001, Supreme Court of India gave a verdict and directed the State Government and Union Territories to provide mid-day meal to every child in Government and Government-assisted primary schools. The Right to Food Law emerged as a fundamental right, enforced due to constitutional amendment under Article 32 of the constitution. Hence, every State Government geared up to make the mid-day meal scheme successful in their respective States. The Karnataka government also participated and named this programme as ‘Akshara Dashoha’. Government of Karnataka took the pioneering step to involve NGOs like Akshaya Patra as an important partner of the government to run this innovative mid-day meal scheme under the Public Private Partnership (PPP) Model. Presently, Indian mid-day meal scheme considered as one of the largest mid-day meal programme in the world has a target to reach out nearly 120 million children in the country.

Nitin mali

Background: Formaldehyde is found in different kinds of medicine and industrial products, cigarette smoke, and even numerous vegetables, fruits and seafood that have been illegally preserved with formalin. The water soluble vitamin C is a strong antioxidant that scavenges free radicals and other reactive nitrogen and oxygen species. Even in small amounts, vitamin C can defend nucleic acids, lipids and proteins against oxidative damage. Objectives: the aim of this study is to elucidate the possible changes that take place in the liver of adult male albino rats after intraperitoneal injection of formaldehyde and the possibility of oral vitamin C’s hepatoprotectivity against it. Design: forty-five adult male albino rats were utilized in this work. These animals were allocated randomly into three main groups. Group I (control groups) included 3 subgroups each contained 9 rats : –ve control received no treatment , +ve control which were injected intraperitoneally by 1 ml of distilled water for 10 days and vit.C +ve control group which received a daily dose of ascorbic acid (100mg/kg bw) dissolved in distilled water by gavage for 10 days. Group ΙΙ: contained 9 rats, which were injected intraperitoneally with a daily dose of formaldehyde (10mg/kg BW) for 10 days. Group IΙΙ: contained 9 rats that were injected intraperitoneally with a daily dose of formaldehyde (10mg/kg BW) concomitantly with daily dose of ascorbic acid (100mg/kg BW) by gavage for 10 days. By the end of the experiment, blood samples were collected for biochemical study of ALT (Alanine aminotransferase), AST (Aspartate aminotransferase) and albumin and all animals were anaesthetized by ether inhalation. Liver specimens were dissected out and weighed then subjected to histopathological, immunohistochemistry, and morphometrical examination. Results: Administration of formaldehyde at a dose of 10 mg/kg caused increase in serum activities of ALT and AST ,but regarding albumin ,it remained unaffected .It caused increase in the liver weights and induced several histopathological changes in the liver of adult male albino rats as congested dilated central veins, portal veins and blood sinusoids with increase in the thickness of the wall of the portal vein. Meanwhile, some hepatic lobules showed multiple necrotic foci around central and portal veins. On the other hand, vit.C partially improved the state of oxidative stress as evidenced by iNOS (inducible nitric oxide synthase) immunohistochemistry. It also reduced the degree of hepatic fibrosis as evidenced by Mallory trichrome histochemical staining. Conclusion: Exposure to formaldehyde led to pronounced hepatic damage which is partially limited by vit.C coadministration. Recommendations: Many special precautions should be taken to limit the occupational and environmental exposure and the level of food and water contamination with formaldehyde and use vit.C as a supplement to limit the toxic effects on the liver.

