Screening and selection of potential beneficial rhizosphere fungi from medicinally important plant species in tamil nadu, india,

The problem of chemical fertilizers and pesticides can be solved by the action of plant growth promoting fungi (PGPF). The indigenous fungal isolates obtained from the rhizosphere soil can be used as they are said to solubilize the insoluble zinc, phosphorous, potassium etc. They are known to control the different fungal pathogens and thus promoting the plant growth and health. In the present study, attempt was made to isolate soil beneficial fungi from the rhizosphere soil samples of important medicinal plants such as Aegle marmelos, Azardirachta indica and Citrus limon. A total of 22 fungal isolates was isolated and screened for their efficacy on phosphate and zinc solubilization and antagonistic potential against selected plant pathogenic fungi under in vitro condition and the isolates were identified up to species level.

Dr. SARANYA DEVI K Dr. saranya devi k

Enhancing the art of conducting medical ward rounds: addressing deficiencies and achieving excellence

Background: Ward rounds are a cornerstone of inpatient care, critical to patient management, interdisciplinary communication, and bedside teaching. However, despite their importance, ward rounds are often unstructured and inconsistent, limiting both clinical efficiency and educational impact. Objective: This narrative review examines common deficiencies in current ward round practices and proposes a structured, evidence-informed framework to enhance their effectiveness. Methods: A narrative review was conducted to identify deficiencies in ward round practices and develop a practical, evidence-informed framework for improvement. Given the focus on conceptual and experiential insights, a formal quality appraisal of the included studies was not performed. Results: The review identified recurrent challenges, including poor planning, unclear leadership, inadequate time management, and a lack of integrated teaching. Drawing on best practices, a three-phase model—preparation, execution, and education—is proposed to enhance team communication, patient involvement, and trainee learning. Conclusions: Structured, goal-oriented ward rounds can significantly improve care coordination, safety, and clinical education. Institutions should prioritize standardized ward round models supported by training in leadership, teaching, and interdisciplinary collaboration.

Karishma Karishma

1. critical study of guggulu kalpana with special reference of bhaishajya ratnavali

Bhaishajya kalpana is an art and science of preparing and dispencing medicine. Guggulu is a Niryasa (oily latex) achieved from small tree called Indian bedellium. Botanical name is commiphora mukul. Guggulu is an amorphous, translucent, solid adhesive, oleo-gum resin is produced by the process of gummosis from its plant. Many other Ayurvedic classics have mentioned various formulations of Guggulu for the treatment of various ailments. Bhashajya ratnawali followed various kalpana use for formuations. Guggulu kalpana is secondary formulations of bhaishajya kalpana. . Guggulu is one among the best binding agents and its used as single or compound drug in the form of pills, Formulations which contains Guggulu as main ingredient, they can be called as Guggulu kalpana. Here in Bhaishajya Ratnawali, Guggulu is used in yoga for both purposes, as a base and as well as medicament also.In bhaishajya Ratnavali Guggulu when modified into different formulations. It can also be used in many diseases along with different combinations of drugs with their anupana, Guggulu kalpana beneficial in treating many diseases. The Guggulu Kalpana is indicated in almost all the strotovikaras and also a number of research works have been proved the wide range of action of Guggulu .

Suri abhiram

The impact of internal service quality on job satisfaction in the hotel industry

Service quality is a key factor for success in any hotel. Many researchers have conducted studies on service quality, but only a few studies have been conducted on internal service quality (ISQ) in general, and in the hotel industry in particular. Since there is no general agreement among researchers on the measurement of ISQ, many studies have used SERVQUAL instrument to measure the employees’ perceptions of ISQ. The purpose of this study is to explore the influence of ISQ on employee’s job satisfaction in five-star hotels in Jordan. The current study was carried out by measuring the data gathered through a seven-point Likert scale. The quantitative survey method was applied, and therefore the SERVQUAL instrument was used to measure ISQ, and the Job Satisfaction Survey (JSS) was used to measure job satisfaction. Data obtained from a sample of 238 respondents drawn from 14 five-star hotels in Jordan were analysed with the SPSS software based on descriptive statistics. The study’s findings indicated that the ISQ of five-star hotels in Jordan has a significantly positive influence on an employee’s job satisfaction. These findings support the hypothesis that there is a positive relationship between ISQ in the hotel industry and industry employees’ job satisfaction.

