Background: Prescribing patterns in systemic hypertension vary from place to place. Studies have shown that cost could be one of the factors responsible for non-adherence to treatment among hypertensive patients. Nigerian pharmacoeconomics studies have not provided a general guide on cost-effective prescribing for hypertensive patients in the country. The aim of the study was to examine the prescribing patterns, do cost effectiveness and cost minimisation analyses of the commonly prescribed antihypertensives, and determine if cost is a major reason many of the hypertensive patients of the District Hospital are usually lost to follow up. Methods: 5267 adult (≥18 years) non-antenatal patients’ cards of 2016 were reviewed for hypertension. Examination of the prescriptions, cost-effectiveness and cost-minimisation analyses of the commonly prescribed antihypertensives were done. Results: 12.6% of the patients were hypertensive. 73% of these hypertensive patients were treated pharmacologically. 40.8% adhered to treatment. 73% of the adherent ones responded to treatment. Amlodipine was the most expensive prescribed antihypertensive (N22). Amiloride-hydrochlorothiazide with the largest cost effectiveness ratio (CER) (9) was the most cost effective of all the combinations. Lisinopril- hydrochlorothiazide (N17) was preferable to the triple combination of lisinopril-amlodipine-hydrochlorothiazide (N39), and amlodipine-hydrochlorothiazide (N32) in cost minimisation. Conclusions: Cost of drugs probably had played a significant role in non-adherence to treatment among hypertensive patients in the District Hospital in 2016, since moduretic with the largest CER (9) and nifedipine with the greatest BP reduction when combined with hydrochlorothiazide (56/22 mm Hg) were rarely prescribed.

Emmanuel umegbolu

Arenaria serpyllifolia L. is a medicinally important plant found in subtropical and temperate regions of the Himalayas from Nepal to Kashmir. The plant is used traditionally to treat kidney and bladder-related problems. Flavonoids and xanthone-containing compounds, such as epicatechin, japonicumone, quercetin, etc, are reported in the plants. Plants have shown Inhibitory effects on Carboxyl esterase

Dr. salman ahmed

A web-based academic advising system was designed to facilitate more accurate advising sessions on campus, as well as provide a complete history of past advising sessions. Advisors may select which courses they wish a student to register in, up to several semesters into the future, as well as leave comments for the student and other campus staff. The system was designed and developed using Relational Data Model (RDM) and Data Flow Diagram (DFD) and was implemented using PHP and MySQL programming languages. The researchers have developed an interactive web-based information system that can help Nigerian universities to facilitate more accurate advising sessions on campus and make important decisions. The developed System can handle errors, updates and modification of data more efficiently and can be accessed anywhere and anytime than the manual methods of academic advising system. This paper describes an Advisement System designed to mitigate the issues of an out-of-the-box implementation in a Nigerian university to help improve retention and graduation. Successful implementation of this research study would enable the main objective of this system to assist Nigerian universities orientation camp in solving the problems associated with the manual method of the academic advising system

Ogala justin onyarin

Étudier les phénomènes grammaticaux actuels sans s’interroger sur la longue trajectoire historique qui a servi de support et de canal au français moderne manquerait de pertinence. En effet, une telle étude permet une meilleure compréhension des phénomènes linguistiques contemporains. Ainsi, notre domaine de recherche, la linguistique diachronique, met l’accent sur les connaissances étymologiques de la langue. Il s’agira, pour les besoins de l’article, de rendre compte de l’évolution morphologique du présent de l’indicatif depuis le latin jusqu’au français moderne. Notre curiosité nous poussera à nous interroger sur les raisons qui expliquent l’écart morphologique du présent de l’indicatif entre le latin et le français moderne. En sus, l’étude des variations diachroniques du présent de l’indicatif renseigne sur les formes actuelles de ce temps verbal. Du latin au français moderne, le présent de l’indicatif subit des flottements aussi bien dans ses radicaux que dans ses désinences. Ceci met en chef l’écart formel existant entre le présent latin et celui du français actuel. Toutefois, les phonèmes subirent des transformations selon qu’ils étaient toniques ou atones, radicaux ou désinentiels. Certaines formes se sont maintenues avec modification ou non de sons; d’autres ont complètement disparues du système. Suivant un ordre chronologique et des lois phonétiques cohérentes, nous montrerons que les formes actuelles du temps le plus usuel du système, le présent, ne sont pas le fruit du hasard. De ce fait, la langue moderne gagnerait à revisiter la morphologie des temps verbaux depuis leur origine pour mieux asseoir les difficultés liées à la conjugaison et fournir une explication authentique sur les variations de forme jusque-là ignorées par certains.

