The study aims to explore the possible morphological features of monosodium urate monohydrate crystals. The study was carried out on a glass slide under a microscope to observe the growth patterns. As a result, three types of spherical ring-banded, dumbbell, and composite spherulites were observed. This study gives detailed information about the morphology and aggregation patterns of mono sodium urate monohydrate crystals.
Writing is a complex skill and is difficult for students to master well. This study aims to determine the effect of the application of Think Talk Write learning models with poster media on the writing skills of persuasion essay from fifth grade elementary school students. This type of research is a quasi-experimental design with a pre-test post-test control group. The sample in this study was VA and V class students of SDN Rambigundam 01 Jember. Collecting data in this study using interviews, tests, and documentation. The data analysis technique of student learning outcomes uses t-test. Based on the results of the t-test on the learning outcomes of students' persuasive essay writing skills, it is known that the value of tcount> ttable, (2.208> 2.0180), so it can be concluded that the hypothesis is accepted that the Think Talk Write learning model through poster media influences the writing skills of persuasion writing in the fifth grade students of SDN Rambigundam Jember 1. The results of the pretest and posttest activities also showed that the increase in the value of writing skills written by students in the experimental class was higher than the increase experienced by the control class. Difference in the increase in the average value experienced by the experimental class and control class by 3,7. Menulis merupakan salah satu keterampilan yang kompleks dan sulit dikuasai siswa dengan baik. Penelitian ini bertujuan untuk mengetahui pengaruh penerapan model pembelajaran Think Talk Writedengan media poster terhadap keterampilan menulis karangan persuasi siswa kelas V SD. Jenis penelitian ini merupakan eksperimen semu dengan desainpre-test post-test control group. Sampel dalam penelitian ini adalah siswa kelas VA dan V B SDN Rambigundam 01 Jember. Pengumpulan data dalam penelitian ini menggunakan metode wawancara, tes, dan dokumentasi. Teknik analisisdata hasil belajar siswa menggunakan uji t-test. Berdasarkan hasil uji-t terhadap hasil belajar keterampilan menulis karangan persuasif siswa, diketahui bahwa nilai thitung>ttabel, (2,208>2,0180), sehingga dapat disimpulkan bahwa hipotesis diterima yaitu model pembelajaran Think Talk Write melalui media poster berpengaruh terhadap keterampilan menulis karangan persuasi pada siswa kelas V SDN Rambigundam 01 Jember. Hasil kegiatan pretest dan posttest juga menunjukan bahwa peningkatan nilai keterampilan menulis karangan siswa di kelas eksperimen lebih tinggi dari pada peningkatan yang dialami kelas kontrol. Selisih peningkatan rata-rata nilai yang dialami kelas eksperimen dan kelas kontrol sebesar 3,7.
BACKGROUND AND OBJECTIVES: The requirements of stakeholders for the qualitative transformation of the approaches of industrial enterprises – environmental users to introduction of economic activities cause an increase in the role of environmental responsibility as their strategic priority for development. The purpose of the study is to improve the practical tools for calculating and developing strategies for the development of environmental responsibility of industrial enterprises. METHODS: In the study, tools for assessing the level of environmental initiative of an industrial enterprise as an integrated indicator of environmental initiative are suggested. It is expressed as the arithmetic mean of ten factors of environmentally proactive behavior of industrial enterprises. To achieve the objectives of the study, methods of criterion-qualitative assessment are suggested, such as expert assessment and survey. The assessment system includes ten factors rated on a 10-point scale and weighted by significance. The integrated indicator of the environmental initiative acquires values within, is a stimulant of environmental responsibility. FINDING: One justified a scientific and methodological approach to assessing the level of environmental responsibility or the industrial enterprise, including calculation of the corresponding taxonomic indicator with consideration of the quantitative factors of its environmental responsibility and the qualitative and quantitative factors of environmental initiative. This enables the possibility to assess the relevant state of environmental responsibility and determine the volumes for further correction of the ecological strategy for the development of the industrial enterprise. CONCLUSION: As a conclusion, practical recommendations are made for the implementation of organizational and economic support of environmental responsibility in the development strategy of an industrial enterprise taking into account the impact of its environmental initiative and environmental duty. The level of environmental responsibility of industrial enterprises taken into account when developing recommendations on adjustment of their environmental strategy of development is determined, which as a whole allowed to form organizational and economic support for environmental responsibility of the enterprises under study. Thus, an enterprise, which only ensures compliance with environmental emission standards (compensation strategy or sufficiency strategy) cannot be characterized by a high level of environmental responsibility. To ensure a high level of environmental responsibility, an industrial enterprise must rely on a proactive strategy or a strategy for sustainable use of nature.
