A large number of people suffer from gallstones worldwide, and this problem is now increasing significantly due to malnutrition, changes in living lifestyle, lack of exercise and conditions, i.e. industrialization. Medicinal plants have been used for centuries due to their cultural acceptability, efficacy, safety and fewer side effects than modern synthetic medicines. This review aims to gather information on the plants utilized in various parts of society against gallstones. The information provided is beneficial for ordinary people and the scientific community for further phytochemical, toxicological and pharmacological studies, which may lead to the discovery of new, more effective and safer medicines for gallstones.

Dr. salman ahmed

In this article, a systematic flow of contents was provided with regard to the synthesis of Atovaquone 1a on critical examination of the prior-arts. Several patents and study articles were published, disclosing different synthetic methods for the preparation of Atovaquone 1a at various scales. Based on the starting materials used, there are a few one-step, two-step and multi-step synthetic routes were reported with varied yields. In this work, we have put in our sincere effort to collect all the synthetic routes of Atovaquone 1a in detail with distinct and elaborate reaction schemes for a better and collective process clarity. From this review, global researchers will get a platform to re-design or re-work on the synthetic approach of Atovaquone 1a with better atom economy and purity. In addition, the drug commercialization angle could also be looked in during the design stage itself alongside green chemistry concepts. We have done the chronic analysis of study articles to highlight the commercial feasibility of the disclosed synthetic methods. A special emphasis was given to the synthetic routes with process development initiatives towards, recovery/reuse of costly starting materials/reagents/solvents and their feasibility for large scale manufacturing of drug Atovaquone 1a.

Mediterranean journal of pharmacy and pharmaceutical sciences

The study examined the impact of school enrolment growth on the carrying capacity of universities in Imo State, Nigeria. Three research questions and hypotheses guided the study. The study adopted the descriptive survey design with a population of 2,929 academic staff in the two public universities in Imo State. The sample size was 352 representing 12% of the population drawn using stratified random sampling technique. An instrument titled ‘School Enrolment Growth and Carrying Capacity of Universities Questionnaire (SEGCCUQ)’, structured on the 4 point scale, validated by experts and with reliability index of 0.84 was used for data generation. Mean and standard deviation were used to answer the research questions while z-test was used to test the hypotheses at 0.05 alpha level. Among others, the study revealed that factors such as natural increase of population, influx of migrants, enforcement of compulsory education, raising of school-leaving age, increased enrolment of girls and so on influence school enrolment growth that bear on the carrying capacity of universities. It was recommended among others that the factors should help the governments and institutions to forecast enrollment more effectively likewise permit them to make adjustments to meet current or future enrolment.

Fxintegrity publishing

At present, numerous approaches have been verified and suggested in relation to the innovation policy formulation of the enterprise. However, less attention is paid to regions in the developing world. An attempt is made in this thesis towards that direction. I argue that from the system of innovation theory perspective, innovation policy practice for regions in the developed world is a problem solving based process, due to the path dependency of innovation policy and the development level of advanced economies. For this purpose, the article proves the possibility of every company’s making much more profit by realizing and improving effective innovative management in the developing economy. And, it will be calculated and assessed the correlation link between the costs of innovation and total revenues of the world’s most innovative companies. In the end, it will be done some conclusions and discussions of nowadays innovators practice.

Ikboljon odashev mashrabjonovich

Research on treatment for diabetes and co-occurring eating disorders is sparse. We examined outcomes from multidisciplinary residential treatment for women with type 1 diabetes and eating disorders and the impact of treatment duration on outcomes. Participants were 29 women with type 1 diabetes and eating disorders receiving residential treatment. Repeated measures analyses of variance examined changes in blood glucose and psychological symptoms over treatment. Analyses were repeated to include treatment by duration interactions. Treatment produced significant reductions in blood glucose, eating disorder symptoms, and psychological concerns. Longer treatment duration was associated with greater improvements in psychological symptoms. Disordered eating is alarmingly common among individuals with type 1 diabetes mellitus, with rates of co-occurring diabetes and eating disorders estimated as high as 40% (Young etal., 2012; Young-Hyman & Davis, 2012). The most commonly noted link between type 1 diabetes and eating disorders is in the form of purging through insulin omission for weight loss purposes (Darbar & Mokha, 2008), which has been noted for individuals with diabetes co- occurring with anorexia nervosa (AN), bulimia nervosa (BN), and eating disorder not otherwise specified (EDNOS; Nielsen, 2002; Peveler & Fairburn, 1989). However, even among individuals with diabetes who do not omit insulin, eating disorder symptoms are elevated (Jones, Lawson, Daneman, Olmsted, & Rodin, 2000).

