Bank sector crisis across the globe is largely blamed on the joint effort of bank liquidity and bank credit risks. And so, the twin concepts of liquidity and credit risks have come under keen academic scrutiny, especially in investment finance. Contributing to the extant literature on these developments, secondary data were obtained from the websites of nine banks in Ghana, spanning 2008 to 2018, to determine how liquidity and credit risks separately and interactively impact bank stability in Ghana. Analysis of data was done using a panel regression through the fixed effects model after running the Hausman Test. The study confirms an inverse liquidity risk-bank stability relationship, emphasising the need to channel idle funds into interest-earning securities to consolidate bank profits. Although a further revelation suggests an insignificant negative relationship between credit risk and bank stability, it re-echoes the need to implement policy recommendations made by the Banks and Specialised Deposit-Taking Institutions’ ACT 2016 (ACT 930), section 62 of Ghana, on the threshold to lend funds to clients. The bank-size-stability relationship was positive. Increasing bank size through establishing more branches nationwide is encouraged but to a precautionary level since banks tend to suffer diseconomies of large scale operations due to unregulated expansion. There is the need to observe the Basel III provisions on maintenance of a 30-day optimum liquidity threshold of up to 100% and above. Besides, banks should tighten up their credit requirements and also ensure loan repayments history is monitored to benefit clients who are in good standing.

Juabin matey

Social competence is often seen as a desirable trait during adolescence as it is considered as a protective factor in resilient individuals. It promotes personal and interpersonal effectiveness by enhancing skills needed for dealing with environmental challenges in daily life situations. Poor social competence has been associated with a number of psychosocial troubles during adolescence, including mental disorders, emotional and behavioral problems. Of the many skill building programs used to enhance adolescent social competence, Life Skills Education and Training have been significant ones. The present study investigates the utility of life skills training in enhancing social competency during adolescence. A pre- and post-test experimental design was used in the study to analyze the stated objectives. Adolescent Social Competency Scale was used to select the study sample. 160 adolescent students (mean age=16.44) who scored low on social competence participated in the study. These were randomly divided into the experimental and control group (n=80), consisting of equal number of male and female adolescents (n=40). Participants in the experimental group were trained on six of the ten core life skills, based on the module prepared by the researcher. The training lasted for 10 sessions following which post-test assessments were done. Data obtained was analyzed using descriptive statistics like mean, standard deviation and inferential statistics including independent sample t-test and repeated measures of ANOVA. The results of the study indicate a significant effect of life skills training in enhancing adolescent social competence, irrespective of gender.

Hita claudia rao

The aim of the present study was to explore the nature of visual representations in biology textbooks across five educational boards across Asia through quantitative and qualitative content analysis. Descriptive statistics was used during the quantitative analysis. Qualitative content analysis involved a deductive approach where visuals in these textbooks were examined and categorized into different categories based on a newly developed typology and taxonomy of visual representation (coding scheme). Under this newly developed typology and taxonomy (coding scheme), visuals in biology textbooks can be categorized into 19 different categories. The findings of the study summarized the characteristics of visual representation usage in these textbooks in terms of their prevalence, distributional differences and trends. Through this study, a new perspective on the taxonomy and classification of visual representations, especially for biology textbooks, has been proposed. Biology teachers and textbook authors can gain insights through the findings of the study. Subjects: General Science; Biology; Secondary Education

Dr t premalatha

Introduction: Traumatic brain injury is caused by an external physical force which may result in altered level of consciousness with or without impairment of cognitive and physical functions in individuals. It is neither congenital nor degenerative in nature. The impairments can be permanent with partial or total functional disabilities or psychosocial maladjustment. The Intensive rehabilitation with multiple health disciplinary teams can improve a certain extent of physical and cognitive aspects of brain injury patients. Case Report: In this case report we are presenting a 19 year old boy diagnosed as diffuse axonal injury with Glasgow coma scale (GCS ) Score of 4/15 (E1M2V1) at the time of incident has come to our department after 8 months with no head control, no cognitive and no voluntary attempts to do functional activity. The main objective of management is to improve mobility, communication, perception and cognitive functions with minimum period of time by working as a health team. Conclusion: After 14 months post incident with intense rehabilitation of six months his GCS score is improved with scoring of 13/15 (E4M6V3). The improvement seen may be partly attributed to the coordinated work of the team members who meet in the case conference every two weeks to review & revise the treatment protocol. Such that common and individual goals are shared and total therapy time is managed, to incorporate all goals by team members