Introduction/aims: Maturity-Onset Diabetes of the Young (MODY) is a monogenic non-autoimmune diabetes with 14 different genetic forms. MODY-related mutations are rarely found in the Tunisian population. Here, we explored MODY related genes sequences among seventeen unrelated Tunisian probands qualifying the MODY clinical criteria. Materials and methods: The GCK and HNF1A genes were systematically analyzed by direct sequencing in all probands. Then, clinical exome sequencing of 4,813 genes was performed on three unrelated patients. Among them, 130 genes have been reported to be involved in the regulation of glucose metabolism, β-cell development, differentiation and function. All identified variants were analyzed according to their frequencies in the GnomAD database and validated by direct sequencing. Results: We identified the previously reported GCK mutation (rs1085307455) in one patient. The clinical features of the MODY2 proband were similar to previous reports. In this study, we revealed rare and novel alterations in GCK (rs780806456) and ABCC8 (rs201499958) genes with uncertain significance. We also found two likely benign alterations in HNF1A (rs1800574) and KLF11 (rs35927125) genes with minor allele frequencies similar to those depicted in public databases. No pathogenic variants have been identified through clinical exome analysis. Conclusions: The most appropriate patients were selected, following a strict clinical screening approach, for genetic testing. However, the known MODY1-13 genes could not explain most of the Tunisian MODY cases, suggesting the involvement of unidentified genes in the majority of Tunisian affected families.
By January 2020, severe acute respiratory syndrome coronavirus-2 has spread internationally to a pandemic that mainly targets the respiratory system. The relevant infectious disease has been identified as coronavirus disease-2019 (COVID-19) by World Health Organization and declared as a global pandemic. In Libya, National Center for Disease Control reported the first case of coronavirus disease-2019 on 24th March, 2020. The authorities decided to close borders and activate designated treatment centers to deal with COVID-19 cases and contain the outbreak of SARS-COV-2. This study aimed to assess and evaluate the pharmaceutical situation of medications used in pharmacological management of hospitalized COVID-19 patients in Tripoli, Libya. Three WHO availability indicators were selected to be studied and reported. A comprehensive list of medicines used in the management of hospitalized COVID-19 patients was constructed after reviewing and comparing seven national and international pharmacological management protocols and guidelines for hospitalized COVID-19 patients. This comparison revealed that nearly 50 medications are intended for use in COVID-19 inpatient pharmacological management. They all agreed about the use of three medications, representing one from each main class. This list was used to cross check their availability at the chosen designated COVID-19 treatment center. This study proved that local treatment center’s protocol is more in line with international guidelines than the national treatment guideline. The later was issued on March 2020. The Libyan National Essential Medicines’ List contained 25 out of 50 medications of the comprehensive list based on the last update in April 2019. This study recommends that national treatment guidelines and National Essential Medicines’ list require updating. Not all medications used in COVID-19 inpatient management were available in local treatment centers, although, the Emergency Management Department of Ministry of Health in Libya is responsible for the supply of the required medical supplies and medications to the COVID-19 treatment centers.
Mediterranean journal of pharmacy and pharmaceutical sciences
This study investigates the access and equity challenges faced by tribal students in higher education institutions in Telangana, India. Despite various governmental initiatives aimed at improving educational outcomes for tribal communities, significant disparities persist. This research employs a comparative analysis across selected universities in Telangana, focusing on enrolment rates, retention, academic performance, and support services tailored for tribal students. Data is gathered through a combination of quantitative surveys and qualitative interviews with students, faculty, and administrators to gain a comprehensive understanding of the barriers and facilitators affecting tribal education. The findings reveal systemic inequities related to socio-economic status, cultural relevance of curricula, and the availability of financial and academic support. Moreover, the study highlights successful practices and policies implemented by certain institutions that promote inclusive education and enhance access for tribal students. The results underscore the need for targeted interventions to create a more equitable higher education landscape in Telangana, ultimately contributing to the empowerment of tribal communities and their representation in the academic sphere.