Samar mortada mahmoud

A leader is a person, who influences his followers. The role of leader is often associated with managerial concepts, where a leader leads a team of employees, guides them, motivates them and influences them, in such way that the organisational productivity is honed up. A lot emphasis is on the style of leadership, exhibited by the manager, in honing the productivity of the organisation. According to (Hanvey, 2002; Janus, Kopechanski, Cameron, & Hughes, 2007; Morinaka, 2012; Reio & Fornes, 2011), most parents have dreams and hopes about their children and their lives. But, parents of children with special needs, though have, such dreams and hopes, have a harder time meeting these goals. According to Hanvey (2002), these parents need to devote more time and responsibilities, when it comes to raising a child with special needs, like caring for the child’s physical requirements due to his/ her disability, helping them with their physical and social needs and also help them in developing relationships with the others, so that they get a feeling of belongingness. Families with children having special needs undergo a higher level of stress (Gottfried & McGene, 2013). Families that have children with special needs, go through enormous stress levels, at times even financially stressed are they … (Hanvey, 2002; Moriwaka, 2012). But, Current study focusses on the effective leadership role played by a mother during the Pandemic, which is helping the kids, especially the children with special needs in combating the stress, that they are undergoing. A case of a child, diagnosed with autism(a serious behavioural disorder among young children that now occurs at epidemic rates in developing countries like India), since she turned two and how her mother has been helping her adapt to the new normal of staying home for all her activities and coping up with the increased stress levels.

Nandini

Urolithiasis is a common problem that has been afflicted for centuries and has a high recurrence. This review covers the sixty-four (64) antiurolithiatic plants of the family Fabaceae used in 18 different countries and their historical antiurolithiatc background. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. salman ahmed

Capsicum has been an essential part of the diet for centuries and has been widely used traditionally for ailments. The objective of the present analysis was to determine the diuretic and antidiarrheal potentials of four variations of Capsicum annum L. fruits available in the local market of Karachi, Pakistan. It belongs to the family Solanaceae, and extracts were prepared in 95% ethanol and given in 200 and 400mg/kg doses. The activity correlated with commonly used diuretics and anti-diarrheal, reinforcing its conventional use. To confirm its activity, fruit extracts were evaluated for anti-diarrheal properties in castor-oil-induced diarrhoea. The diuretic activity of the 95% ethanolic extracts of Capsicum annum L. was assessed based on diuresis of 24 hr. collected through a metabolic cage. Urinary excretion of water and electrolytes (Na+ and K+) is significantly increased by the standard diuretic drug furosemide, which is comparable with the extract. The anti-diarrheal effects of 95% ethanolic extracts of Capsicum annum L. were examined by castor oil-induced diarrhoea. All varieties of Capsicum annum L. significantly inhibited the number of defecations.

Dr. salman ahmed

India’s economic system has undergone significant changes in recent years reflecting globalization and changes in national policies. This paper provides a comprehensive analysis of India’s economic growth, focusing on imports and exports. The study explores the key drivers of economic expansion, including trade liberalization, trade agreements, and technological advancement. It also explores the impact of international trade and geopolitical events on business models. It assesses the role of policy measures such as the Goods and Services Tax (GST), the Make in India initiative, and various free trade agreements in generating economic benefits. The paper also assesses the trade balance and its impact on India’s economic stability and growth. The paper concludes with recommendations for improving the market, including diversifying entrepreneurs, investing in infrastructure, and strengthening the domestic economy. The review provides insights to policymakers, businesses, and academics who want to understand and harness India’s economic potential in the global economy

Dr gedam kamalakar

Biological information processing networks rely on allosteric protein switches that dynamically interconvert biological signals. Construction of their artificial analogues is a central goal of synthetic biology and bioengineering. Receptor domain insertion is one of the leading methods for constructing chimeric protein switches. Here we present an in vitro expression-based platform for the analysis of chimeric protein libraries for which traditional cell survival or cytometric high throughput assays are not applicable. We utilise this platform to screen a focused library of chimeras between PQQ-glucose dehydrogenase and calmodulin. Using this approach, we identified 50 chimeras (approximately 23% of the library) that were activated by calmodulin-binding peptides. We analysed performance parameters of the active chimeras and demonstrated that their dynamic range and response times are anticorrelated, pointing to the existence of an inherent thermodynamic trade-off. We show that the structure of the ligand peptide affects both the response and activation kinetics of the biosensors suggesting that the structure of a ligand:receptor complex can influence the chimera's activation pathway. In order to understand the extent of structural changes in the reporter protein induced by the receptor domains, we have analysed one of the chimeric molecules by CD spectroscopy and hydrogen-deuterium exchange mass spectrometry. We concluded that subtle ligand-induced changes in the receptor domain propagated into the GDH domain and affected residues important for substrate and cofactor binding. Finally, we used one of the identified chimeras to construct a two-component rapamycin biosensor and demonstrated that core switch optimisation translated into improved biosensor performance.