Assanvo

Cet article montre l’analyse des erreurs dans l’enseignement/apprentissage du Français Langue Étrangère au Ghana. Il a pour objectif principal d’analyser les erreurs commises en production écrite par les étudiants de Français Langue Étrangère (FLE) à l’Université du Ghana. Le corpus a été constitué du lexique de 100 apprenants. Les instruments de collecte des données ont été les questionnaires et les rédactions/compositions. Ces derniers ont été rédigés par les étudiants des niveaux 300 et 400. Etant donné la nature de l’étude, l’approche quantitative et l’approche qualitative ont été utilisées comme mode d’investigation. L’approche qualitative porte sur le modèle de l’analyse des erreurs proposé par Corder (1967) et l’approche quantitative met en évidence des données observables et quantifiables. Les principales erreurs rencontrées dans les productions écrites des étudiants ont été celles de la morphosyntaxe. Ces erreurs commises ont été analysés. Les recommandations de notre étude ont pour but d’améliorer la production écrite en Français Langue Étrangère.

Assanvo

In the present study the effect of the ethanol extract of Culcasia falcifolia on the neurotransmitter levels were evaluated. Pentylenetetrazole (PTZ) (60 mg/kg body weight, i. p) was administered to all the groups of mice to induce convulsions. After observing the convulsion, all groups rats were sacrificed, whole brain was dissected out and separated the forebrain. The brain tissue was homogenized and then centrifuged. The aqueous phase was taken for the assay. The reading was obtained using spectroflurimeter. The result of the present study shows that the ethanol extract of Culcasia falcifolia at the dose of 200 and 400 mg/kg body weight significantly increased the level of inhibitory neurotransmitter GABA and also showed significant increase in the levels of dopamine, noradrenalin and serotonin when compared to seizure control group (PTZ treated group) and was almost equivalent to control group. The findings of the study showed that the extract at 200 and 400 mg/kg body weight significantly (p<0.001) increased the levels of GABA, dopamine, serotonin and noradrenaline. The ethanol extract of Culcasia falcifolia exerted antiepileptic activity by decreasing seizure susceptibility to pentylenetetrazole-induced seizure in mice due to restoration of GABA, serotonin, dopamine and noradrenaline concentration levels in mice brain.

Gracelyn portia

Pada awal terjadinya pandemi COVID 19, telah terjadi banyak hal yang mengakibatkan perubahan di tengah masyarakat. Salah satunya adalah di kegiatan belajar mengajar. Berangkat dari hal tersebut maka pada pertengahan Agustus 2020 dimulailah satu kegiatan untuk membantu para guru yang ada di daerah untuk bisa beradaptasi dengan perubahan terkait kegiatan belajar mengajar pada masa pandemi. Kegiatan ini dilaksanakan dalam beberapa bulan dengan dua kegiatan utama dilaksanakan secara daring dan kegiatan pendampingan juga secara daring. Pada April 2021 didapatkanlah hasil dari kegiatan ini yang sebagian besar menilai kegiatan positif dan membantu dalam aplikasi kegiatan belajar mengajar. Hanya saja yang disayangkan kegiatan ini tidak menjangkau banyak peserta.

L

The decision of the government of India to allow foreign direct investment in higher education is based on a consultation paper prepared by the commerce ministry, which is marked by arguments, perverse logic and forced conclusions. FDI in any field does not have an attached objective of fulfilling social agenda of the welfare state. It is guided by profit and market. This would result in commoditization of education. As per past most foreign institutes invest in technical courses which market needs rather than in quality education and research which is important for creating and developing human resource. There is a shortage of funds in higher education sector. Here are not many ways in which this investment in this sector can be increased in this sector domestically. Since a large number of students go abroad for their higher education, it is sensible to allow foreign universities to set up their campuses here, in India. This would help in arresting the outflow of monetary and human capital. Further, foreign higher educational institutes would create competition with the local institutes making them internationally competitive this article examines the issues and financial compulsions, presented in the consultation paper