Analgesic activity on two Cleome scaposa and Cleome brachycarpa by applying pressure-induced pain model
Background: Allied health science students often experience elevated academic stress due to the demanding nature of their curricula, which blend theoretical instruction with clinical practice. Examination periods, in particular, exacerbate psychological pressure, potentially compromising academic performance and overall well-being. Physical activity (PA) has been widely recognized for its protective role against stress, yet limited research has been conducted specifically among allied health science students. This study examined the correlation between physical activity and perceived stress levels among undergraduate allied health students during examination periods at Desh Bhagat University. Methods: A descriptive cross-sectional correlational study was conducted over eight weeks, from October to November 2024. 250 undergraduate students were proportionately and randomly selected from the Nursing, Physiotherapy, Radiography, and Medical Laboratory Science departments. Data collection instruments included the International Physical Activity Questionnaire–Short Form (IPAQ-SF) and the Perceived Stress Scale (PSS-10). Descriptive statistics, Pearson’s correlation, and one-way ANOVA were performed using SPSS version 25 to analyze the data. Results: Out of 250 questionnaires distributed, 237 were deemed valid for analysis. Among the respondents, 40.9% reported low physical activity, 38.4% moderate, and 20.7% high. In terms of stress levels, 65.4% experienced moderate stress, and 19.4% reported high stress. A statistically significant negative correlation was observed between physical activity and perceived stress (r = -0.42, p < 0.001). Furthermore, one-way ANOVA revealed that students with higher physical activity levels had significantly lower stress scores (F = 18.93, p < 0.001). Conclusion: Physical activity is an effective non-pharmacological strategy for mitigating academic stress among allied health science students. The results highlight the importance of promoting regular physical activity, particularly during high-stress academic periods, as a means of enhancing mental well-being and academic success.
In these researched analyses of different forging product for controlling the forging waste in forging process. In forging process forging waste are carry with forging operation which identify by parting line of products. Parting which defines the product upper and lower die meshing area. Those extra material are used in forging operation which goes to out side of die that material is called as waste of forging. The foraging waste are not use for further any product manufacturing process for their hardness. There for such waste are to controlled for increasing the product utilization any minimising the production cost. In that paper we concentrate to minimizing waste of forging by amylases of different products.
Physically unclonable function (PUF) is a hardware security module preferred for hardware feature based random number and secret key generation. Security of a cryptographic system relies on the quality of the challenge-response pair, it is necessary that the key generation mechanism must unpredictable and its response should constant under different operating condition. Metastable state in CMOS latch is undesirable since it response becomes unpredictable, this feature used in this work to generate a unique response. A feedback mechanism is developed which forces the latch into the metastable region; after metastable state, latch settle to high or state depends on circuit internal condition and noise which cannot be predicted. Obtained inter hamming variation for 8 PUF is 51% and average intra hamming distance is 99.76% with supply voltage variation and 96.22% with temperature variation.
Therapies highly plays a crucial role for all those children and adults with disabilities. In this article, We aim to research the Special Educators’ Knowledge about Therapies in various special schools in the city of Hyderabad, Telangana, India. A qualitative approach was taken for this purpose. Questionnaires was used to collect the data. It was found that the teachers did not have proper conception on Therapies. The data indicated that the teachers are unaware about the unconventional therapies such as Drama Therapy, Pet Therapy and Laughter Therapy and there benefits when working with CSN. This lack of awareness needs to be addressed for the enhancement of the teacher as well students capabilities.
This abstract provides an overview of the critical role of academic leadership and governance in higher education institutions. As the landscape of higher education undergoes profound transformations, academic leaders and governance structures play a pivotal role in shaping the direction, quality, and effectiveness of educational institutions. This abstract highlights key themes, challenges, and considerations related to academic leadership and governance, emphasizing the need for adaptability, transparency, and inclusivity in the decision-making processes. The abstract begins by acknowledging the evolving nature of higher education and the increasing complexity of issues facing institutions, including technological advancements, changing student demographics, and shifting funding models. It underscores the central importance of academic leadership and governance in addressing these challenges and promoting institutional excellence.
Bhaishajya kalpana is an art and science of preparing and dispencing medicine. Guggulu is a Niryasa (oily latex) achieved from small tree called Indian bedellium. Botanical name is commiphora mukul. Guggulu is an amorphous, translucent, solid adhesive, oleo-gum resin is produced by the process of gummosis from its plant. Many other Ayurvedic classics have mentioned various formulations of Guggulu for the treatment of various ailments. Bhashajya ratnawali followed various kalpana use for formuations. Guggulu kalpana is secondary formulations of bhaishajya kalpana. . Guggulu is one among the best binding agents and its used as single or compound drug in the form of pills, Formulations which contains Guggulu as main ingredient, they can be called as Guggulu kalpana. Here in Bhaishajya Ratnawali, Guggulu is used in yoga for both purposes, as a base and as well as medicament also.In bhaishajya Ratnavali Guggulu when modified into different formulations. It can also be used in many diseases along with different combinations of drugs with their anupana, Guggulu kalpana beneficial in treating many diseases. The Guggulu Kalpana is indicated in almost all the strotovikaras and also a number of research works have been proved the wide range of action of Guggulu .
