Plants produce a diverse range of bioactive compounds making them a rich source of different types of medicines. Ornamental plants are cultivated for adornment and to enhance the appearance of houses and also for commercial purposes. However, only very few of these ornamental plant species have found to be used in medicine and only little literature exit on their chemical and biological actions. In the present study, the evaluation of antimicrobial activities and identification of bioactive compounds using TLC and GC-MS of the A. columnaris bark extract were performed. In GC-MS bioactive compounds with medicinal value were identified, such as Benzoic acid, 1H-N-Hydroxynaphth (2,3) imidazole-6,7-dicarboximide, 2-Propenoic acid, 3-(4-methoxyphenyl), 1H-N-Hydroxynaphth (2,3-d) imidazole-6,7-dicarboximi. To prove the nontoxic nature of the plant, its crude bark extract was subjected to toxicity study using human embryonic kidney cell line. It reveal that the plant is minimal toxic to the human kidney cell line so usage of appropriate level will found to be safe and also carrying out some structural modification will help in the extraction of new drugs for pharmaceutical purpose.

Dr. saranya devi k

Urolithiasis is a common worldwide problem with high recurrence. This review covers Euphorbiaceae twenty (20), Cucurbitaceae eighteen (18), Acanthaceae and Amaranthaceae fifteen (15), Cupressaceae twelve (12), Caryophyllaceae eleven (11), Anacardiaceae ten (10), Amaryllidaceae, Apocynaceae and Asparagaceae nine (09), Ericaceae and Equisetaceae eight (08), Arecaceae and Caesalpiniaceae seven (07), Chenopodiaceae six (06), Aspleniaceae, Capparidaceae and Crassulaceae five (05) plants used globally in different countries. Hopefully, this review will not only be useful for the general public but also attract the scientific world for antiurolithiatic drug discovery.

Dr. salman ahmed

Anemia, iron deficiency and iron deficiency anemia are common blood disorders. The role of vitamin D was agreed to be regulating in calcium and phosphate absorption and bone metabolism and its deficiency is observed as a crucial nutritional problem. Vitamin D is created under the skin by ultraviolet light. It is usually get vitamins from the food; however, in the case of vitamin D, there simply are not enough rich food sources for people to get adequate amounts in their diet. Its effects on the prevention of diseases such as cardiovascular disease and anemia has received much attention recently. To get sufficient vitamin D, need to be exposed to sunshine or use supplements. Vitamin D3 was found in the largest population as a deficiency. With regard to hemoglobin was the subject whom has less normal range of hemoglobin (19.05%) than international normal range, and in ferritin the low population number was the subject whom has less normal range of ferritin than WHO normal range. The population who has low ferritin also has low vitamin D3 and variable hemoglobin. According international guidelines, optimizing nutrition with daily or intermittent (1 to 3 times per week) iron supplementation, should be considered a first-line intervention in high-risk or high-prevalence groups. Although it is probably less effective than daily iron supplementation, intermittent iron appears to be a useful and cost effective way of controlling anemia and iron deficiency anemia. This may indicate that a positive relation between the low concentration parameter of vitamin D3 and ferritin level but no significant correlation with hemoglobin.

Mediterranean journal of pharmacy and pharmaceutical sciences

This is a study on the growth of public relations in Malaysia based on the advertisements placed in the newspapers during the colonial period. Tracing the historical development serves to make a better understanding about the nature of public relations practice. This paper therefore aims at exploring the development of the public relations profession by studying the advertisements placed in the nationwide newspapers, the Straits Times and the Singapore Free Press & Mercantile Advertiser from 1939 which included the early advertisement that contained the phrase “public relations” to 1956 a year before the independence of the Federation of Malaysia. An analysis of the advertisements was made to fully understand the historical development of public relations in Malaya or then Malaysia. The very first advertisement that was identified was on 31 January 1948, which was placed by the Department of Public Relations of the federal government. The British colonial government had placed another four advertisements in 1949 and 1950. A British mining Co. was the first corporation to hire an information & public relations officer in 1956. The results showed some differences and similarities through the analyses of advertisements in the job specification, which included qualification, duties, and salaries. The results revealed that those who had higher education and experience obtained a higher salary. The results also showed that some advertisers companies/ organizations had substituted academic qualifications for working experience) when advertising for their public relations personnel.