Cagla ergun ayva

Social media use is inherently linked to everyday life in the digital world, from professional contexts to leisure time. Prior research focused on antecedents of social media use such as personality traits, age, gender, social skills, and also on broad range of its various effects. Positive effects include extension of friendship network, diminishing anxiety in social interaction, and improving exercise motivation. Problematic social media use and addiction are related to stress, depression, suicidal thoughts, loneliness, and scarce school engagement. Less attention has been paid to the relationship between social media use and well-being. Inconsistent results were obtained; being emphasized either small relationship between time spent using social media and psychological well-being, or absence of significant correlation. Aims: Therefore, we analyzed in this research what degree and how active social media use and self-esteem would lead to subjective well-being. Starting from the necessary distinction between the passive and active social media use, the aim of this study was to analyze the direct and indirect effects of active use and self-esteem on subjective well-being. Method: Based on a cross-sectional design, the survey data was collected from a sample consisted of 653 participants (male = 274; M age = 21.52; SD = 4.33). To verify the hypothesized direct and indirect effects included in the multiple mediation model, a path analysis was performed. Results: The findings showed positive association between active social media use, self-esteem, affective engagement in social media use, sense to belong to online community, number of friends/followers, and subjective well-being, The path analysis revealed excellent fit between proposed mediation model and sample data. Active social media use has directly effect on subjective well-being, and indirectly via sense to belong to online community. Interaction between active social media use and self-esteem significantly predicts subjective well-being. The relationship between affective engagement in social media use and sense to belong to online community is mediated by number of friends or followers on social media platforms. Conclusion: The findings of this study extend the previous research, providing support for the relationship between active social media use and subjective well-being. Keywords: active social media use; number of friends/followers; affective engagement in social media use; sense to belong to online community; subjective well-being; mediation analysis.

Elena stănculescu

The general meaning of a word is the representation of the type from it, in linguistic contexts and certain grammatical forms and this meaning is opposed to the individualized meaning, the separation of a unique item of the type, distinguishable from others. The general meaning seems like a grammatical meaning that is not formally sufficiently marked, but the indefinite articles and the suffixes, in addition to other grammatical meanings, can also express a general meaning in certain contexts. A definite meaning of the noun is generally considered the meaning of the noun in the definite form and indefinite meaning the one of the indefinite noun. But how does the general meaning relate to them? Nouns with general meaning, whether in the indefinite form or in the definite form are meaningfully definite. Both the speaker and the listener know the class that the general noun marks. Despite the formal indefiniteness / definiteness, nouns with a general meaning are semantically definite.

Anglisticum

Network on a chip is a concept in which a single silicon chip is used to implement the com-munication features of large-scale to very large-scale integration systems. For high-end System on Chip de-signs, Network on Chip is considered the best integrated solution. NoC has several advantages over dedicat-ed wiring and buses i.e. increased bandwidth, low latency, less power consumption and scalability. Reduc-tion in the latency (end-to-end latency and network latency), loss probability, energy consumption and re-sponse time are the basic parameters which are considered by the researchers for the optimization of the networks-on-chip topologies. In this paper we review the most popular technologies and also some recent topologies for interconnection networks. We study their performance and summarize their strengths & weakness.