Mukhles m. al-ababneh

Sorghum bicolor-based supplement reduces oxidative stress and pro-inflammatory cytokines to mitigate rotenone-induced parkinsonian-like motor dysfunctions in rats

Parkinson’s disease is a common movement disorder associated primarily with oxidative stress-mediated degeneration of dopaminergic neurons. Earlier studies showed that Sorghum bicolor-based supplement (SbS) exhibited antioxidant and neuroprotective activities and might likely rescue the death of dopaminergic neurons in Parkinson’s disease. This study examined the effect of SbS on rotenone-induced Parkinsonian-like motor deficits in rats and the involvement of oxidative stress and pro-inflammatory cytokines. Rats were divided into six groups and treated orally with sunflower oil (vehicle-control), rotenone (2.5 mg/kg) alone or in combination with each dose of SbS (50, 100, and 200 mg/kg) and levodopa-carbidopa (10 mg/kg) on an alternate day for 28 days. The changes in motor functions were evaluated on day 28 and the brain concentrations of oxidative stress biomarkers and pro-inflammatory cytokines (tumor necrosis factor-alpha and interleukin-6) were determined. Rotenone caused motor deficits by impaired locomotor activity in the open field test and induced catalepsy in the bar test, which were attenuated by SbS. Rats pretreated with SbS had reduced brain levels of malondialdehyde, nitrite, and pro-inflammatory cytokines compared to rotenone controls. SbS mitigated rotenone-induced depletion of reduced glutathione and antioxidant enzymes in the rat brain. The results suggest that SbS ameliorated rotenone-induced Parkinsonian-like motor dysfunctions by reducing neuronal oxidative stress and pro-inflammatory cytokines in rats.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Lagrangian dynamics of particle transport in oral and nasal breathing

We present a large-eddy simulation (LES) of saliva particle transport during normal human breathing through the nose and mouth. The flow of the air–saliva mixture is modeled using an Eulerian LES that is coupled with a Lagrangian particle tracking module to obtain trajectories of saliva particles in a room with stagnant air conditions. The coupled Eulerian–Lagrangian simulation yields novel insights into the intricate dynamics of Lagrangian coherent structures (LCS) and fundamental material lines that emerge from the saliva particles' trajectories during several breathing cycles. Further, we systematically compare the quantitative LCS diagnostics of mouth breathing with those of mouth and nose normal breathing. Analyzing the simulation results of human breathing from the mouth and nose, we show that, soon after the first breathing cycle, saliva particles form a series of roll-up vortex rings that propagate forward. The forward propagation of these vortex rings leads to the formation of an asymmetrical primary forefront vortex. The individual vortex rings continuously propagate forward, merging with the forefront vortex, and ascending along the limb of the leading vortex.

Hossein Seyedzadeh Hossein seyedzadeh

N-gram-based machine learning approach for bot or human detection from text messages

Social bots are computer programs created for automating general human activities like the generation of messages. The rise of bots in social network platforms has led to malicious activities such as content pollution like spammers or malware dissemination of misinformation. Most of the researchers focused on detecting bot accounts in social media platforms to avoid the damages done to the opinions of users. In this work, n-gram based approach is proposed for a bot or human detection. The content-based features of character n-grams and word n-grams are used. The character and word n-grams are successfully proved in various authorship analysis tasks to improve accuracy. A huge number of n-grams is identified after applying different pre-processing techniques. The high dimensionality of features is reduced by using a feature selection technique of the Relevant Discrimination Criterion. The text is represented as vectors by using a reduced set of features. Different term weight measures are used in the experiment to compute the weight of n-grams features in the document vector representation. Two classification algorithms, Support Vector Machine, and Random Forest are used to train the model using document vectors. The proposed approach was applied to the dataset provided in PAN 2019 competition bot detection task. The Random Forest classifier obtained the best accuracy of 0.9456 for bot/human detection.

Chandra sekhar sanaboina

In-silico drug design, synthesis, characterization and biological evaluation of 2-azetidinone derivatives for antileukemic activity

2-Azetidinone shows biological activities like anti-bacterial, anti-microbial activity, anti-tubercular activity, and anti-cancer activity. 2-azetdinone derivatives were synthesized by simple procedures. The first step is synthesis of benzohydrazide through nucleophilic substitution reaction between methyl benzoate and hydrazine hydrate. The above formed compound is then treated with substituted aromatic aldehydes in the presence of catalytic amount of concentrated hydrochloric acid with stirring for one hour to give benzohydrazone which results in the formation of Schiff bases.Schiff bases undergone cyclisation in the presence of chloroacetylchloride and diethylenediamine by using ethanol as a solvent upon stirring for 4 hour’s yielded 2-azetidinone derivatives. The in-silico anti-leukemic activity was determined by using the computational tools i.e. “PASS Online”, “AutoDock4.2” and “ADMET” properties by online software’s. Among these six derivatives compounds (AZT-6) was shown more activity when compared with the other five compounds.