Dr gedam kamalakar

Ethanol extracts of leaves, male flowers and fruit peel of Luffa cylindrica (L.) Roem., were evaluated for analgesic effect using the analgesy meter test, a mechanically induced pain model. Extracts at 500 mg/kg, p.o., were tested and compared with diclofenac sodium 50mg/kg as a standard analgesic drug. The mechanical force was applied to the rat's paw and continuously increased. The point at which the rat can’t bear further pressure and starts to struggle to free the paw was taken as a nociceptive response. Readings were taken before and after 1, 2 and 3hr following drug administration. The analgesic response was continuously increasing till 3hrs. Tested extracts produced significant and comparable analgesic effects as with diclofenac sodium.

Dr. salman ahmed

In this paper, investigations are made to analyze the human body temperature during wound healing process due to surgery. Wound is considered after the skin graft. Skin graft is a technique used in plastic surgery. Skin is the first line of defense between the human and environment, it is very susceptible to damage. Internal body or core temperature (Tb) is one of the clinical vital signs along with pulse and respiratory rates. Any disturbance in body temperature will drive complexities in wound healing process. These studies are important in the mechanism of establishing the limits of thermal regulation of human body during the healing process in different situations and conditions. The Finite element method is used to analyze tissues temperature for normal tissues (donor site) and abnormal tissues (tissues after surgery). Appropriate boundary conditions have been framed. Numerical results are obtained using Crank Nicolson Method.

Manisha jain

Geotextiles have been successfully used for reinforcement of soils to improve the bearing capacity. In this study geotextile as a tensional material have been used for reinforcement of granular soils. Laboratory California Bearing Ratio (CBR) tests were performed to investigate the load-penetration behavior of reinforced soils with geotextile. Samples of granular soil are selected and tested without reinforcement. Then CBR tests were performed by placing geotextile in one or two layers at various depths in soil sample. The effect of the number of geotextile on the increase in bearing capacity of reinforced granular soil is discussed.

Mayura

Background and Objective: Health care workers (HCWs) are at the highest risk of contracting COVID-19, so their knowledge about the disease and their preventive attitude and practice toward COVID-19 are of concern. The present study aimed to assess the knowledge, attitudes, and practices of HCWs toward COVID-19 in Al-Thawra Hospital, Ibb Governorate, Yemen. Materials and Methods: We conducted a cross-sectional survey among HCWs in Al-Thawra Hospital, Ibb, Yemen, from January 1 to March 31, 2022. Results: Of the 80 participants, 50 (62.5%) were males and 30 (37.5%) were females with a mean age of 29.33±7.86 years. About 51.2% of respondents were aware that sneezing is a recognized symptom of COVID-19, while most were unaware of the extrarespiratory symptoms of the disease, such as diarrhea and confusion. About 28.7% of respondents believed that eating or contacting wild animals would result in infection by the COVID-19 virus, with the majority (71.3%) agreeing that wearing a well-fitting face mask effectively prevents COVID-19 infection. Approximately 48 respondents (60.0%) believed that washing hands could prevent contracting COVID-19, and only 31 (38.7%) agreed that if a patient shows signs and symptoms of COVID-19, they can confidently participate in that patient’s treatment. In response to avoid COVID-19, about 23 respondents (28.7%) had always gone to crowded places, and 35 (43.6%) had always worn face masks at every contact with patients, while only 14 (17.5%) of participants refrained from shaking hands and 37 (46.3%) always washed their hands before and after handling each patient. Conclusion: This study showed that most respondents have poor knowledge regarding the clinical picture of COVID-19 and its mode of transmission as most of them failed to detect an extrapulmonary manifestation of COVID-19 and were unaware of the possibility of transmission of the disease from wildlife. In addition, the attitude and preventive practice of the respondents were unsatisfactory in containing the transmission of the disease.

