Urolithiasis is a common worldwide problem with high recurrence. This review covers Convolvulaceae seven (07), Costaceae four (04), Ebenaceae four (04), Fagaceae six (06), Hypericaceae eight (08), Lauraceae nine (09), Liliaceae twelve (12) and Lythraceae three (03) plants used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. salman ahmed

Scholars who apply artificial intelligence to political questions seek, most generally, to expand the scope and relevance of political model analysis. By incorporating the effects of variable human notions, traditions, and meanings, they seek to humanize political models. Most early applications of artificial intelligence in political science research address substantive issues pertaining to political decision making. Most of these works apply production-system technology to construct choice models in for eign-policy decision contexts. In recent years, political applications have begun to diver sify. Today, lively research efforts flourish in widely varied application areas, such as computational text analysis, logic programming, computer learning, and conflict sim ulation. The works reviewed here constitute the early steps of a nascent program of study. Much remains to be accomplished. Nevertheless, the efforts conducted thus far suggest many potentially fruitful research avenues. Youth are the most essential and promising segment of every country’s population. India has a larger advantage over other countries in terms of becoming a global leader because we effectively tap into the youth’s potential. Quality education is the only way to achieve this. With artificial intelligence’s potential growth in India, now is the ideal time to incorporate AI in education to reap its benefits and prepare India’s young for the future. Artificial intelligence has great potential in India. India’s AI technology has the potential to make it a world leader in artificial intelligence. In India, AI technology is used effectively in nearly every area, including agriculture, healthcare, education, infrastructure, transportation, retail, manufacturing, and

Dr gedam kamalakar

Neuroblastoma is the most prevalent extracranial solid tumor in pediatric patients, originating from sympathetic nervous system cells. Metastasis can be observed in approximately 70% of individuals after diagnosis, and the prognosis is poor. The current care methods used, which include surgical removal as well as radio and chemotherapy, are largely unsuccessful, with high mortality and relapse rates. Therefore, attempts have been made to incorporate natural compounds as new alternative treatments. Marine cyanobacteria are a vital source of physiologically active metabolites, which have recently received attention owing to their anticancer potential. This review addresses cyanobacterial peptides' anticancer efficacy against neuroblastoma. Numerous prospective studies have been carried out with marine peptides for pharmaceutical development, including research on anticancer potential. Marine peptides possess several advantages over proteins or antibodies, including small size, simple manufacturing, cell membrane crossing capabilities, minimal drug-drug interactions, minimal changes in blood-brain barrier (BBB) integrity, selective targeting, chemical and biological diversities, and effects on liver and kidney functions. We discussed the significance of cyanobacterial peptides in generating cytotoxic effects and their potential to prevent cancer cell proliferation via apoptosis, the activation of caspases, cell cycle arrest, sodium channel blocking, autophagy, and anti-metastasis behavior.

Dr. salman ahmed

This study outlines the different kinds of information resources available, the current situation of digital preservation, the requests of librarians and users, and offers recommendations, although limited, for future research on storage mediums, transfers, conversions, and general management techniques. Libraries worldwide have had to address a number of concerns related to digital information preservation, including organizational, resource, legal, and technical ones. Despite the fact that libraries have been exploring a variety of preservation techniques, including emulation, migration, and technology preservation, there is still a need for a preservation approach that is both financially realistic and widely accepted. Digital content access is ensured over time through a combination of rules, strategies, and actions known as digital preservation. An information resource is any component of a computer system that is only partially available; an electronic resource is information that can be stored as electrical signals; and a web resource is a data source that is accessible over the World Wide Web. It is important to preserve information of long-term value so that future generations can access it. This is the goal of information source preservation. Formal preservation programs have been launched for conventional resources in document, microform, photographic, and, to a lesser extent, audio-visual formats by numerous large libraries, information centers, and archives in recent decades. The field of digital preservation is still quite experimental and fraught with the dangers of using unproven techniques. The introduction of digital preservation adds to the challenge facing documents and library services in maintaining a legacy of documents in traditional formats.

Dr. awadhesh singh gautam

Argostemma quarantena, a new rubiaceous species from Vagamon Hills of southern Western Ghats, India is described and illustrated here. The species shows similarities with two south Indian endemics, A. anupama and A. courtallense, but differs in many qualitative attributes. The present status of genus Argostemma in India is briefly discussed. An artificial key for the identification of Argostemma in Western Ghats is also provided.