M. yaswanth

A systematic evaluation of research on social engineering attacks prevention

Social engineering is a method of information security that allows for system or network access. When victims are unaware of techniques, models, and frameworks to prevent them, social engineering attacks happen. In order to stop social engineering attacks, the current research describes user studies, constructs, assessment, concepts, frameworks, models, and techniques. Sadly, there isn't any specific prior research on mitigating social engineering attacks that thoroughly and efficiently analyzes it. Health campaigns, human security sensor frameworks, user-centric frameworks, and user vulnerability models are examples of current social engineering attack prevention techniques, models, and frameworks. Guidance is required to examine cybersecurity as super-recognizers, possibly acting as police for a secure system, for the human as a security sensor architecture. This research aims to critically and systematically analyze earlier material on social engineering attack prevention strategies, models, and frameworks. Based on Bryman & Bell's methodology for conducting literature reviews, we carried out a systematic review of the available research. Using a protocol, we discovered a novel strategy to stop social engineering assaults in addition to approaches, frameworks, models, and assessments, based on our review. We discovered that the protocol can successfully stop social engineering assaults, including health campaigns, the susceptibility of social engineering victims, and co-utile protocol, which can control information sharing on a social network. This comprehensive evaluation of the research is what we're presenting in order to suggest safeguards against social engineering assaults.

Mahesh Donga Mahesh donga

Matricaria chamomilla

A short review on the multi-use of this ancient herb, German Chamomille. Presented is a synthetic route to azulene, its most bioactive principle (antioxidant, disinfectant, wound-healing, antibacterial).

Stefan dahl

Analyse des erreurs dans la production écrite des étudiants de fle à l’université du ghana

Cet article montre l’analyse des erreurs dans l’enseignement/apprentissage du Français Langue Étrangère au Ghana. Il a pour objectif principal d’analyser les erreurs commises en production écrite par les étudiants de Français Langue Étrangère (FLE) à l’Université du Ghana. Le corpus a été constitué du lexique de 100 apprenants. Les instruments de collecte des données ont été les questionnaires et les rédactions/compositions. Ces derniers ont été rédigés par les étudiants des niveaux 300 et 400. Etant donné la nature de l’étude, l’approche quantitative et l’approche qualitative ont été utilisées comme mode d’investigation. L’approche qualitative porte sur le modèle de l’analyse des erreurs proposé par Corder (1967) et l’approche quantitative met en évidence des données observables et quantifiables. Les principales erreurs rencontrées dans les productions écrites des étudiants ont été celles de la morphosyntaxe. Ces erreurs commises ont été analysés. Les recommandations de notre étude ont pour but d’améliorer la production écrite en Français Langue Étrangère.

Assanvo

Dan-nucnet: a dual attention based framework for nuclei segmentation in cancer histology images under wild clinical conditions

Nuclei segmentation plays an essential role in histology analysis. The nuclei segmentation in histology images is challenging in variable conditions (clinical wild), such as poor staining quality, stain variability, tissue variability, and conditions having higher morphological variability. Recently, some deep learning models have been proposed for nuclei segmentation. However, these models rarely solve the problems mentioned above simultaneously. Most of the information in Hematoxylin and Eosin (H&E) stained histology images is in its channel, and the remaining information is in the spatial domain. We observed that most problems could be solved by considering channel and spatial features simultaneously, e.g., the spatial and channel features provide the solution to the morphological variability and staining variability, respectively. Therefore, we propose a novel spatial-channel attention-based modified UNet architecture with ResNet blocks in encoder layers. The UNet baseline preserves coarse and fine features, thus proving the solution to the tissue variability. The proposed method significantly improves the segmentation performance compared to the state-of-the-art methods on three different benchmark datasets. We demonstrate that the proposed model is generalized for 20 cancer sites, more than any reported literature. The proposed model is less complex than most state-of-the-art models. The impact of the proposed model is that it will help improve further procedures such as nuclei instance segmentation, nuclei classification, and cancer grading.