Karishma

Purpose: With an increase in updated technologies use of Fintech services have also been increased. Intention to use of Fintech services largely depend upon attitude of individuals towards adoption of these services. Drawing upon the Technology Innovation Model (TAM) theory this paper observes different factors associated with customer’s attitude towards acceptance of fintech facilities provided by banks that in turn affect intent about usage of these services. The features like Supposed Utility, Apparent Comfort for Usage, Supposed Peril, Trust Factor, Administration Sustenance, Consumer Innovativeness, Attitudes in the direction of Acceptance, Intent in the direction of Adoption are used in this study. Methodology: The data was collected from residents of Delhi using a survey method through online mode. A well-structured questionnaire was circulated among customers with the help of employees of each branch by using the online platform WeChat. Also, Questionnaire was circulated among customers with the help of employees of each branch who gave them proper instructions to fill the questionnaire. It was circulated through WeChat. To inspect the strength of the association amid factors, , Confirmatory Factory Analysis (CFA) and regression path analysis were applied using SEM in AMOS software. Findings: The findings revealed that Government Support is a key predictive variable for the adoption of Fintech services. Whereas Perceived Ease of Use and Perceived Risk are not significantly supported the attitude towards adoption of Fintech services. While other factors slightly supported attitude towards adoption. Practical Implications: The findings of this article are useful for banks to provide empirical framework for customers to adopt new, user-centered fintech services. Originality/Value: This article in useful for the banking institutions, Government agencies and insurance companies provide empirical framework for customers to adopt new, user-centered fintech services.

Nandini jagannarayan

The coexistence of Moyamoya syndrome (MMS) and Graves’ disease (GD) is uncommon. Here, we report a case of a 41-year-old Filipino female, who presented with thyrotoxicosis and acute ischemic stroke. Based on her clinical presentation, cerebral computed tomography angiography, and thyroid function tests, she was diagnosed with MMS and GD. Her Burch-Wartofsky point scale score was 30, suggesting an impending thyroid storm. Antithyroid therapy was started with her neurological status deterioration initially, but after controlling the thyroid storm, the patient’s neurological status stabilized. She remained stable till she travelled to her country. We hypothesized that MMS in a patient with GD is mediated through anti-dsDNA antibodies, by altering key biological mechanisms, that is, inflammation, neutrophil extracellular traps, and apoptosis that drive a distinctive and coordinated immune and vascular activation. To the best of our knowledge, this is the first case of MMS associated with GD reported in Qatar.

Karishma

Experimental and numerical investigation have been done to evaluate the aluminum agglomerate size in AP/HTPB/Aluminum propellants and compared it with burning rate results. Bimodal AP particle size distribution is considered in the present work. The effect of aluminum size, aluminum content, fine AP size, fine AP/binder ratio and coarse AP size in aluminum ignition, accumulation and agglomerate formation during combustion, typically in their ranges, are focused. The burning rates were found to be higher for the propellants with lower fine AP/binder ratio. The agglomerate sizes for the propellants with 10 % Al was found to be higher than those with 15 and 18 % aluminum. Observing the agglomerate sizes and the burning rate trends, it can be concluded that the agglomerate sizes vary inversely as the burning rates.