Dr. anoop balan

Corporate social responsibility (CSR) is a self-regulating business model that helps a company be socially accountable—to itself, its stakeholders, and the public. Reliance Foundation (RF) is a not-for-profit organization established by RIL to bring about changes in Indian society seamlessly. CSR is for the community, it is equally valuable for a company. CSR activities can help forge a stronger bond between employees and corporations, boost morale and help both employees and employers feel more connected with the world.

Vidya bhat

Introduction: Augmented Reality (AR) technology is increasingly recognized for its potential to enhance various aspects of dental practice, including treatment planning, patient education, and training. Despite this potential, the understanding of dental professionals' knowledge, attitudes, and practices regarding AR technology remains underexplored. The objective of this research is to examine the experience, perceived advantages, and real application of augmented reality (AR) Technologies of dental faculty and students. Methodology: A sample of 132 dental students, some integrated into the workforce as part-time private dentists, and faculty members of a single dental school, completed a self-administered online survey. Knowledge and application of AR technology in dentistry, and Experience with AR practice, were the constructs of the study. An administered questionnaire, partially digital and partially paper and pencil, was divided into two parts: Knowledge Assessment and Practice Assessment. The survey results were analyzed using reference statistics. Results: Knowledge Assessment respondents confirmed understanding Augmented Reality (AR) technology (69.7), and AR technology in dental training/education was recognized (65.9). 57.6% of the participants in the Practice Assessment declared absence of AR in their educational and/or professional practice, but an AR technology practice was wanted (67.4). The self-rated proficiencies that 44.47% of the respondents professed were in the range of self-score 3 in the application of AR (moderate). A small fraction (16.7) declared their AR application self-score was above the higher order. Conclusion: It can be concluded from this work that AR technology in academic and practical dentistry is vastly underutilized, notwithstanding the high realization and appreciation for its application.

Oral sphere journal of dental and health sciences

Background and Objective: Health care workers (HCWs) are at the highest risk of contracting COVID-19, so their knowledge about the disease and their preventive attitude and practice toward COVID-19 are of concern. The present study aimed to assess the knowledge, attitudes, and practices of HCWs toward COVID-19 in Al-Thawra Hospital, Ibb Governorate, Yemen. Materials and Methods: We conducted a cross-sectional survey among HCWs in Al-Thawra Hospital, Ibb, Yemen, from January 1 to March 31, 2022. Results: Of the 80 participants, 50 (62.5%) were males and 30 (37.5%) were females with a mean age of 29.33±7.86 years. About 51.2% of respondents were aware that sneezing is a recognized symptom of COVID-19, while most were unaware of the extrarespiratory symptoms of the disease, such as diarrhea and confusion. About 28.7% of respondents believed that eating or contacting wild animals would result in infection by the COVID-19 virus, with the majority (71.3%) agreeing that wearing a well-fitting face mask effectively prevents COVID-19 infection. Approximately 48 respondents (60.0%) believed that washing hands could prevent contracting COVID-19, and only 31 (38.7%) agreed that if a patient shows signs and symptoms of COVID-19, they can confidently participate in that patient’s treatment. In response to avoid COVID-19, about 23 respondents (28.7%) had always gone to crowded places, and 35 (43.6%) had always worn face masks at every contact with patients, while only 14 (17.5%) of participants refrained from shaking hands and 37 (46.3%) always washed their hands before and after handling each patient. Conclusion: This study showed that most respondents have poor knowledge regarding the clinical picture of COVID-19 and its mode of transmission as most of them failed to detect an extrapulmonary manifestation of COVID-19 and were unaware of the possibility of transmission of the disease from wildlife. In addition, the attitude and preventive practice of the respondents were unsatisfactory in containing the transmission of the disease.

Karishma

Background: Information on Bleomycin pulmonary toxicity (BPT) in Qatar is scarce. The aim of this study was to estimate the prevalence of BPT and to describe its clinical significance and outcome in germ cell tumor (GCT) patients who received bleomycin-containing regimens.Methods: This retrospective cross-sectional study was conducted at the National Center for Cancer Care and Research. It included all patients diagnosed with GCT and treated with a bleomycin-containing regimen between January 2002 and December 2008 Results: We identified fourteen patients with GCT who received bleomycin containing regimen. Four of them (28.5%) had developed BPT, and they were males with mean age of 39.3±8.3 years (range: 25-46 years). The calculated creatinine clearance before treatment was normal in the 4 cases. Evaluation of the chest computed tomography scan before starting bleomycin containing regimens revealed that none of our patients had pre-existing parenchymal lung disease. The mean cumulative bleomycin dose was 187.5± 153.7 U, while the mean time to onset of BPT was 3.5±2.1 months. Once the diagnosis of BPT was established, bleomycin was discontinued in the four patients and short courses of dexamethasone were administered. Two patients (50%) died, while one patient survived with a fibrosis sequel, and the fourth patient recovered without a fibrosis sequel. Conclusion: BPT is one of the life-threatening side effects of this drug that every doctor should be aware of when treating GCT, therefore, a high index of suspicious is needed for early recognition of BPTs.