Nagarjuna narayanasetti

The inclusion of hydroelectric power is crucial to Nigeria's overall energy mix, playing a significant role in electricity generation. However, the Shiroro hydro plant, one of the main facilities located on the Kaduna River, is currently facing operational obstacles due to deteriorating infrastructure and inadequate maintenance practices. To overcome these challenges and improve efficiency within Nigeria's hydroelectric power sector, a hybrid-optimization approach has been proposed. This study sought to enhance the efficiency of the Shiroro hydro plant by implementing this innovative method. To achieve our objectives and address pertinent research questions, a mixed research method combining primary and secondary data was employed. The analysis included hydropower modeling and hydro-turbine input-output modeling. Three optimizer models, namely the particle swarm optimizer (PSO), Ant colony optimizer (ACO), and Artificial bee colony optimizer (ABCO), were utilized to formulate objective functions and task representations. The study involved comparing the daily output and fitness response of the Shiroro hydro plant through swarm optimizer iterations. The findings revealed a clear correlation between the turbine's power output and the water flow rate and water column height, suggesting that altering these factors could significantly improve the plant's performance. The comparison of the PSO, ACO, and ABCO models demonstrated that PSO and ABCO generated optimal or near-optimal solutions, while ACO produced suboptimal results. Consequently, the study concluded that enhancing the Shiroro hydro plant's output was feasible by increasing the water flow rate and column height. Additionally, the utilization of PSO and ABCO models proved to be an effective means of accurately predicting the turbine's output. As a result, the study recommended the integration of hybrid optimization techniques to monitor and identify any deviations in the Shiroro hydro plant's daily power output. This approach would enable prompt maintenance to be carried out, preventing significant damage to the plant. Ultimately, this research contributes valuable insights into improving the efficiency and performance of Nigeria's Shiroro hydro plant.

Fxintegrity publishing

This work was focused on identification and evaluation of process parameters of modified nanoprecipitation method, for fabrication of lomustine nanoparticles, with the aim of reducing cancer cell viability at low concentration of lomustine. The parameters controlling particle size, mostly in nanosize, were solvent/nonsolvent composition and emulsification speed of homogenizer along with aqueous phase volume. This controlled particle size is below 250 nm. The stabilizer concentration controlled particle size is within 68 nm ± 0.89 to 137 ± 0.94 nm with PDI 0.06 ± 0.008 to 0.25 ± 0.001. But, the stabilizer addition mode showed more uniform size distribution with PDI 0.085 ± 0.004. Entrapment efficiency was maintained well above 47 ± 0.23%. The drug release pattern was monophasic with controlled release over 24 hrs. In the method used, drug content was affected by ratio of polymer to drug to organic solvent, as well as homogenization speed and time. Percentage viable cells of L132 human lung cancer cell line remained, were only 5% at 100 μg/ml lomustine equivalent PLA nanoparticles.

Archana mehrotra

This review shares historical glimpses of the art and science of urinary crystal growth in the gel. This successful journey of long and detailed research consists of theoretical and experimental knowledge. The survey consists of historical aspects of crystal growth, the development of urinary crystal growth in the gel as an in vitro urolithiasis model and the application of this model to evaluate prophylactic management against kidney stones.

Dr. salman ahmed

The Covid 19 pandemic affects many elements of a person's life negatively. This reduced concern and considered the major problems that people – especially adolescents and young adults – are experiencing. In this regard, the study examined young adults' mental health by looking at the relationship between welfare and several psychological characteristics, such as loneliness, suppression of mind, common anxiety, flexibility, and self-worth. A total of 134 young people (45 men and 89 women) aged 18 to 25 were recruited for the study by purposeful sampling. Information collection Questionnaires are used. The measurement measurements were the Rosenberg personality Scale, UCLA isolation Scale edition 3 and the Coping Capacity Questionnaire. The information was analysed by means of the coefficient of Pearson correlation and a z-test to determine results for various genres. In Pairson's product time correlation test, the above psychological features were linked to well-being. Self-esteem, well-being, resilience and well-being were found to be moderately good. All had a negative association between general anxiety and well being, solitude and wellbeing, and suppression of thought and wellbeing. The results of the Z-test showed no significant differences in psychological variable scores among men and women, meaning that the whole community felt a sense of harmony in difficult times regardless of gender. The gladness of the sample was 7.95 (ranging from 0 to 20), which was very low.