Boopathy govindarajan

The Art of Public Speaking BY J. BERG ESENWEIN AUTHOR OF "HOW TO ATTRACT AND HOLD AN AUDIENCE," "WRITING THE SHORT-STORY," "WRITING THE PHOTOPLAY," ETC., ETC., AND DALE CARNAGEY PROFESSOR OF PUBLIC SPEAKING, BALTIMORE SCHOOL OF COMMERCE AND FINANCE; INSTRUCTOR IN PUBLIC SPEAKING, Y.M.C.A. SCHOOLS, NEW YORK, BROOKLYN, BALTIMORE, AND PHILADELPHIA, AND THE NEW YORK CITY CHAPTER, AMERICAN The Art of Public Speaking by Dale Carnagey (AKA Dale Carnegie) and J. Berg Esenwein 2 INSTITUTE OF BANKING THE WRITER'S LIBRARY EDITED BY J. BERG ESENWEIN THE HOME CORRESPONDENCE SCHOOL SPRINGFIELD, MASS. PUBLISHERS Copyright 1915 THE HOME CORRESPONDENCE SCHOOL ALL RIGHTS RESERVED TO F. ARTHUR METCALF FELLOW-WORKER AND FRIEND Table of Contents Page THINGS TO THINK OF FIRST--A FOREWORD IX CHAPTER I --ACQUIRING CONFIDENCE BEFORE AN AUDIENCE 1 CHAPTER II --THE SIN OF MONOTONY 10 CHAPTER III --EFFICIENCY THROUGH EMPHASIS AND SUBORDINATION 16 CHAPTER IV --EFFICIENCY THROUGH CHANGE OF PITCH 27 CHAPTER V --EFFICIENCY THROUGH CHANGE OF PACE 39 CHAPTER VI --PAUSE AND POWER 55 CHAPTER VII --EFFICIENCY THROUGH INFLECTION 69 CHAPTER VIII --CONCENTRATION IN DELIVERY 80 CHAPTER IX --FORCE 87 The Art of Public Speaking by Dale Carnagey (AKA Dale Carnegie) and J. Berg Esenwein 3 CHAPTER X --FEELING AND ENTHUSIASM 101 CHAPTER XI --FLUENCY THROUGH PREPARATION 115 CHAPTER XII --THE VOICE 125 CHAPTER XIII --VOICE CHARM 134 CHAPTER XIV --DISTINCTNESS AND PRECISION OF UTTERANCE 146 CHAPTER XV --THE TRUTH ABOUT GESTURE 156 CHAPTER XVI --METHODS OF DELIVERY 171 CHAPTER XVII --THOUGHT AND RESERVE POWER 184 CHAPTER XVIII --SUBJECT AND PREPARATION 199 CHAPTER XIX --INFLUENCING BY EXPOSITION 218 CHAPTER XX --INFLUENCING BY DESCRIPTION 231 CHAPTER XXI --INFLUENCING BY NARRATION 249 CHAPTER XXII --INFLUENCING BY SUGGESTION 262 CHAPTER XXIII --INFLUENCING BY ARGUMENT 280 CHAPTER XXIV --INFLUENCING BY PERSUASION 295 CHAPTER XXV --INFLUENCING THE CROWD 308 CHAPTER XXVI --RIDING THE WINGED HORSE 321 CHAPTER XXVII The Art of Public Speaking by Dale Carnagey (AKA Dale Carnegie) and J. Berg Esenwein 4 --GROWING A VOCABULARY 334 CHAPTER XXVIII --MEMORY TRAINING 343 CHAPTER XXIX --RIGHT THINKING AND PERSONALITY 355 CHAPTER XXX --AFTER-DINNER AND OTHER OCCASIONAL SPEAKING 362 CHAPTER XXXI --MAKING CONVERSATION EFFECTIVE 372 APPENDIX A--FIFTY QUESTIONS FOR DEBATE 379 APPENDIX B--THIRTY THEMES FOR SPEECHES, WITH SOURCE-REFERENCES 383 APPENDIX C--SUGGESTIVE SUBJECTS FOR SPEECHES; HINTS FOR TREATMENT 386 APPENDIX D--SPEECHES FOR STUDY AND PRACTISE 394 GENERAL INDEX 506

Kamal singh

The emergence of big data has caused various challenges to data management lifecycle including storage, processing, sharing, and applications. During the same time frame, the fast development in cloud computing provides increased efficiency in computing support that address these challenges. However, there are issues in big data and cloud computing management which include security concerns, data fragmented, and distrust in using clouds that could become the roadblock to e-government services success. Although ensuring data management has been the responsibility of providers in the public sector, this issue seems to be unavoidable. In such circumstances, initiatives from the public sector agencies are crucial to ensure data is effectively managed. This research in progress aims to investigate how the public sector agencies in Terengganu manage data to improve the e-government performance. The research uses the interpretive research paradigm and adopts the qualitative research methodology using a case study design. A single case of a public sector which utilizes big data and cloud computing within the e-government platform is selected as the case for this research. The findings of this research are expected to be used in developing a framework of big data and cloud computing management which will assist in providing reliable and accurate information to citizens within the e-government environment.

