Les études sur la langue française la présente souvent dans des situations où elle est en contact avec les langues africaines. Elle co-apparait avec les langues africaines dans les discours romanesques. Cette co-apparition n’est pas sans conséquences pour les deux langues en contact. Certains linguistes, surtout les sociolinguistes et les didacticiens, parlent d’insécurité linguistique. Ils la lient à toutes les situations linguistiques où deux langues entrent en contact. Ngamassu (2007, p.94) dit dans ce sens que « toute situation de contact des langues est source d’insécurité linguistique, car aucun locuteur/scripteur ne peut maîtriser toutes les variétés ou niveaux d’une langue ». Cette affirmation restreint l’insécurité au locuteur ou au scripteur. Les linguistes ignorent souvent l’impact négatif du contact des langues et s’intéressent à ses conséquences positives. Cet article a porté sur les manifestations de l’insécurité linguistique dans la prose romanesque de Kourouma et Badaman. Il a permis de voir que l’usage des langues maternelles dans le français constituait une menace de disparition et d’abâtardissement de la langue française.
Ecbalium elaterium has a very violent effect on the body and has little use in modern herbalism. Little is known about the acute and chronic toxicities of ecbalium elaterium in human. This study aims to determine the acute toxicity (LD50) of fruit extract and another aerial part extract of the ecballium elaterium in experimental animals. Thus, male albino mice were divided into different groups each group consists of six mice receiving 40, 46, 52, 61, and 69 mg/kg of fruit extract of ecballium elaterium, respectively. Other groups were given 1000, 1412, 1995, 2818, and 3981 mg/kg of the areal part of ecballium elaterium extract, respectively. The LD50 in both treatments was determined by using the Spearman-Karber method. The LD50 of the fruit and aerial parts of ecballium were 55 mg/kg and 2112.5 mg/kg, respectively. The present findings showed significant weight loss after one month of treatment with 1400 mg/kg and 40 mg/Kg of fruit and aerial part extracts, respectively. The results indicated that the fruit extract is highly toxic as compared to the extract of the aerial parts.
Mediterranean journal of pharmacy and pharmaceutical sciences
2-Azetidinone shows biological activities like anti-bacterial, anti-microbial activity, anti-tubercular activity, and anti-cancer activity. 2-azetdinone derivatives were synthesized by simple procedures. The first step is synthesis of benzohydrazide through nucleophilic substitution reaction between methyl benzoate and hydrazine hydrate. The above formed compound is then treated with substituted aromatic aldehydes in the presence of catalytic amount of concentrated hydrochloric acid with stirring for one hour to give benzohydrazone which results in the formation of Schiff bases.Schiff bases undergone cyclisation in the presence of chloroacetylchloride and diethylenediamine by using ethanol as a solvent upon stirring for 4 hour’s yielded 2-azetidinone derivatives. The in-silico anti-leukemic activity was determined by using the computational tools i.e. “PASS Online”, “AutoDock4.2” and “ADMET” properties by online software’s. Among these six derivatives compounds (AZT-6) was shown more activity when compared with the other five compounds.
Cervical and ovarian cancers contribute significantly to female morbidity and mortality worldwide. The current standard of treatment, including surgical removal, radiation therapy, and chemotherapy, offers poor outcomes. There are many side effects to traditional chemotherapeutic agents and treatment-resistant types, and often, the immune response is depressed. As a result, conventional approaches have evolved to include new alternative remedies, such as natural compounds. Aquatic species provide a rich supply of possible drugs. The potential anti-cancer peptides are less toxic to normal cells and can attenuate multiple drug resistance by providing a productive treatment approach. The physiological effects of marine peptides are described in this review, which focuses on various pathways, such as apoptosis, microtubule balance disturbances, suppression of angiogenesis, cell migration/invasion, and cell viability. The review also highlights the potential role of marine peptides as safe and efficacious therapeutic agents for treating cervical and ovarian cancers.