Dr. amarjeet singh

To the editor, Breast cancer remains one of the leading causes of cancer-related mortality worldwide, necessitating innovative and multifaceted therapeutic strategies. [1] We propose a promising combination approach that synergizes Artificial Intelligence (AI), oncolytic virotherapy, probiotic therapy, stem cell therapy, and immunotherapy to target breast cancer more effectively.

Karishma

Background: Hospital acquired infections (HAIs) are infections that patients acquire while receiving treatments for other conditions. Studies have shown that stethoscopes and sphygmomanometers can act as potential sources of these infections in patients accessing treatment in healthcare facilities. This study aimed to increase awareness among health workers in Nigeria of the potentials of stethoscopes and sphygmomanometers to transmit HAIs. Methods: Moist swab sticks were used to collect samples from 38 randomly selected stethoscopes and sphygmomanometers from some departments of four district hospitals. Collected samples were cultured using standard microbiological techniques. In addition, self-designed questionnaire was used to assess the knowledge and practice of doctors and nurses on the roles of stethoscopes and sphygmomanometers in HAIs. Results: About 83.8% of the health workers demonstrated some awareness of the roles of stethoscopes and sphygmomanometers in HAIs. 42.5% cleaned their stethoscopes, while 5% their sphygmomanometers. Staphylococcus aureus, (65.9% of stethoscopes), proteus mirabilis, Pseudomonas aeruginosa (67.6% of sphygmomanometers), Streptococcus and Coliform species were isolated. There was no significant difference between the contamination of stethoscopes and sphygmomanometers by the isolates, except for Pseudomonas aeruginosa (t=3.49, p=0.04). Conclusions: Awareness did not match practice in cleaning the stethoscopes and sphygmomanometers in the four facilities. Staphylococcus aureus and Pseudomonas aeruginosa were the two most common organisms isolated with a significant difference (t=3.49, p=0.04) between stethoscopes and sphygmomanometers in isolation of Pseudomonas aeruginosa. To curb HAIs, health workers need to improve on their practice of cleaning stethoscopes and sphygmomanometers.

Emmanuel umegbolu

Les études sur la langue française la présente souvent dans des situations où elle est en contact avec les langues africaines. Elle co-apparait avec les langues africaines dans les discours romanesques. Cette co-apparition n’est pas sans conséquences pour les deux langues en contact. Certains linguistes, surtout les sociolinguistes et les didacticiens, parlent d’insécurité linguistique. Ils la lient à toutes les situations linguistiques où deux langues entrent en contact. Ngamassu (2007, p.94) dit dans ce sens que « toute situation de contact des langues est source d’insécurité linguistique, car aucun locuteur/scripteur ne peut maîtriser toutes les variétés ou niveaux d’une langue ». Cette affirmation restreint l’insécurité au locuteur ou au scripteur. Les linguistes ignorent souvent l’impact négatif du contact des langues et s’intéressent à ses conséquences positives. Cet article a porté sur les manifestations de l’insécurité linguistique dans la prose romanesque de Kourouma et Badaman. Il a permis de voir que l’usage des langues maternelles dans le français constituait une menace de disparition et d’abâtardissement de la langue française.

Assanvo

Lateral epicondylitis, commonly known as Tennis Elbow, affects approximately 1-3% of the population. Despite the absence of histological evidence of inflammation in the affected tissue, the term “epicondylitis” implies inflammation. The Extensor Carpi Radialis Brevis (ECRB) muscle is primarily affected, and the condition is attributed to excessive use of this muscle. Non surgical treatment options, such as rest, physiotherapy, cortisone injection, platelet-based therapies, and restricted movements, are recommended. Surgical intervention is suggested for cases involving physical impairment or chronic pain. This review aims to provide healthcare professionals with an understanding of the condition, including its causes, symptoms, diagnosis, and treatment planning options.