Mohammed fadel arandas

The study examined psychological predictors and mediators of teacher subjective well-being. Participants included 174 teachers from urban middle and highschools. The first objective was to explore the psychological correlates of the teacher SWB: self-esteem, general self-efficacy (core self-evaluation), teacher self-efficacy, optimism (cognitive trait related to the psychological well-being), and perceived social support (psychosocial trait related to the psychological wellbeing. The second objective was to investigate the mediating role of self-efficacy in the association between optimism and subjective well-being. The third objective was to explore the mediating role of teacher self-efficacy in the relation between perceived social support and teacher subjective well-being. Correlation, linear regression and mediation model analyses through the Sobel test were computed. Results confirmed the research assumptions. The findings of this study enhance the understanding of personal factors associated with teacher subjective wellbeing. The constructs linked to subjective well-being (predictors and mediators) could be target of school psychologists’ interventions, in order to have more engaged and performing teachers in schools. The findings were discussed in the context of designing the interventions for enhancement of the subjective wellbeing among teachers.

Elena stănculescu

Compliance with pharmacological therapy is the primary key to treating diabetes, but it has not received full attention from clinicians. Several systematic reviews of compliance factors have been conducted in several regions of the country. However, it does not feature studies from Indonesia. This study aims to systematically review the factors that can influence adherence to diabetes mellitus (DM) medication in Indonesia. A systematic literature review was conducted by searching the National (Garuda and Sinta) and International (PubMed and Science Direct) journal databases. Research that met the inclusion criteria was published from January 2011 to December 2020. The quality of the study was assessed using the SQAT guidelines. The research reporting method uses the PRISMA guidelines. Compliance factors are classified based on the domain of compliance factors, according to the World Health Organization (WHO). A total of 370 scientific research articles from the Garuda database (n=36); Science Direct (n = 108); PubMed (n = 18); Sinta (n= 208). Three hundred forty-one research articles were excluded, 29 full-text screening articles, and 16 research articles met the inclusion criteria for analysis. Factors that influence adherence to taking diabetes medication are social and economic (income, education level, and occupation), factors of personnel and health systems (health workers), factors of patient therapy (amount of diabetes medication, frequency of taking medication, and drug products), factors patient's disease (blood sugar levels, disease duration), patient factors (gender, emotional factors, social support, level of knowledge, and treatment satisfaction), and disease management factors (pharmacy counseling and education). Factors that influence adherence to taking DM medication in Indonesia are very diverse and are multi-factor. These factors can serve as relevant intervention targets. Clinicians must consider adjusting the frequency of taking medication and providing social support to DM patients.

Much ilham novalisa aji wibowo

ABSTRACT- Objective- The principal objective of the present investigation was the preparation of several analogs to further evaluate the binding site hypothesis. Aryl semicarbazides have also been reported to display excellent anticonvulsant activity in mice and rats. Method- In this project, the synthesis of semicarbazone derivatives was carried out. All molecules were synthesized using the common starting material –aniline. In all compounds, an intermediate was first formed by substituted phenyl urea using substituted aniline and potassium cyanate, and then it was hydrolyzed to get substituted phenyl semicarbazide, which was directly coupled with ketones. All the synthesized compounds were biologically screened for their anticonvulsant activity by the MES method. Result- Standard error mean was calculated concerning standard and control drug, Phenytoin sodium (25mg/kg.) and DMSO. The synthesized semicarbazone was characterized by using IR Spectroscopy. One another representative molecule compound was characterized using 1H NMR Spectroscopy. Conclusion- It can be concluded that designed semicarbazones were synthesized and characterized successfully. After synthesis of designed semicarbazones compounds were evaluated for anticonvulsant activity. Finally, two compounds have shown better activity in comparison to the other molecules.