Sulfur dioxide, a noxious air pollutant, can cause health and environmental effects, and its emissions should be controlled. Nonthermal plasma is one of the most effective technologies in this area. This study evaluated the efficiency of a packed-bed plasma reactor (PBR) and in-plasma catalysis (IPC) in SO2 removal process which were finally optimized and modeled by the use of the central composite design (CCD) approach. In this study, SO2 was diluted in zero air, and the NiCeMgAl catalyst was selected as the catalyst part of the IPC. The effect of three main factors and their interaction were studied. ANOVA results revealed that the best models for SO2 removal efficiency and energy yielding were the reduced cubic models. According to the results, both PBR and IPC reactors were significantly energy efficient compared with the nonpacked plasma reactor and had high SO2 removal efficiency which was at least twice larger than that of the nonpacked one. Based on the results, the efficiency of IPC was better than in PBR, but its performance decreased over time. However, the PBR had relatively high SO2 removal efficiency and energy efficiency compared to the nonpacked reactor, and its performance remained constant over the studied time. In optimization, the maximum SO2 removal efficiency and energy efficiency were 80.69% and 1.04 gr/kWh, respectively (at 1250 ppm, 2.5 L/min, and 18 kV as the optimum condition) obtained by the IPC system which were 1.5 and 1.24 times greater than PBR, respectively. Finally, the model’s predictions showed good agreement with the experiments.
Introduction: The university experience often brings various personal and academic challenges that can negatively impact students’ mental health. This research aimed to evaluate the effect of a mindfulness program on stress, anxiety, depression, sleep quality, social support, and life satisfaction among university students. Methods: A quasi-experimental study was conducted with 128 participants, divided into experimental and waiting list control groups. The experimental group participated in a mindfulness meditation program consisting of 12 weekly sessions. Pre-test and post-test measurements were performed using the Perceived Stress Scale (PSS-10), the Zung Self-Rating Anxiety Scale (SAS), the Zung Self-Rating Depression Scale (SDS), the Pittsburgh Sleep Quality Index (PSQI), the Medical Outcomes Study Social Support Survey (MOS-SS), and the Satisfaction with Life Scale (SWLS) to assess the variables. Results: The experimental group showed statistically significant differences between the study phases and the groups after the intervention for all the variables examined (p < 0.05). The effect sizes calculated using the HC3 model were stress (η2 = 0.376), anxiety (η2 = 0.538), depression (η2 = 0.091), sleep quality (η2 = 0.306), social support (η2 = 0.704), and life satisfaction (η2 = 0.510). The mindfulness program was shown to be effective in reducing levels of stress, anxiety, and depression while also improving sleep quality, social support, and life satisfaction in college students. Conclusion: These findings indicate that mindfulness meditation may be valuable for enhancing psychological well-being in educational settings.
Adenine causes damage to kidney structure and functions; thus, it affects its excretory functions and metabolism. Solanum macrocarpon is a vegetable commonly eaten in Nigeria. This study was designed to examine the potential anti- nephrotoxicity effects of Solanum macrocarpon leaves extract on adenine-induced nephrotoxicity in male Wistar rats. A total of thirty (30) rats were obtained from the Department of Animal Science, University of Ibadan, and were divided into six (6) groups with five (5) animals in each group. The animals were fed with standard feed and drinking water, and treated as follows:, Group 1: distilled water, Group 2: 1000 mg/kg of Adenine only, Group 3: Adenine + 1050 mg/kg ethanol extract of Solanum macrocarpon, Group 4: Adenine + 1050 mg/kg diethyl ether extract of Solanum macrocarpon, Group 5: 1050mg/kg ethanol extract of Solanum macrocarpon and Group 6: 1050 mg/kg diethyl ether extract of Solanum macrocarpon. Biochemical parameters such as creatine, urea, uric acid, sodium, potassium, phosphorus, bicarbonate, and superoxide dismutase were determined in the plasma using a Spectrophotometer. Data were analyzed using one–way analysis of variance (ANOVA) followed by Tukey’s test, with P < 0.05 considered significant. The results indicated a significant increase (P ˂ 0.0) in SOD, creatinine, potassium, sodium, phosphorus urea and uric acid in the group treated with adenine alone, with a significant decrease of 33.3% in bicarbonate when compared with the control. Histopathological examination showed nephritis, through congestion, hypertrophied glomeruli, vacuolization of the endothelial cells lining the glomerular tuft, and interstitial nephritis by adenine treatment. The elevated creatine, SOD, potassium, sodium, phosphorus, urea and uric acid were significantly improved. In the groups treated with Solanum macrocarpon alcoholic extracts. In conclusion, Solanum macrocarpon extracts mitigated the nephrotoxicity caused by adenine.