Saran malisorn

Stem cells hold great promise for tissue regeneration and have the potential to treat many incurable degenerative diseases. Cancer stem cells (CSCs), or cancer initiating cells, have the ability to self-renew and differentiate into heterogeneous lineages of cancer cells. Current stem cell therapies face limitations, such as limited stem cell sources, time consumption, tumor formation, and immune rejection upon allogeneic transplantation. Allogeneic stem cell treatments simplify stem cell manufacturing and reduce transplant time, but their therapeutic potential is limited by human leukocyte antigen (HLA)-matched donors. CSCs retain characteristics essential for tissue regeneration. However, several limitations hinder cancer stem cell reprogramming with pluripotent factors. The development of 3D culture models for tissue imitating extracellular matrix in cancer cell lines aims to enhance CSC enrichment. This mini-review focuses on a new strategy for treating incurable degenerative diseases involving in vitro and in vivo 3D cancer models and the induced differentiation of CSCs into mature normal cell types. This allows tissue survival without immune rejection and offers a safe alternative to cancer stem cell reprogramming with pluripotent factors. In conclusion, preservation and banking of allogeneic CSCs offer an alternative, readily available, and safe strategy that can be used to facilitate stem cell-based cell therapy.

Josita alloysius

Crinum jagus, family- Amaryllidaceae, commonly called river lily is an important medicinal plant used in the treatment of cough. It is an anti-venom agent used among the rural people in south-western Nigeria. The research is aimed to investigate the phytochemical constituents and analgesic activity of Cinium jagus bulb in BALB/c mice. The bulb was extracted with methanol in a soxhlet extractor apparatus. Phytochemical screening was performed according to standard methods. Alkaloid fraction was obtained using separation by extraction and characterized by infra-red (I.R) analysis. Acute toxicity test was done before analgesic activity was determined in BALB/c albino mice using the hot plate model. The result indicated the presence of some bioactive constituents like alkaloids, terpenoids and saponin. I.R bands were observed at 1064.74 cm 1 (C-O) stretch of alcohol; 1415.80 cm-1 (C-H) bend of alkyl groups and 1639.55 cm-1 (N-H) stretch of amine among others. The extract significantly increased the mean latency time of mice on the hot plate when compared with control with 100 mg/kg at 120 minutes. This study indicates that the Crinum Jagus bulb possesses analgesic potential.

Mediterranean journal of pharmacy and pharmaceutical sciences

Hepatitis B virus infection is a major health problem worldwide. More than 400 million people are suffering from this infectious disease. Alhagi Maurorum (camel thorn, CTE) is used in Libyan folk medicine for hepatitis. The aim of this study is to investigate the effect of the camel thorn on the hepatitis B virus. After a pharmacological and toxicological screening of camel thorns on experimental animals in our laboratories, in an open-label study, 15 patients of either gender were chosen at random with their consent (consent form signed). The patients had no liver cirrhosis and were not alcoholics. Following clinical testing, the patients were given a low, safe dose of camel thorn powder (2.6 g soaked in boiling water for 10 minutes) three times per day for six months. The viral load was measured before treatment and three and six months after the beginning of the experiment by polymerase chain reaction. The complete blood picture, the level of transaminases, bilirubin, creatinine, blood glucose, lipid profile, thyroid function, and prothrombin were assessed before and after three months after the beginning of the experiment. Our data showed no significant changes in the complete blood picture, creatinine, blood urea, glucose level, bilirubin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lipid profile, prothrombin, and thyroid function. The levels of viral load before, three months after, and six months after the beginning of our study were 1689 ± 289, 558 ± 160, and 271 ± 026 IU per mL, respectively. From this study, we may conclude that the camel thorn is safe and showed activity against viral hepatitis B, however, further investigations are needed by increasing the number of patients and using higher doses of plant extract to explore its mechanism of action. Finally, the mechanism of camel thorn may be related either to its antiviral effect or to the stimulation of either endogenous interferon or the immune system.