John dolores

The present study focused on analysing the impact of ‘Make in India’ campaign on FDI inflows in country. The research period is divided in two parts one is pre ‘MII’ & another is post ‘MII’ period. The analysis of ‘Make in India’ campaign is done to identify the scope of the campaign & methodology of working of various allied departments monitoring campaign. The present research work also attempted to take overview of various policy reforms initiated by Government of India to promote the FDI as well domestic investment in 25 sectors shortlisted under MII. The FDI inflows statistics reveals that, the post MII period is showing the highest growth in FDI equity inflows as compare to same period i.e. 2009- 2014. The MII initiative is one of the reason for the jump in FDI inflows. The overview of policy reforms shows that GOI through DIPP attempted to open almost all sectors for 100% FDI through automatic route. Government has provided multiple incentives for Foreign Investors to establish their manufacturing facilities in country but very negligible response has been seen in the nature of FDI equity inflows in the same period. Further results of study reveals that multiple ‘MOU’s have been signed by States & Central Governments, but they yet not converted in actual investments. The major reasons behind the same is lack of SWOT analysis through Governments before inviting the foreign investors. As well lack of basic infrastructure, land, lack of skilled manpower, cheap & un interrupted power supply to MIDC’s & SEZ’s is yet not successfully provided, lower rankings in Ease Of Doing Business (EODB), Global Manufacturing Competitiveness Index (GMCI) is also cause of concern & tumbling block in the success of MII mission..

Anshuman vijay magar

In the present study, the bacterium Achromobacter xylosoxidans was isolated from tannery effluent sludge sample in Dindugal, Tamil Nadu, India and screened for its bio-control efficacy against selected plant pathogens viz., Alternaria solani, Curvularia lunata and Fusarium oxysporum under in vitro. It was observed that maximum percent inhibition of mycelial growth of C. lunata (95%), followed by A. solani (85%) and F. oxysporum (80%). An attempt was also made for testing its plant growth promoting traits such as production of Indole acetic acid (IAA), phosphate solubilization efficacy, Hydrogen cyanide (HCN), ammonia and catalase production. Significant amount of plant growth promoting traits were noticed. Further studies on mechanism of bio-control against plant pathogens and plant growth promoting activities of Achromobacter xylosoxidans need to be conformed under in-vivo condition.

Dr. saranya devi k

Kidney transplant kidney transplant ( KTx) recipients have increased susceptibility to a spectrum of infections including; bacterial, viral, and fungal pathogens. Many factors contribute to their infection potential risk, in terms of their immunosuppressive state, that result in suppression of their B‑and T‑lymphocyte repertoire, also to consider certain donor and recipient‑related factors, that make them at risk of specific type of infectious complications. In addition kidney transplant patients tolerate poorly infections, which may adversely affect their graft function, by inducing glomerular injury, hence early diagnosis, directed therapy, and careful dosing of antimicrobial agents is of paramount importance in reducing patient’s morbidity and mortality. We report a kidney transplant patient, who received her live related kidney graft 7 years earlier (in 2013), she has been with stable graft function in most of her follow up period, until she presented with pyrexia, dyspnea and fatigue associated with deterioration of her graft function.