Overpopulation is a global problem which affects almost everyone in the globe by reducing the available natural resources in the existence. An epidemiological survey was conducted with the aim to assess the people’s response towards overpopulation and its harms to them. The study was conducted based upon descriptive survey design using interview method. The study comprises 80 people residing in selected rural area. The data was collected based on purposive sampling using checklist. The study reveals that most of the people are residing by doing unskilled work due to unemployment with poor living standard.
The recent boom in Android mobile device usage has caused a shift in the information technology and has affected the way how information and data are stored, shared among the mobile users. The advent of social networking applications also demands the availability of resources that can be shared among the authentic users. This paper reviews and compares the available techniques and solutions for detecting Unexpected Permission Authorization to Mobile Apps. It is observed that malware for the android system is also growing significantly, current solutions for detecting malware on smartphones are still ineffective.
Computer-assisted disease diagnosis is cost-effective and time-saving, increasing accuracy and reducing the need for an additional workforce in medical decision-making. In our prior research, we trained, tested, and compared the accuracies of nine optimizable classification models to diagnose and predict eight anaemia types from Complete Blood Count (CBC) data. This study aimed to improve these classification models by oversampling the original imbalanced dataset with four algorithms related to the Synthetic Minority Over-sampling Technique (SMOTE). The results showed that the validation accuracy increased from 99.22% (Ensemble model) to 99.57% (Tree model), and most importantly, the False Discovery Rate (FDR) for the anaemia type with the highest FDR decreased from 23.1% to 1.5%.
In this paper, investigations are made to analyze the human body temperature during wound healing process due to surgery. Wound is considered after the skin graft. Skin graft is a technique used in plastic surgery. Skin is the first line of defense between the human and environment, it is very susceptible to damage. Internal body or core temperature (Tb) is one of the clinical vital signs along with pulse and respiratory rates. Any disturbance in body temperature will drive complexities in wound healing process. These studies are important in the mechanism of establishing the limits of thermal regulation of human body during the healing process in different situations and conditions. The Finite element method is used to analyze tissues temperature for normal tissues (donor site) and abnormal tissues (tissues after surgery). Appropriate boundary conditions have been framed. Numerical results are obtained using Crank Nicolson Method.
The research into plant is used to search for new agents with pharmacological activities. This study seeks to evaluate the effects of the palm leaf methanolic extract against nephrotoxicity, hepatotoxicity, and weight loss induced by chemotherapeutic drug doxorubicin in a rat’s model. Five groups of rats (n= 4 in each group) were treated with or without doxorubicin (3.0 mg/kg/day, ip) and with palm leaf methanolic extract (400 mg/kg/day or 1200 mg/kg/day, po), followed by evaluation of renal and hepatic biochemical markers. The findings obtained indicated that palm leaf methanolic extract exerts protective effects against doxorubicin-induced nephrotoxicity and hepatotoxicity. Doxorubicin significantly elevated renal function markers, namely creatinine, uric acid and urea, however, these biomarkers remained within normal levels after treatment with palm leaf methanolic extract (400 mg/kg/day) as compared to the control group. Treating the rats with doxorubicin and palm leaf methanolic extract at doses 400 mg/kg/day and 1200 mg/kg/day, counteracts the doxorubicin-induced elevation of serum creatinine and uric acid compared to the doxorubicin group. Doxorubicin also significantly increased hepatic function tests namely alanine and aspartate aminotransferase, gamma-glutamyl transferase, and bilirubin as compared to the control group. In addition, treating the rats with palm leaf methanolic extract doses and doxorubicin caused a significant decrease in the serum levels of hepatic markers compared to the doxorubicin group. Doxorubicin treatment resulted in a weight loss of 34.1%, the weight loss caused by doxorubicin was prevented by treating the rats with the extract at 1200 mg/kg/day as compared to their baseline body weight. Thus, the results of the current study suggest that the active constituents present in the palm leaf methanolic extract have a protective effect against hepatotoxicity, nephrotoxicity and weight loss-induced by doxorubicin.