Karishma

Anti-emetic activity Of four aromatic medicinal plants (Curcuma caesia Roxb., Piper longum Linn., Piper nigrum Linn., and Syzygiunt aromaticum (Linn.) Merr. & Perry) was studied in chicks. The ethanol extracts of these plants were administered at 150 mg/kg BW orally. All the extracts showed a significant (P < 0.05) decrease in retches induced by copper sulphate pentahydrate given orally at 50 mg /kg BW. Domperidone was given at 100 mg/kg as a reference drug.

Dr. salman ahmed

Here is presented a short review on the medical potency of the most toxic plant of Europe. In many countries it isn't concerned any more as therapeutic agent in medicine due to frequent intoxications. However, in the homeopathy, preparations and patent medicines still contain aconitine and other alkaloids (abundant levels). There exists even a US Patent "ACONITINE COMPOUNDS, COMPOSITIONS, USES, AND PREPARATION THEREOF" (No. US 9,085,536 B2 by du Bois et al. 2015).

Stefan dahl

Several intricate interactions of environmental and genetic factors can lead to autoimmune conditions in susceptible hosts. Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease which can be triggered or exacerbated by infection or infectious reactions. The causal link between infections and autoimmunity has been established through clinical studies. Although several viral infections have been associated with SLE, yet the impact of COVID-19 on SLE onset and flares has not been well established. We report a young female who developed new-onset SLE shortly after having COVID-19 infection. Her clinical and lab parameters were highly suggestive of SLE and she responded to standard medical therapy. We also briefly discuss the pathogenetic mechanisms of autoimmunity in cases of viral infections.

Karishma

Stakeholder plays significant roles in project success. They ensure clear communication of project goals, contribute to decision-making, and demonstrate commitment, increasing the likelihood of successful outcomes. They also act as advocates within their organizations, generating buy-in and support. The main purpose of this paper is to identify and discuss the roles of shareholders in a project success. The paper is conceptual in nature and uses a number literatures ranging from 2007 to 2023 from a good number of journals. After scrutinized the literature review, the paper concludes a number of findings. The findings implies that stakeholders in a project is crucial for its success and sustainability. Stakeholders play a significant role in ensuring the performance of the project. Project managers need to acquire stakeholder management skills to address the communication requirements of stakeholders. This is important for the success of the project. The paper recommend that policymakers, practitioners and academia have to ensure the expectations and make a balance among the stakeholders.

Nazim ullah

Background: Poverty and malnutrition are associated with the risk of developing tuberculosis (TB). Nutritional reintegration with anti-TB therapy may improve treatment success rate. Aim: To investigate the nutritional status of low-income pulmonary TB patients in relation to the different anti-TB treatment phases. Methods: Forty five pulmonary TB patients and 40 controls aged 19-54 years, receiving treatment at Infectious Disease Hospital, Calabar, Nigeria, between September 2018 and July 2019 were studied. Serum total protein, albumin, iron and vitamin A were determined by colorimetric and HPLC methods respectively. Height and weight were measured and BMI computed, and data analysed using Student’s t-test, ANOVA, and Pearson’s correlation at P<0 P=0.001).>0.05) respectively. Albumin and iron were significantly lower in CPAT-HIV compared with CPAT patients. Albumin correlated positively and significantly with iron (r=0.405, p=0.006) in TB patients. Conclusion: Tuberculosis is associated with decreased BMI, albumin, iron and vitamin A, and higher total protein, and globulin, suggesting that malnutrition may be associated with TB risk, poor treatment compliance and outcomes

Eworo raymond

Cancer is one of the most extreme medical conditions in both developing and developed countries around the world, causing millions of deaths each year. Chemotherapy and radiotherapy are critical treatment approaches, but both have numerous adverse health effects. Furthermore, the resistance of cancerous cells to anticancer medication leads to treatment failure. The rising burden of cancer overall requires novel, efficacious treatment modalities. Natural medications offer feasible alternative options against malignancy in contrast to western medicines. Furanocoumarins’ defensive and restorative impacts have been observed in leukemia, glioma, breast, lung, renal, liver, colon, cervical, ovarian, and prostate malignancies. Experimental findings have shown that furanocoumarins activate multiple signalling pathways, leading to apoptosis, autophagy, antioxidant, antimetastatic, and cell cycle arrest in malignant cells. Additionally, furanocoumarins have been shown to have chemopreventive and chemotherapeutic synergistic potential when used in combination with other anticancer drugs. Here, we address different pathways which are activated by furanocoumarins and their therapeutic efficacy in various tumors. Ideally, this review will trigger interest in furanocoumarins and their potential efficacy and safety as cancer-lessening agents.