Ajay garg

Recently studies showed that globally, more than 1.8 billion adults are overweight and in that around 650 million are obese. India is one among the most widely recognised countries which are identified with way of life today as being overweight. Obesity or overweight leads to heart diseases, Diabetes Mellitus, Hypertension etc. Objectives: Adulthood is a period where we have to pay at most attention tohealthy nutritional diet. Preventive measures through assuring the nutritional status of adults such as anthropometric, dietary survey, food consumption pattern, nutritional awareness, physical activity and alertness about diseases will assist the community from being overweight and thus the occurrences of metabolic disorders. Methods: zone chosen for the conduct of the study was Tirupati and based on the number of subjects required, their age profile; willingness to participate in the study; their health condition etc,. a private company which was willing was selected. The subjects chosen were in the age group of over 30-40 years. The selection was carried out using the purposive sampling technique. Results: The data indicates that some adults are in the border line of non-communicable diseases such as overweight or obesity, cardio vascular diseases, Type 2 diabetes and hypertension. Conclusion: This could be rectified through regular practice of consuming a nutritious and appropriate diet in conjunction with physical exercise routine.

Kimeera ambati

Digital data is growing enormously as the year passes and therefore there is a need of mechanism to protect the digital contents. Image watermarking is one of the important tools for the human to provide copyright protection and authorship. For achieving the ideal balance between imperceptibility and robustness, a robust blind color image watermarking employing deep artificial neural networks (DANN), LWT and the YIQ color model has been presented. In the suggested watermarking method, an original 512-bit watermark is applied for testing and a randomly generated watermark of the same length is used for training. PCA is used to extract 10 statistical features with significant values out of 18 statistical features, and binary classification is used to extract watermarks here. For the four images Lena, Peppers, Mandril, and Jet, it displays an average imperceptibility of 52.48 dB. For the threshold value of 0.3, it does an excellent job of achieving good balance between robustness and imperceptibility. Except for the gaussian noise, rotation, and average filtering attacks, it also demonstrates good robustness against common image attacks. The results of the experiment demonstrate that the suggested watermarking method outperforms competing methods.

Manoj kumar pandey

The purpose of this research was to investigate the relationship between affective tendencies in embarrassing situations and cheating behavior in a sample of adolescents. Two objectives were addressed: first, exploring the relationship between cheating behavior and shame-proneness, guilt-proneness, externalization, and detachment; second, analyzing the mediating role of detachment in the relationship between externalization and cheating behavior. The results showed positive correlations between the cheating behavior and externalization and detachment, a negative correlation with guilt, and no relation with shame. It was confirmed the mediating role of detachment. Implications for educators were discussed, emphasizing the importance of stimulation of students’ moral rules understanding.

Elena stănculescu

Objectives: Improper and inappropriate use of antibiotics is one of the possible factors affecting the transmission of antibiotic resistance is Because Pseudomonas aeruginosa is one of the most serious pathogenic bacteria in hospital environments and resistant It is an antibiotic that causes problems in treatment. This study aims to determine multiple resistances Pseudomonas has been treated with antibiotics, arsenic and metals. Materials and Methods: In this study, 23 strains of Pseudomonas aeruginosa were isolated from clinical specimens. for review Resistance of these bacteria to penicillin antibiotics was used by Kirby-Bauer method. The minimum concentration C.I.M. (and minimum lethal concentrations (C.B.M.) of antibiotics and heavy metals (cadmium, mercury) and arsenate Tubal dilution, agar and growth were performed in agar plate, respectively. Results: In this study, the highest and lowest MIC values obtained in Pseudomonas aeruginosa for metals, respectively. * 8 and 3 cadmiums (0.6 and 4.9 μg / ml), mercury (<0.12 and 4 μg / ml) and arsenate (10 × were 256 μg / ml). Of 23 strains, 84% to the antibiotic carbonicillin, 63% to piperacillin and 100% to 103 Arsenic and cadmium were resistant. Also, 82.6% of the strains were resistant to mercury. Conclusion: The results of this study showed that Pseudomonas aeruginosa strains have multiple resistance to arsenic, metals and the antibiotics are car penicillin and piperacillin.