Mediterranean journal of pharmacy and pharmaceutical sciences
Dynamic capability has been used as the basis for organizations to build digital transformation to stay competitive in the market. This literature review aims to determine the significance of dynamic capability and digital transformation in family businesses. Using a systematic literature review methodology and utilizing the Dimensions database, three articles that met the criteria and fulfilled the goal of the review were selected. The findings indicate that family businesses have important dynamic capabilities that can aid their survival and expansion through digital transformation. Therefore, family business owners and managers should be able to identify and effectively use their dynamic capabilities to implement digital transformation in their business operations.
World Health Organization (WHO) estimation disclosed over 116 million girls (3.4%) area unit stricken by PCOS worldwide. The predisposing risk factors embrace genetic science, system, lifestyle/environment, fatness that contributes to the event of PCOS. it's calculable that between 5 to ten % of U.S. girls of childbearing age have PCOS. that is regarding five million girls, which makes the condition one among the foremost common secretion endocrine disorders among girls of generative age. A study to assess the prevalence of PCOS among adolescent women at hand-picked setting, Chennai. Objective: to assess the prevalence of PCOS among adolescent women. Methodology: A non-experimental descriptive analysis style was adopted during this study. The non-probability convenient sampling technique was accustomed choose the sample size of two hundred adolescent Girls. The assessment of the prevalence of PCOS was administrated employing a self-reported check list through a Googletype. A survey link was sent to the respondents, via email and WhatsApp& teams. knowledge was analyzed by descriptive and inferential statistics. Result: our Majority (36.5%) of the samples had gentle & moderate PCOS symptoms and twenty-sevenths had severe symptoms. relating to physical activity, the bulk (38%) of the samples had gentle physical activity, thirty-fourth had moderate physical activity and twenty-eighth had severe activity. There was a direct correlation between PCOS symptoms and Physical activity. There was a statistically vital relationship between PCOS symptoms with age, religion, academic standing, dietary habits, previous information, supply of data, the cycle of emission and BMI and there was a statistically vital relationship between physical activity with age, Religion, academic standing, monthly family financial gain, age at the time of start, previous information, supply of data, variety of family, Cycleof emission & BMI. Conclusion: PCOS among adolescents is a rising problem that wants careful assessment, timely intervention, and appropriate treatment. Diagnosis of PCOS in adolescence remains a challenge attributable to overlapping symptoms of PCOS with traditional time of life changes in adolescents. life-style modifications for weight reduction and dietary modifications and psychological content plays vital role in these young ladies for preventing long run complications. Keywords: Poly cystic ovarian syndrome (PCOS), Prevalence, PCOS symptoms, Physical activity, Adolescent Girls.
Scientific research is an extremely important element in higher education. Nearly all undergraduate students at the university are required to take research courses in the formation process. Therefore, the current paper aims to explore Vietnamese undergraduate students’ attitudes towards research. To measure attitudes towards research, the study used Papanastasiou’s Revised Attitude Towards Research (R-ATR) scale (2014). This psychometric proprieties scale consisted of 13 items with three factors: research usefulness (4 items), research anxiety (5 items), and positive research predispositions (4 items). Data were collected by a questionnaire survey on a convenient sample of 520 undergraduate students from six universities in Vietnam. Descriptive and inferential statistics were used to analyze the data. The findings indicated that the students’ attitudes were high in the factor of research usefulness and positive research predispositions. However, in the factor of anxiety, the attitudes were moderate. In addition, the public undergraduate students had significantly more positive attitudes towards research than the private undergraduate students. Similarly significant results were found for gender, year of study, and research experience.