Asyraf afthanorhan

The National Education Policy 2020 (NEP 2020) aims to modernize India's higher education system by prioritizing the learner, increasing accessibility, and fostering inclusivity. It emphasizes the importance of libraries as information hubs and libraries, with the policy focusing on their resources and facilities. The policy requires sufficient library employees to manage facilities, create suitable career courses, and foster cooperation between educational institutions and libraries. Infrastructures for libraries are crucial for adult education, lifelong learning, and study. Schools, school complexes, and public library locations should be well-designed and equipped with information and communication technology. Central and state governments are responsible for creating and funding libraries, ensuring they are available and reasonably priced for everyone in the nation. Digital libraries and online resources are included in the NEP 2020, with efforts to improve accessibility online and expand the reach of digital libraries. The policy also includes provisions for enhancing all current libraries, establishing reading rooms and rural libraries in underprivileged areas, making reading materials in Indian languages widely accessible, opening child-friendly and transportable libraries, creating social literary societies, and promoting better partnerships between educational institutions and libraries. The government is focusing on providing top-notch online resources for education, including digital resources, online courses, applications, satellite TV channels, online books, and IT-equipped libraries and Adult Education Centers across India. The policy has significantly raised the standard of instruction in India's higher education establishments, providing students with a more comprehensive and holistic education. Preliminary findings suggest that the policy has had positive effects, but significant human, material, and technological resources are needed for its success. The policy also seeks to increase diversity in higher education by providing financial aid and scholarships to underrepresented groups.

Dr. awadhesh singh gautam

Scholars who apply artificial intelligence to political questions seek, most generally, to expand the scope and relevance of political model analysis. By incorporating the effects of variable human notions, traditions, and meanings, they seek to humanize political models. Most early applications of artificial intelligence in political science research address substantive issues pertaining to political decision making. Most of these works apply production-system technology to construct choice models in for eign-policy decision contexts. In recent years, political applications have begun to diver sify. Today, lively research efforts flourish in widely varied application areas, such as computational text analysis, logic programming, computer learning, and conflict sim ulation. The works reviewed here constitute the early steps of a nascent program of study. Much remains to be accomplished. Nevertheless, the efforts conducted thus far suggest many potentially fruitful research avenues. Youth are the most essential and promising segment of every country’s population. India has a larger advantage over other countries in terms of becoming a global leader because we effectively tap into the youth’s potential. Quality education is the only way to achieve this. With artificial intelligence’s potential growth in India, now is the ideal time to incorporate AI in education to reap its benefits and prepare India’s young for the future. Artificial intelligence has great potential in India. India’s AI technology has the potential to make it a world leader in artificial intelligence. In India, AI technology is used effectively in nearly every area, including agriculture, healthcare, education, infrastructure, transportation, retail, manufacturing, and

Dr gedam kamalakar

Library automation is just not a book inventory where hold, issue and receiving of books by using technological tools and services. Our applied research was found that most of the library administrative functionalities such as ‘Acquisition and Accessioning’, ‘auto Indexing & Classification’ and auto Cataloging (Books & Non books materials)’, inventory with real-time OPAC facilities and many more library science concepts are still missing constructs in Universities/College libraries across the country. In this modern era the concept of eLibrary is more popular because availability and accessibility of digitized content sharing through IT/ICT infrastructure is huge. During our research we found that cognizance of Library automation was completely ignored and focused on only talking and establishment of eLibrary. As we all know that “Physical Library” is not a substitute for “eLibrary”. In fact eLibrary is part of a Physical Library to share authenticated digitized content through IT/ICT infrastructure. After a decade of our applied research in the area of Library science, eventually we recorded a lot of findings based on our survey and discussion with senior researchers and Librarians. Our serious and consistent effort makes to succeeds in designing comprehensively effective and efficient operational strategies to build a “world class Library Automation and Paper less Library Management System” for Universities/College libraries. This paper emphasizes about the comprehensive real-time architecture and operational modules and their effectiveness to achieve the user’s satisfaction (flow of functionalities as per the exact need of the Library Management system). This dealt with how emerging technological tools and services are effectively integrated for designing new strategies in the area of library science includes various automation process and security concepts (using Barcode/RFID). Eventually, our dream comes true in building Use of Emerging Technological Tools and Services to building world class Paper less Library Information &Management System [LIMS]. presently deployed and use of this software product in more than 300 satisfied and client locations in INDIA, this product popularly named as “eLib” by AarGees Business Solution, Hubli, India. Though, our research is still on and continuing for further development to build “Global knowledge sharing Centre”.

Dr. chandrashekhar uppin