Hani

Introduction: Mental health disparities are deeply entrenched within the fabric of societal inequalities, shaped by structural factors that perpetuate intergenerational cycles of disadvantage. Addressing these disparities is crucial for promoting social justice and improving public health outcomes. Aim: This paper aims to synthesize high-quality evidence to elucidate the causal relationships between social determinants and mental health outcomes. It prioritizes pervasive social determinants that influence major mental disorders across the life course and outlines preventive strategies to mitigate these effects. Methodology: A comprehensive literature review was conducted, focusing on publications from the Global North from 2014 to 2024, to explore the influence of social determinants on mental health. Keywords such as "social determinants," "mental health outcomes," "preventive strategies," and "vulnerable populations" guided the search across databases like PubMed and Google Scholar. Results: The review highlights significant associations between mental health and social determinants such as socioeconomic status, racial and ethnic marginalization, and exposure to adverse environments. It underscores the heightened vulnerability of marginalized groups, including refugees, LGBTQ+ individuals, and those living in poverty. The paper introduces a preventive framework to guide primary prevention efforts and reviews both primary and secondary strategies to improve mental health equity. Conclusion: Strategic interventions aimed at the root social causes of mental health disparities can substantially enhance public mental health. This paper provides seven strategic recommendations focused on social justice, offering a roadmap for researchers, policymakers, and public health professionals to address these pressing issues.

Prof.k.c yadav

Background and Objectives: The Bayelsa Health Insurance Scheme (BHIS) is a state-designed social security plan in which enrollees benefit from a shared pool of cash based on premiums paid by participants. The study aimed to assess the self-reported effectiveness, service utilization, level of satisfaction, and barriers among beneficiaries, and proffer solutions to improve the scheme. Methods: The study was a descriptive cross-sectional survey using a structured questionnaire. This questionnaire assesses the BHIS impact in Kolokuma/Opokuma LGA through six sections capturing demographics, service utilization, satisfaction, financial implications, access barriers, and improvement solutions using standardized scales and matrices, preceded by informed consent. Data was analyzed using SPSS and Microsoft Excel. Results: The major barriers to service utilization were constant unavailability of claimed services at accredited facilities (90.1%) excessive waiting time (76.4%), late/non-referral to specialized centers (67.5), rigid BHIS protocols (63.1%), insufficient insurance coverage (55.2%), complex billing systems (50.7%), and shortage of BHIS staff (50.0%). Conclusions: Possible solutions include the training and retraining of staff and service providers, providing subsidies for couples who are both government employees, initiating adequate supervision, monitoring, and feedback mechanisms, rapid referral protocols, and integrating and encouraging the establishment of health equity funds.

Karishma

This paper found that 35% of Adivasis have health problems, and 73% said that they are getting treatment with RMP. 87% have toilet facility and more than 12% still defecate openly. 18.3% said that they faced different problems at open defecation, and 50% of women not using sanitary napkins. Nearly 90% of respondents wash their hands after toilets and coming from outside of the home. Ten per cent of respondents said that they do not have an awareness of sanitation. Therefore, the study confirmed that the sanitation facilities considerably made the women's dignity and quality of life better in the study area. Moreover, four case studies also focused on open defecation problems in the study area.

B suresh lal

This abstract provides an overview of the critical role of academic leadership and governance in higher education institutions. As the landscape of higher education undergoes profound transformations, academic leaders and governance structures play a pivotal role in shaping the direction, quality, and effectiveness of educational institutions. This abstract highlights key themes, challenges, and considerations related to academic leadership and governance, emphasizing the need for adaptability, transparency, and inclusivity in the decision-making processes. The abstract begins by acknowledging the evolving nature of higher education and the increasing complexity of issues facing institutions, including technological advancements, changing student demographics, and shifting funding models. It underscores the central importance of academic leadership and governance in addressing these challenges and promoting institutional excellence.