Ashish mulajkar

For thousands of years, lipid based Ayurvedic formulations have been made in India, and the craft has survived down the millennia up to the present time. Some of these deliciously potent phytonutrient preparations are very popular and have sustained the test of time pertaining to their efficacy. Recent researches on the role of phytonutrients in promoting cardio-pulmonary, brain and immune health substantially buttress the philosophy underlying the use of lipids in preparing these emulsions, since a large number of these bioactives are lipophilic. Being lipoidic, they are absorbed through the lacteals in the small intestine, and are then transported through the thoracic duct directly to the heart, bypassing the liver. The formulations utilizing ghee (clarified butter) or sesame oil as the carrier lipid, either while frying the myrobalams or as Anupana (adjuvant), have special significance in modulating bodily immunity, since the immune system is housed in lymphatics which are lipid rich. Amla and lipid based Ayurvedic rasayans (rejuvenating formulations) are a popular and highly palatable group of phytonutraceutical preparations. This group of polyherbal adaptogenic formulations is classified separately from other formulations in Ayurvedic therapeutics. Several of these healthpromoting rasayans are suitable to be consumed by all age-groups in the recommended season and dose. Current research on endothelial and immune cell receptor mediated uptake of lipoidic molecules, together with the knowledge of lipid absorption pathways, lends credence to the usefulness of rasayans in targeting the cardio-pulmonary and immune systems. An attempt has been made in this paper to elucidate the mechanisms underpinning the complex interplay between lipid delivered hydrophobic phyto-molecules, systemic lymphatics and the Immune system.

Sharadendu bali

The main objective of this study is to examine the relationship between globalization, resource conflicts and peace –building in Africa, with particular emphasis on Nigerian’s north-central geo-political zone. The wave of globalization that has swept across the world with its attendant socio-economic and political consequences lies at the heart of this study. The debate that is raging currently amongst intelligentsias, public analysts, and the international community point to the fact that the global system has suffered increasing setbacks occasioned by the impacts of globalization and contestation for scarce natural resource endowments. The changes that have emerged for several decades in both developed and developing nations, with the latter having a greater share of repercussions, have remained largely daunting. The multiplier effects of these changes have resulted in worsening crisis situations, with a fast growth rate of intra-state and/or trans-regionalized networked conflicts, which is why Africa and indeed Nigeria, has become a hotbed for contestations recently. This work adopts a qualitative approach as a method of investigation. This work relies on classic works of experts in the broader discipline of globalization and conflict resolutions, the essence of which is to clearly define ways of ensuring absolute peace in Nigeria’s north-central zone. The paper observes that guaranteeing peace-building requires the adoption of both vertical and horizontal approaches as templates for the realization of peace objectives.

Canice erunke

The result of this study showed that the growth performance of the two varieties of amaranth were greatly reduced, in terms of number of leaves per plant in the saline treated plant exposed to the highest saline concentration compared to the control. Amaranthus cruentus had more number of leaves (6.63) than Amaranthus hybridus (5.67) and Amaranthus hybridus had higher survival rate than Amranthus cruentus(1.83). Although both test plant varieties responded to varying saline concentrations in various ways, both tends to show similar responds. Also, the number of days to germination increases with increased salinity concentrations the two amaranth varieties was both adversely affected by higher saline concentrations, where increased salinity concentrations caused reduction in shoot length Also, the leave breadth was better in the control and the plants with lower amounts of NaCl concentration(0.025 and 0.05), this implies that Amaranthus hybridus and Amaranthus cruenthus tolerate moderate salinity levels, while the plants with higher salinity concentrations (0.075,0.01,0.15) had leave breadth that were small, and eventually died because of high amounts of salt.

Barka peter

Object: In the competitive world of the market economy, every economic unit tries organizing everyday activities. Creating a set of suitable and cost-efficient organizational structures and making competitive products and services, top managers should find the mechanisms of building alternative ways of organizational structures. Methods: This paper presents the traditional and modern management structures, their historical steps, and developed methods. In this footfall of the market economy, companies in developing countries should build their management system’s organizational structure. They should advance a management system, managerial behaviours, and new management styles of developed ones. For this purpose in this research has learned organizational structures of developed companies. The investigation discusses the emergence, formation, and modern appearance of management structures that evaluate organizational structures’ importance in enterprises and companies’ activities, using vivid examples. Findings: Then, it has shown some forms of developed organizational structures of companies with the assessment of their highest role in management. In the conclusions and recommendations, we offer our approaches to solving existing organizational problems using the historical period of development to this day.

Ikboljon odashev mashrabjonovich