The purpose of this research was to examine the mediating effect of empowerment on the linkage between Total Quality Management (TQM) and service recovery performance in the hotel industry. Although much has been written about TQM, empowerment and service recovery performance, but the role of empowerment as a mediator in the relationship between TQM and service recovery performance has remained a relatively unexplored research area. A 93-item questionnaire is designed to measure TQM, empowerment and service recovery amongst employees in five-star hotels in Jordan, and 254 usable questionnaires were used in this study. Principal components analysis determined the factor structure and regression analysis determined the relationships between the study’s variables. The results revealed that the TQM implementations have positive effects on empowerment and service recovery performance. Moreover, the study found the full mediating effect of empowerment in the relationship between TQM and service recovery performance. Implications, limitations and future research are discussed at the end. This study proposes model of influence of TQM in service recovery performance, whereby empowerment fully mediates this relationship.
Computer as a revolution left no area of life untouched in the present world. It is of tremendous help in all field of life. Hence, the knowledge of computer is a necessity for existence of everybody in this global village. The invention of computer has transformed our simple manual works to sophisticated life of automated works to meet the global demand for the higher productivity and increased efficiency with high precision. Computer is increasingly becoming compulsory in nearly all fields of studies, not because of anything but its accuracy and versatility in processing data. Many tasks at home or office are being automated rapidly with computer. Thus it is becoming apparent that in whatever discipline or working sector, the computer is now a very vital tool for efficiency improvement and precision of job or task execution. This is designed to meet the prerequisite need of everybody that are interested and wish to know about computers science and computing in general. A computer is an electronic device, operating under the control of instructions stored in its own memory. These instructions tell the achine what to do. The computer is capable of accepting data (input), processing data arithmetically and logically, producing output from the processing, and storing the results for future use. Most computers that sit on a desktop are called Personal Computers (PCs). The "computer" is an ensemble of different machines that you will be using to get your job done. A computer is primarily made of the Central Processing Unit (usually referred to as the computer), the monitor, the keyboard, and the mouse. Other pieces of hardware are commonly referred to as peripherals. In everyday life activities, we process data or encounter cases of data processing. A typical example of data processing is the generation of statement of student result from the marks score in an examination and continuous assessment. It is essential to know that information is as good as the data from which it is derived, and the transformation process which they are subjected to. Meaningless data or inappropriate processing produces wrong information. Thus computer gives you results corresponding to what data you supply and how you process it (i.e. ëgabbage- in, gabbage-outí) Summarily, the intelligent performance of a computer depends on correctness of input data and the intelligence performance of the human being that drives it.
Rice bean (Vigna Umbellata), a traditional crop cultivated across South, Southeast, and East Asia, is characterized by its wild variety spanning the tropical monsoon forest climatic zone. Despite its vast nutritional and production potential, falling within the leguminous family Fabaceae, the rice bean represents one of many underutilized crops. Indigenous to South and Southeast Asian regions, particularly hilly areas, rice bean is cultivated alongside crops like maize, forming an integral part of impoverished farming communities' livelihoods. Despite its extensive utilization in traditional practices, its commercial significance remains largely unrecognized. However, recent attention has been drawn to the rice bean's nutritional richness, bioactive compounds, and various medicinal properties, including anti-inflammatory, antioxidant, and antidiabetic effects. This significant attention underscores its potential for commercialization and contribution to improving the livelihoods of underprivileged populations. Furthermore, its cultivation and processing give rise to diverse products, reflecting its cultural significance and adaptability across different regions.
Strain improvement studies were conducted for the production of L-asparaginase from a marine fungus Beauveriabassiana SS18/14 by employing physical and chemical mutagens, in a systemic manner to obtain mutants that have higher L-asparaginase production. The wild strain produced 6.32 IU/mL of L-asparaginase activity while the UV mutant UVF-4 yielded 8.34 IU/mL and nitrous acid mutant UVF4-N-2 exhibited 10.44 IU/mL enzyme activity. The overall strain improvement programme increased L-asparaginase activity 1.65 times with respect to the parent wild strain.