Ibtihaj Ahmad Ibtihaj ahmad

Low-impact exercises for improving symptoms in parkinson's disease: a literature review

Objective: This study fills an important research gap by focusing on the effectiveness of low-impact exercise in Parkinson's disease (PD), taking into account the different challenges faced by people with varying degrees of disease severity. Motivation: Unlike generic investigations into exercise and PD, our research prioritizes low-impact activities, considering safety concerns related to balance deficits and coordination challenges in the PD population. The study aligns with a patient-centred approach, aiming to provide a safer alternative to traditional exercise modalities. Approach: Conducting a comprehensive literature review, we conducted an online literature search on various databases, specifically investigating about low-impact exercises on both motor and non motor symptoms in PD individuals. Review process involved capturing diverse intervention types, durations, frequencies, and intensities. Findings: The amalgamation of diverse outcome measures, including UPDRS, Berg Balance Scale, TUG, 6MWT, and PDQ-39, showcased the multifaceted impact of low-impact exercises on both movement related and non-movement related symptoms. Notably, aerobic exercises being treadmill walking, cycling, and group sessions, emerged as pivotal interventions, demonstrating improvements in gait, balance, flexibility, and overall quality of life for PD individuals. Conclusion: While acknowledging limitations, such as potential publication bias and a focus on aerobic exercises, this study provides meaningful decision making information for clinicians and researchers. Future research should diversify interventions and methodologies to enhance the evidence base and address nuanced aspects of low-impact exercises in PD management. The results of this review contribute to the existing body of knowledge regarding the nuanced benefits of personalized low-impact exercise for Parkinson's disease.

Nagarjuna narayanasetti

A study on the impact of micro finance in empowerment of self-helpgroups’ women in visakhapatnam district

In olden days in most of the family male members were meant for earning income to the family where as the female members looked after the house works. In most of the family it was followed. After some time it was felt that if the female members are involved in some works other than the family affairs it would be the support extended by them to their spouse and family members. Therefore, in some family the female members were allowed to work in some industries and agriculture. Most of the women members supported to the family members the work or job involved by the male members of the family. Being India a country having more than 65 percent of its population are residing in rural areas. They depend only on agriculture and allied industries of agriculture. Due to the failure of rainfall and problems of insects and the monsoon nowadays the farmer could not earn even the amount incurred by them to cultivate the produces. But the necessity of the family is going on increasing day by day. Further, the prices of the domestic utilities are also increasing like anything. It is very difficult to run the family with single earning. Therefore, it is necessary for both the male and female members in the family to bring income to meet their requirements. In urban areas, there is more number of industries, which provide employment opportunities to both of the gender. However, if consider the position of the village women, they do not have much awareness on industrial work. Further, they have only limited literacy knowledge, which paved them to engage only in agriculture labour, which further made them weak in their financial position, as there is only limited scope for income in the agriculture work. Hence, most of the family in the rural parts of the country led a very poor life, which worsens the younger generation particularly in education. To minimize the unemployment problems in the rural areas and to generate the income to the family in the rural parts, the central government introduced Micro Finance to encourage the rural public to generate income to their family by way of doing small business or involved in some self-employment activities. As a part of the development of women in the rural areas, Self-help groups were established in the year 1993-94 in Uthrapradesh. But the evolution of SHGs commenced in 1990s. Micro finance plays vital role in the empowerment of women particularly in the village areas by providing financial assistance through self-help groups in the local areas since 1990. Andhra Pradesh government emphasizes more on the development of women through Self-help groups. The banks are given direction to provide more volume loan to the self-help groups. More number of self help groups was established in all villages. NGOs and government create awareness among all women in the rural areas to form self-group even for each line and street in all villages of Andhra Pradesh. We happened to see number of SHGs is being established and functioning well. The self-help group members are involved in various activities like running a canteen, manufacturing pickles and handy crafts and cloth items, etc. The local banks are adopting the particular villages for providing loan to self-help groups. Though the Micro finance extends maximum support to the development of women and the self help groups, the members in self-help groups have different views about micro finance and face many issues in getting the loan and the repayment of the loan. In many occasions, the members in self-help groups are compelled by family members not to involve in SHGs activities because of various reasons. In some of the SHGs the income level of the members is very low when compared with the income from other SHGs. What are the actual causes? What is the role of micro finance in empowerment of women? To know all these reasons a thorough study is to be undertaken.

Dr tatayya bommali

Acute systemic toxicity of four mimosaceous plants leaves in mice

Nature provides drugs in the form of medicinal plants to cure all ailments of mankind with fewer side effects. These medicinal plants can cause some serious damaging effects on the vital organs of the body too; there is a need of toxicity studies to provide their safe use both in human and animals. The present study reports the acute systemic toxicity of methanolic extracts of leaves of Adenanthera pavonina L., Peltophorum roxburghii Deneger., Prosopis cineraria Druce and Prosopis juliflora DC., (Mimosaceae) in swiss albino mice to explore their suitable doses for pharmacological screening. Observations were made immediately and after 1/2, 1, 4, 24 and 48hours of intraperitoneal drug administration. Adenanthera pavonina extract at the dose of 150 mg/kg body weight is considered to be safe. Whereas remaining extracts of investigated plants are relatively safe at the dose of 100 mg/kg body weight.