Amirhossein jahromi

Abstract: This study was conducted on two groups of broiler , the first consists of 4 replicates of 10 birds and the second of 10 birds as each bird is a replicate in individual cages. The first group were reared on floor during the entire period ,while the second was reared in cages during the period from 2-7 weeks of age. All birds received the same ration with 2859 Kcal/ kg ME and 22% CP as a starter ration, 2995 Kcal/kg ME and 19.19% CP as a finisher ration. The results showed that cage birds had a significantly (P≤0.01) higher body weight , total and daily weight gain at all ages , significantly(P≤0.01) higher total and daily feed and protein consumption , at 2- 4 , 0-4 weeks , feed and protein conversion ratio at 4- 7, 0- 7 weeks. Also cage birds showed a significantly better growth rate at 2- 4 , 0- 7 weeks and less dressing percentage, higher wing percentage while other carcass parts did not differ significantly. The cage birds showed better economic efficiency by 27% comparing to floor birds.

Rafea mohammedtaher khulel

This study sets out to explore the Critical Success Factors (CSFs) necessary for Total Quality Management (TQM) implementation in hotels. It also aims to classify participating hotels into groups based on their TQM adoption by using cluster analysis. A quantitative survey method was applied. Data were collected from a sample of managers from four- and five-star hotels in Jordan, 170 questionnaires were distributed to managers and 104 usable questionnaires were returned. The findings revealed that TQM is existed and implemented in the hotel industry. The researcher then confirmed that four- and five-star hotels can be classified into two groups, namely, “high TQM adopters” and “low TQM adopters”.

Mukhles m. al-ababneh

Bauhinia racemosa Lam. is a tall tree growing throughout Sri Lanka, China, India, and Pakistan. Various parts of the plant have great medicinal potential in folklore medicine and are used for diarrhoea, fever, skin diseases, cough, malaria, etc. Analgesic, anti-inflammatory, antipyretic, antispasmodic, antiulcer, cytotoxicity and hypotensive activities of Bauhinia racemosa have been reported. Different parts of this plant contain β-amyrin, β-sitosterol, kaempferol, quercetin, scopoletin, scopolin and tannins

Dr. salman ahmed

Poor water quality and lack of access to improved sanitation continue to pose a significant threat to human health. The burden of disease analysis suggests that lack of access to safe water supply, sanitation and hygiene is the third most significant risk factor for poor health in developing countries with high mortality rates. Diarrhoea is the leading disease associated with unsafe water supply, sanitation and hygiene and is responsible for the deaths. The study observed that out of the 150 respondents, 37% are 31-40 years, followed by 20-30 years with 32%. 130 (86.7%) respondents have got married, and 61% of the respondents are female. 85% adopted the nuclear family system, and 50% of respondents are illiterates in the study areas. 85% of respondents are daily wage earners, 37% are earnings rupees between 2000-2500 per month. 27% of respondents are landless labours, and 37% of households possess below 2 acres of land. 40% of respondents suffer from health problems, and 44% consume rice as their staple food. 62% of respondents have debts, and 33% got from money lenders. 62% of respondents do not have toilet facilities and go open defecation. 92% of respondents stated that toilet makes dignity, saves time and energy, saves their children school days, makes adolescent girls privacy, save wage loss, and toilet makes quality life.