Mediterranean journal of pharmacy and pharmaceutical sciences

Currently, there are three popular theories of corporate governance widely applied in the field of jurisprudence worldwide. They are Agency Theory, Stewardship Theory, and Stakeholder Theory. Based on these theories, the article focuses on clarifying legal issues about corporate governance, thereby suggesting solutions to the improvement of corporate governance legislation in Vietnam at present time

Iaeme

Immunoglobulin G4-related disease (IgG4-RD) is a rare and new but increasingly recognized immune-mediated fibroinflammatory condition known to affect multiple organs. The diagnostic approach is challenging, as there is no single investigation to confirm the diagnosis, which requires the integration of clinical, biochemical, and radiographic manifestations with classic histopathologic features to establish the diagnosis. The histology of IgG4-RD is determined by a dense lymphoplasmacytic infiltrate, storiform fibrosis, and obliterative phlebitis in the presence of an increased level of IgG4 in most patients. The first line of treatment is systemic glucocorticoids, but adverse effects of the drug, suboptimal response, and disease recurrences on reduction or termination of therapy highlight the need for an alternative therapy such as rituximab, which appears to be a promising alternate agent in the treatment of IgG4-RD; however, its efficacy needs to be evaluated in large clinically controlled trials.

Karishma

The current COVID-19 is now endemic on everycontinent and becomes the most challenging outbreaks over centuries, thus millions of people have been infected with the novel coronavirus (SARS-CoV-2), and have contributed to the deaths of more than two millionpeople. Researchers are working continuously to develop safe and effective vaccines that people have started receiving since December 2020. Vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are the most important countermeasure to the COVID-19 pandemic taking into considerationthat vaccines induce a robust immune response

Mediterranean journal of pharmacy and pharmaceutical sciences

Cystic fibrosis is a challenging disease which creates many complications. The impact caused from cystic fibrosis on an adolescent is a challenging phase for their lives. Negative impacts like the society’s pressure, anxiety and depression are few common reasons that are being unspoken and ignored due to complexity of the disease. This study is aimed to identify the necessary gaps and educate the necessary policy makers and CF center health care team to have a better understanding about the context of the aftermath of cystic fibrosis and enhance better patient care. More over this systematic review also points out the main trends in this field of study. Qualitative study and quantitative are prominently used research methods to gain an understanding the about the gaps in the research. However, there is still a scarcity of quantitative and mixed research methods. Furthermore, limitations such as language, cultural influences were identified whilst going through the analysis. Overall through the information given in the following in this study more information regarding that warrants answers can be identified which will lead to proper care towards the teenagers who suffers from cystic fibrosis.

Chanitha pemasena

Background:The systematic management of microbial bioburden in Class C healthcare cleanrooms is a critical factor in patient safety. Standard environmental monitoring often overlooks the complex spatial and statistical relationships of contamination. This study applies a rigorous statistical framework to a comprehensive environmental monitoring dataset to accurately map contamination risk.Methods:A cross-sectional analysis was performed on 318 microbial surface samples from 28 distinct operational locations in a Class C facility. Colony Forming Unit (CFU) data were analyzed using non-parametric statisticsdue to non-normal distribution, confirmed by Shapiro-Wilk tests on all locations with sufficient sample size (n=12). The Kruskal-Wallis test with Dunn's post-hoc analysis was used for group comparisons. Spearman's correlation was used to assess inter-location relationships.Results:Significant spatial heterogeneity in microbial contamination was confirmed (p<0.0001). Dunn's test identified CP C 11 W as the location with the highest contamination burden (mean CFU=12.17). The most statistically robust contrasts were observed when comparing high-burden sites against the cleanest location, CP C 32 WNme(mean CFU=0.67), which serves as a control benchmark. Multiple high-burden locations, including CP C 11 W and CP C 30 NCu, were found to be significantly more contaminated than this benchmark. No Spearman correlations survived the strict Bonferroni correction; however, the relationship between CP C 11 W and CP C 45 Wif (r=0.882, p<0.05) approached the significance threshold, suggesting a potential pathway requiring further investigation.Conclusions:Microbial contamination within the facility is spatially patterned, not random. The analysis provides a definitive hierarchy of risk, highlighting CP C 11 W as the primary target for enhanced sanitation. While correlational pathways could not be statistically confirmed, near-significant results provide a clear direction for future, more targeted sampling to validate operational links between zones.

Mostafa eissa