Dr. Salman Ahmed Dr. salman ahmed

Immunohistochemical expression of progesterone receptor and b-cell lymphoma-2 antigen in uterine leiomyomas in a southwestern nigerian teaching hospital

Background: Uterine leiomyoma is the most common benign smooth muscle tumor of unknown aetiology. Progesterone may contribute to leiomyoma growth through the induction of B-cell lymphoma-2 (BCL-2) protein in leiomyoma cells. This study aims to determine the patterns of Bcell lymphoma-2 (BCL-2) and progesterone receptor (PR) expression in uterine leiomyomas seen at LTH, Ogbomoso, over a five-year period using immunohistochemical techniques.Methods: This was a hospital-based retrospective study of histologically diagnosed leiomyomas in the histopathology department of a teaching hospital between January 2012 and December 2016. A total of 141 cases of uterine leiomyomas were semi-quantitatively analysed immunohistochemically for PR and BCL-2 antigens. Results: Immunohistochemical analysis showed that out of 141 cases studied, 74 (52.5%) and 118 (83.7%) were positive for BCL-2 and PR, respectively. Among the 141 cases, 23 (16.3%) were negative for both PR and BCL-2. There was a moderate positive correlation between the immunohistochemical expression of BCL-2 and PR antigens, with a p-value < 0.001 (Pearson correlation = 0.563). Conclusion: This study showed that the majority of women with leiomyomas expressed both progesterone receptor and B-cell lymphoma-2 antigens. Therefore, selective women with leiomyomas could benefit from progesterone receptor modulators instead of undergoing invasive procedures such as myomectomy or hysterectomy.

Karishma Karishma

Investigating students’ attitudes toward poverty and impoverished persons - a case study: ho chi minh city open university, data of vietnam

Efforts to understand the causes of poverty, how poverty is perceived have become important in the fight to mitigate poverty. In Vietnam, studies on the attitudes of poverty in specific populations, such as Vietnamese students, are rare. Thus, this dataset reports the results collected from 180 social work students and non-social work students of Ho Chi Minh City Open University through attitudes toward poverty and poor people in Vietnam. The Attitude toward Poverty Short Form 21-item scale, developed by Yun & Weaver, was used for the data collection. The survey results showed that when looking for causes of poverty, social work students and non-social work students put the most emphasis on structural factors of poverty. However, social work students, compared with non-social work students, consider personal deficiency and stigma more important. In future, this dataset can serve as a reference source for comparative studies on student’ attitudes toward poverty and impoverished persons and for social work education.

Le Minh Tien Le minh tien

Deprivation in education amidst covid-19 pandemic crisis

The education sector is one of the most affected areas by the pandemic. It caused a huge chasm that could affect the teaching-learning industry in the future. Although it is possible to have deprivation in education, the concept must not be embraced. Instead, HEI should focus on developing new and innovative ways of delivering education constructively. This paper focuses on the importance of both research and teaching in education. The two areas are identified and analyzed respectively to adopt innovative methodologies to enhance productivity in a higher learning institute. This paper intends to propose relevant teaching and learning methods to benefit the students, the university, and society. This paper utilizes several factors involved in the pandemic crisis and suggests ways to use several methods to regenerate the learning environment without hassle.

Santosh kumar Santosh kumar

Transforming pharmacy education and practice for the new century

Pharmacy education has evolved from the outdated changing 5 to 4 year dispensing pharmacy program that focus on the medicines value the compounding and dispensing to patient-oriented pharmacy program (Pharm D) that focus on patient, experiential learning (practicum courses), evidence -based program that does foster critical thinking, and clinical reasoning skills [1] and improving patient care.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Physical activity and physical literacy: the pharmacological benefits of exercise, a women’s perspective

The valuable effects of regular exercise for promotion of health and therapy of diseases were obviously evaluated. The notion that exercise can be considered as a medication has been hypothesized. The growing problems of obesity and non-communicable diseases have placed a great burden on public health experts to promote physical literacy and physical activity among the modern day population. Physical literacy and physical activity have become the cornerstones of women’s health. Women have certain special needs that includes reproductive health. Increased physical activity and maintaining normal body image and body weight will help a woman attain physical, mental and spiritual development. With the growing number of women with obesity and the implication of obesity as one of the main risk factors for non-communicable diseases like diabetes, hypertension, stroke and osteoarthritis, a knowledge and awareness about physical activity is essential. Thus, physical activity is a fundamental aspect of the improvement of motor skills and work performance, allowing a better healthy lifestyle. Physical exercise is effective to be measured as a drug, however, more care should be considered to the dosing and individual variations between genders.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

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