Education is power. It constitutes the foundation of all the multidimensional socio-economic development of a country. In the present context, we need manpower or human capital for generating the growth and development in a country. The Government of India has taken several many initiatives for promoting education at all the stages i.e. Primary, Secondary and Higher. But still, we find such issues as a high dropout rate at all the stages of education, rural-urban disparity, gender disparity, interstate variations pose as some of the problems that impedes the development of human resources in our country. Even the work participation rate in India indicates the necessity of proper planning of skill training and employment opportunity. Most interestingly, the existing general and conventional higher educational institutions have not effectively been able to cope with the contemporary challenges and changes with the result that the nature of curriculum which is by and large in place tends to create only degree inflation in our country. So, we need such institutes and institutional arrangement that can cater to the contemporary challenges so as to upgrade the quality of education as well as to provide need based educational programmes that can develop human power in the society. Effective or quality education especially at higher level can play a vital role in bringing around multifaceted human resource development, enabling the learner’s absorption in the job market and selfemployment. This paper will discuss how the accessibility of education can be promoted to all through a convenient mode of education system and how the disparities in education can be minimized, and also focus on the various strategies for strengthening higher education system in the country.
Vigna aconitifolia (Jacq.) Marechal. (Papilionaceae) is a medicinally important plant used for treating different diseases, especially dermatological disorders. Alkaloids, phenols, flavonoids, and phytic acid have been reported in this plant. Vigna aconitifolia also exhibits antioxidant, antidiabetic, and hypocholesterolemic activities. The present review attempts to compile all the previous data based on its medicinal uses, phytochemistry and pharmacology reported in the earlier articles.
The study examined the impact of school enrolment growth on the carrying capacity of universities in Imo State, Nigeria. Three research questions and hypotheses guided the study. The study adopted the descriptive survey design with a population of 2,929 academic staff in the two public universities in Imo State. The sample size was 352 representing 12% of the population drawn using stratified random sampling technique. An instrument titled ‘School Enrolment Growth and Carrying Capacity of Universities Questionnaire (SEGCCUQ)’, structured on the 4 point scale, validated by experts and with reliability index of 0.84 was used for data generation. Mean and standard deviation were used to answer the research questions while z-test was used to test the hypotheses at 0.05 alpha level. Among others, the study revealed that factors such as natural increase of population, influx of migrants, enforcement of compulsory education, raising of school-leaving age, increased enrolment of girls and so on influence school enrolment growth that bear on the carrying capacity of universities. It was recommended among others that the factors should help the governments and institutions to forecast enrollment more effectively likewise permit them to make adjustments to meet current or future enrolment.
Urolithiasis is a common worldwide problem with high recurrence. This review covers thirty-six (36) families starting from alphabet M to R. It includes Rubiaceae (17); Phyllanthaceae and Rutaceae (09); Polygonaceae (08); Pinaceae and Piperaceae (06); Menispermaceae, Myrtaceae, Oleaceae, Oxalidaceae, Plantaginaceae and Ranunculaceae (05); Moraceae and Musaceae (04); Meliaceae, Orchidaceae and Rhamnaceae (03); Moringaceae, Onagraceae, Papaveraceae, Pedaliaceae, and Polygalaceae (02); Magnoliaceae, Malpighiaceae, Molluginaceae, Myoporaceae, Nyctaginaceae, Paeoniaceae, Parmeliaceae, Parnassiaceae, Periplocaceae, Platanaceae, Polypodiaceae, Portulacaceae, Primulaceae and Punicaceae (01) plant used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.
Sexuality is a subject to be discussed without shying-away. This essay, discusses about how sexuality of a certain minority people in India and across borders, are being perceived by people in various countries and the consequences faced by the people whose sexuality seems deviant i.e. the sexual minorities from the majority . This essay provides illustrations in the form of research done by various sources that provides such evidences that paint a different picture of the sexual minorities viz. Lesbian, Gay, Bisexual, Transgender, Intersex and Queer (LGBTIQ) people in India and across the world aiming at eliminating the prejudice against them.