B suresh lal

The aim of this work was to prepare chitosan nanoparticles loaded with antineoplastic drug Lomustine (LCNPs), by ionic-gelation method with homogenization. The nanoparticles were characterized for particle size, polydispersity index (PDI), surface morphology, encapsulation efficiency, in-vitro drug release and cytotoxicity on human lung cancer cell line L132 by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The particle size, zeta potential and encapsulation efficiency of prepared nanoparticles ranged from 75±1.1 to 637±1.6 nm (PDI from 0.05±0.001 to 0.18±0.007), 37.2±0.21 to 53.8±0.18 mV and 66.74±1.4 to 98.0±1.8% re- spectively. The particles were spherical in shape with smooth surface in scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images. Mechanical shearing by homogenization treatment significantly changed the nanoparticle size. The drug release rate was biphasic and diffusion controlled over the 8 h. LCNPs greatly inhibited the growth of the L132 cancer cell line used in this study in comparison to the native Lomustine (LMT).

Archana mehrotra

Breast cancer commonly metastasizes to the bones, liver, lungs, and brain. However, metastasis to endocrine glands, particularly the adrenal and pituitary glands, is rare. We report the case of a 54-year-old woman with hormone receptor–positive, HER2-negative invasive ductal carcinoma of the right breast who initially showed a favorable response to standard therapy. Surveillance imaging in late 2022 revealed a left adrenal mass, subsequently confirmed as metastatic breast carcinoma. Following laparoscopic adrenalectomy, she developed primary adrenal insufficiency. By mid-2023, she presented with pituitary metastases, resulting in hypopituitarism, diabetes insipidus, and severe visual impairment. Despite targeted radiosurgery, her disease progressed rapidly, and she died in December 2024. This case illustrates an unusual metastatic pattern involving both the adrenal and pituitary glands and demonstrates the potential for aggressive clinical behavior even in hormone receptor–positive breast cancer. Clinicians should maintain a high index of suspicion for atypical metastatic sites to ensure timely diagnosis and optimize palliative care strategies.

Karishma

India’s automobile industry is the fourth largest automobile industry in the world. The researcher selected the automobile companies of 2 and 3 wheelers based on group A companies listed in the Bombay Stock Exchange. The selected automobile companies are Bajaj Auto ltd, Eicher Motors ltd, Hero MotoCorp ltd and TVS Motor Company ltd. The main target of this analysis is to compare the financial positions of the selected automobile companies for the time of a long time from 2016-2020. This study proved that financial position of Eicher Motors ltd financial position is superior to other selected automobile companies. Current ratio, quick ratio, debt-equity ratio, net profit ratio, return on assets ratio of Eicher Motors ltd is better than other selected automobile companies.

Dr. jeyalakshmi p

Self-concept and adjustments are important determinants of personality development of an individual and a conducive school environment can contribute building positive self-concept and making adjustment. This study attempted to investigate the level of self-concept and adjustment of visually impaired students attending special and inclusive school settings. Descriptive survey method was adopted to carry out this study and 165 visually impaired students studying in special and inclusive school settings located in Delhi and NCR participated as respondents for the study. The data gathering instruments used for this study include ‘Information Schedule’ designed by the researcher, Self-Concept Questionnaire (SCQ) by Sarswat and Adjustment Inventory for School Students (AISS) by Sinha and Singh. Data were analysed by applying statistical techniques namely– Percentage analysis, Mean, S.D. and t-test. Findings of the study indicated that visually impaired students in inclusive setting possess higher positive self-concept and demonstrate better adjustment than their counterpart in special school setting. Educational implications for different stakeholders are discussed.

Rubul kalita

A new reliable high throughput NOC router design is proposed with FSM based smart arbiter module for 4X4 Mesh architecture. This design is based the XY routing algorithm with prioritized round robin arbitration and synthesis of the proposed design is done on Spartan III FPGA. An enhanced work is also done in this paper to explore the drawbacks of the exceptional techniques of the existing generation and to research the scope for overall performance improvisation of the NoC designing

Trupti patil