Dr gedam kamalakar

Though the anatomy and physiology of the adult caprine (Capra hircus L.) stomach have been investigated extensively, the early development of the abomasum has not yet been fully elucidated. The glandular part of abomasum plays an important role in digestion of ingested food by action of gastric juices. Very few studies have been conducted so far regarding histogenesis of goat foetal abomasum in India. In the present study, we have investigated the embryonic and early foetal development of the goat, Capra hircus L. fundic abomasum. We collected 36 developing abomasum of healthy and normal embryos/foeti of goat and assigned them into three group viz. Gr. I (0-50 days of gestation), Gr. II (51-100 days of gestation) and Gr. III (101-150 days of gestation). Small pieces of tissues were processed by routine paraffin. The wall of glandular stomach, the fundic part, was composed of epithelium, pleuripotent blastemic tissue and serosa up to 44 days of gestation. Tunica muscularis became separable at 46 days of gestation. The epithelium was stratified type up to 50 days and gradually changed to pseudo-stratified columnar to simple columnar type from 76 days of gestation. Primary and secondary abomasal folds were observed at 51 and 76 days of gestation, respectively. Gastric pit, the fore runner of gastric gland was reported first at 70 days. The gland became branched tubular type at 145 days. The cells found in the mucosa of the abomasum were surface epithelial cells, chief cells, parietal cells, mucous neck cells and undifferentiated cells. Chief and parietal cell were observed at 76 days and mucous neck cells at 82 days of gestation. Reticular, collagen and elastic fibers came into sight at 38, 76 and 100 days of gestation, respectively. The present study is expected to supplement known data and knowledge regarding histogenesis of goat fetal abomasum and help in diagnosis and treatment of related congenital anomalies.

Varsha gupta

Mano Matram Jagat; Mano Kalpitam Jagat - (“the world is as the mind sees and feels it; the world is as the mind thinks of it” (as qtd. by T.N.Sethumadhavan, 2010). So, our life is in the way we feel and perceive it. Humans are a mixture of emotions and reasons. Reasoning enables them to analyze and judge things with mathematical precision, while emotions help them to understand and empathize others that make them human. Traditionally, people with a high degree of logic and reasoning were believed to be intelligent and. The purpose of the IQ tests was designed to ascertain a person’s intelligence based on the reasoning and the logical aptitude of the person. IQ tests were found to be effective when a person is ‘not’ scared or angry or intrigue about specific things that aroused emotions. Emotions were considered disruptive in nature, which influences the process of thinking of a person (Woodworth, 1940). Mowrer (1960) opined that “emotions are of quite extraordinary importance in the total economy of living organisms and do not deserve being put into opposition with intelligence‟. The emotions are, it seems, themselves a higher order of intelligence.”

Aurora lyrics

An experiment was carried out during kharif 2017 at Zonal Research Station, Chianki using sixteen promising genotypes of okra with three replications in randomized block design. Observations on ten important quantitative characters were recorded. Analyzed data revealed that all characters showed significant effect. The genotype Ajeet-121 gave significantly highest yield with the yield of 135.12 q/ha followed by NS-862 and Super green with the yield of 134.75 q/ha and 134.02 q/ha, respectively. Average fruit weight (15.33 g) and yield of fruits per plant (245.67 g/plant) were recorded significantly highest in the genotype Ajeet-121. On the basis of these observations, it may be concluded that the genotype Ajeet-121 was found most suitable okra genotype for kharif cultivation in the western plateau region (sub zone-V) of Jharkhand.

International journal of agricultural and applied sciences (ijaas)

The formation of social sciences in general, and sociology in particular, often includes foundational courses such as Introduction to Sociology as part of its curriculum. Many of these courses traditionally place the teacher at the center of teaching, with learners acting as passive recipients of knowledge. This approach limits learners' initiative in seeking knowledge and expressing their own perspectives on social issues, thus excluding them from the knowledge production process. This contradicts modern educational principles that emphasize learner participation in the educational process. Therefore, adopting a constructivist perspective of teaching necessitates the use of new teaching methods, with the Photovoice method being one of the essential tools due to its emphasis on participatory learning. Participatory learning involves students actively engaging with and redefining the knowledge presented in the classroom, rather than passively receiving it. This paper describes our experience using the Photovoice method in the Introduction to Sociology course at Ho Chi Minh City Open University, Vietnam, during the first semester of the 2023-2024 school year. Additionally, the paper presents survey results reflecting students' opinions on the Photovoice method after completing the course. The survey data indicates that Photovoice is an effective pedagogical tool.