A huge number of embedded devices offer their services to the end users in pervasive environments. Context-aware discovery is a rich and very dynamic system extensively applied for combining the different mobile devices, sensors, actuators and software functions. Existing knowledge-based system using the Common KADS (CKADS) system represent contextual information but algorithm are not effective in predicting the user behavior. Current Location-aware Private Service Discovery (LPSD) considers the discovery path for reducing the distributed topology and flooding operations. LPSD in pervasive environment is not effective in accurately locating the required service by searching method. To present an architecture principle for accurately predicting the user behavior in mobile-pervasive computing environment, Affluent Context Aware Systems based on the User Behavior (ACAS-UB) is proposed in this paper. ACAS-UB mechanism contains the class of mobile devices that can sense (i.e.,) search the physical pervasive environment. Affluent means effectively engaged mobile devices in ACAS-UB mechanism which uses the context information. The ACAS-UB context information contains the judgment of the similar users and also the response from the other users for improving the effectiveness in pervasive environment user behavior prediction. Master-slave concept is used in the ACAS-UB mechanism for the easy collection of response information from the different users. ACAS-UB mechanism construct the user profile initially from the context information, then performs the similarity measure and finally work is to predict the user behavior. ACAS-UB mechanism provides the hints which are necessary to explore different options, rather than just limiting the options in mobile-pervasive computing environment. ACASUB mechanism is experimented on the factors such as message overhead in pervasive environment, scalability and approximately 10 % lesser processing time.
Ensuring consistent raw material quality is a significant challenge in chemical manufacturing, particularly for medicinal compounds where safety and efficacy are paramount. In these situations, a unique methodology known as Statistical Process Control (SPC) come into play. This study provides statistical process control analysis of four critical operational parameters for most the raw chemical compounds, especially in the medicinal chemistry— Specific Optical Rotation (SOR), Water Content (WC), RI, and Chromatographic Purity (CP)—derived from a dataset of 26 observations in an applied engineering context. The methodology encompasses descriptive statistics, rigorous distribution identification using Goodness-of-Fit tests, and process stability assessment via Individual- Moving Range (I-MR) and Exponentially Weighted Moving Average (EWMA) control charts. Descriptive statistics revealed diverse data characteristics, notably the high positive skewness (2.623) and kurtosis (9.386) of WC (Mean ± Standard Deviation: 0.177±0.106987) and the presence of negative values for SOR (Mean: -0.1, Min: -2, Max: 2). Distribution fitting identified Logistic and Normal as the most suitable for SOR, while RI demonstrated a best fit for normal distribution with Johnson Transformation. WC and CP exhibited significant non-normality and challenges in fitting standard distributions, often accompanied by warnings regarding convergence or parameter estimation stability. Crucially, control chart analysis identified significant out-of-control conditions for SOR, WC, and RI, indicating inherent process instability. CP, conversely, demonstrated stability with the optimized EWMA chart. The findings underscore the necessity of tailored statistical approaches for diverse data characteristics in quality control. Implementation of Statistical Process Control should not be underestimated in the chemical manufacturing industry, notably in the developing nations.
Background: Old age is one of the vulnerable and prone stages in terms of health status. So this study aimed to assess the nutritional status and common health complications of older people. Methods: Simplified Nutritional Appetite Questionnaire (SNAQ), Anthropometric measurements, Diet History Method, and Mini Nutritional Assessment (MNA) tools were used to measure the nutritional status. Data were analyzed by using Statistical Package for Social Science (SPSS) version 16. Results: Out of the total 320 elderly participants the mean SD value for the age of male and female was 67.25 6.5 and 67.32 7.7 years respectively. According to BMI classification, it was noticed that with advancing age the percentage of underweight was also increased such as for 60–75 years old age group the underweight percentage was 30.0% where for 76 to 85 and >85 years old age group the underweight percentage was 45.0% and 60.0% respectively. According to the MNA score, 97 elderly respondents were malnourished and a total of 172 respondents had SNAQ scores below 14. This study found a statistically significant (P < 0.05) correlations among various health complications with nutritional status according to MNA score. In addition 56.6% (OR ¼ 1.24, 95% CI ¼ .799–1.939), 63.8% (OR ¼ 1.18, 95% CI ¼ .745–1.857) and 64.7% (OR ¼ 1.14, 95% CI ¼ .720–1.804) respondents had diabetes mellitus, hypertension and cardiovascular disease respectively. The risk of musculoskeletal pain (OR ¼ 1.073, 95% CI ¼ .684–1.681), bedsore (OR ¼ 1.884, 95% CI ¼ .903–3.934) and decreased sense of thirst (OR ¼ 1.278, 95% CI ¼ .821–1.991) were higher among females than males. A little number of the elderly used to take milk, meat, and fish daily. Conclusion: During this cross-sectional study, significant correlations among nutritional changes with health complications were determined. To prevent malnutrition among the elderly a proper health policy as well as periodical nutritional screening should be conducted
Université Nazi Boni
Central Council For Research In Unani Medicine, Ministry Of Ayush, Government Of India, New Delhi