Le minh tien

Financial sector needs special attention pertaining to incorporation of the ESG criteria. Economic and financial issues coupled with climate change would have negative impact on the stability of financial institutions. This research paper attempts to synthesize and summarise scholarly articles published in Scopus database on ESG domain with reference to banking sector using bibliometric analysis. The objective of this review paper is to understand from past literature the trajectory of studies in the domain of ESG. There is a substantial growth in frequency of publication in the year 2022 along with annual growth of around 30 percent during 2015-2023. Bibliometric with MS-Excel, R-Studio and VOS-viewer were used to identify and analyze research trends related to the number of studies, research fields, authors, nations, institutions, and keywords. The important keywords identified in the bibliometric analysis were sustainability, corporate social responsibility, sustainable finance, banks performance.

Dr. mohammed nizamuddin

The orientation he/she chooses has a bearing on his/her long-term success. This orientation is known as your "locus of control." Its study dates back to the 1960s, with Julian Rotter's investigation into how people's behaviours and attitudes affected the outcomes of their lives. Locus of control has been defined as the degree to which an individual perceives having control over the environment (Rotter, 1966). According to Rotter (1975), there are two types of control, internal and external, which anchor a continuum that approximates a normal distribution. People are said to have an internal locus of control when they believe reinforcements are contingent upon their own behaviour or stable personal characteristics. External locus of control results when people believe that reinforcements are due to luck, fate, or powerful others outside of their control. Current study focuses on investigating the influence of demographic variables (age, gender, education level), marital status and socio economic status (occupation, income) on the level of internal/ external locus of control with the help of data collected from residents (aged between 20 and 50) of a select suburbs in Mumbai city. On analysing the data so collected, it is found that age has a major influence on an individual’s level of internal locus of control.

Nandini

Crinum jagus, family- Amaryllidaceae, commonly called river lily is an important medicinal plant used in the treatment of cough. It is an anti-venom agent used among the rural people in south-western Nigeria. The research is aimed to investigate the phytochemical constituents and analgesic activity of Cinium jagus bulb in BALB/c mice. The bulb was extracted with methanol in a soxhlet extractor apparatus. Phytochemical screening was performed according to standard methods. Alkaloid fraction was obtained using separation by extraction and characterized by infra-red (I.R) analysis. Acute toxicity test was done before analgesic activity was determined in BALB/c albino mice using the hot plate model. The result indicated the presence of some bioactive constituents like alkaloids, terpenoids and saponin. I.R bands were observed at 1064.74 cm 1 (C-O) stretch of alcohol; 1415.80 cm-1 (C-H) bend of alkyl groups and 1639.55 cm-1 (N-H) stretch of amine among others. The extract significantly increased the mean latency time of mice on the hot plate when compared with control with 100 mg/kg at 120 minutes. This study indicates that the Crinum Jagus bulb possesses analgesic potential.

Mediterranean journal of pharmacy and pharmaceutical sciences

This study aims to assess tourists‟ perceptions towards quality tourism services provided at Petra historical site, and to measure tourist satisfaction by examining the impact of quality tourism product on overall tourist satisfaction. In this study, four hypotheses were developed are proposed a study model. The empirical data were collected from tourists via a survey that yielded 180 usable questionnaires, these data were analysed using a series of multiple regressions to determine the relationship between service quality and tourist satisfaction. The findings confirmed that service quality directly impacted tourist satisfaction throughout destination facilities, destination accessibility and destination attraction. As a result, this study argued that there is a significant impact of the service quality on tourist satisfaction, and therefore service quality plays an important role in tourism by increasing the level of tourist satisfaction. The results in this study supported the evidence that there are positive impacts of components of tourism product on tourist satisfaction. This study provided some theoretical and managerial implications based on the findings to academicians and tourism sector, the researcher presented recommendations for further studies and he discussed the main limitations in this study

Mukhles m. al-ababneh