Dr. salman ahmed

Communication is not always direct; it often involves nuanced elements like humor, irony, and sarcasm. This study introduces a novel two-level approach for sarcasm detection, leveraging Convolutional Neural Networks (CNNs). Convolutional neural networks (CNNs) are crucial for many deep learning applications, yet their deployment on IoT devices is challenged by resource constraints and the need for low latency, particularly in on-device training. Traditional methods of deploying large CNN models on these devices often lead to suboptimal performance and increased energy consumption. To address this, our paper proposes an energy-efficient CNN design by optimising batch normalisation operations. Batch normalisation is vital for deep learning, aiding in faster convergence and stabilising gradient flow, but there has been limited research on creating energy-efficient and lightweight CNNs with optimised batch normalisation. This study proposes a 3R (reduce, reuse, recycle) optimisation technique for batch normalization. This technique introduces an energy-efficient CNN architecture. We investigate the use of batch normalization optimization to streamline memory usage and computational complexity, aiming to uphold or improve model performance on CPU-based systems. Additionally, we evaluate its effectiveness across diverse datasets, focusing on energy efficiency and adaptability in different settings. Furthermore, we analyze how batch normalization influences the performance and effectiveness of activation functions and pooling layers in neural network designs. Our results highlight batch normalization's ability to enhance computational efficiency, particularly on devices with limited resources.

Jiby mariya jose

This study analyzed the performance of hybrid ORC -Stirling systems in terms of thermal-mechanical energy conversion in relation to small-scale power generation by industries in Delta state, Nigeria. The two main parameters examined included the thermal collection efficiency of evacuated tube collectors and the influence of the environmental parameters on the stability of torque and the power output of the shaft. The data collection was performed on solar irradiance, ambient temperature, wind speed and PCM thermal cycling at 8-hour intervals in 90 days, and analyzed by means of MATLAB-simulated multidimensional plots. Findings showed that evacuated tube collection produced efficiency of ≥65% thermal collection efficiency, providing sufficient heat input for ORC–Stirling systems to maintain torque deviations within ±5% and conversion efficiency ≥40%. Mean solar irradiance of 775W/m²and PCM cycling between 250–310°C supported continuous 8-hour daily operation of industrial machinery. The results showed that hybrid ORC-Stirling systems are reliable to drive small-scale industrial processes even when environmental conditions vary. It was therefore advised that the small-scale operators should invest in ORC-Stirling systems, the Manufacturer Association of Nigeria (Delta State Chapter) should create awareness and demonstrations of this hybrid ORC-Stirling system and tertiary institutions in Delta state should engage the faculties of Mechanical Engineering to conduct training and pilot projects to facilitate adoption and proper maintenance of this ORC-Stirling system. Such measures will further improve operational stability, cut down-time and sustainability and decentralized industrial power

Fxintegrity publishing

Strain improvement studies were conducted for the production of L-asparaginase from a marine fungus Beauveriabassiana SS18/14 by employing physical and chemical mutagens, in a systemic manner to obtain mutants that have higher L-asparaginase production. The wild strain produced 6.32 IU/mL of L-asparaginase activity while the UV mutant UVF-4 yielded 8.34 IU/mL and nitrous acid mutant UVF4-N-2 exhibited 10.44 IU/mL enzyme activity. The overall strain improvement programme increased L-asparaginase activity 1.65 times with respect to the parent wild strain

Dr.p.v.kamala kumari

Le discours du nouveau Président algérien, Monsieur Abdelmadjid Tebboune, se caractérise par une rhétorique différente de celle de ses prédécesseurs. Notre entreprise, dans le présent article, vise à rendre compte de cette spécificité discursive en interrogeant trois expressions ponctuant souvent son discours. Notre analyse se propose d’examiner des segments de discours collationnés à partir des différents entretiens périodiques accordés aux médias nationaux et internationaux ainsi que des allocutions du président lors des travaux réunissant le gouvernement et les walis. En guise de conclusion, nous déterminerons les motivations du choix de ces formules dans le discours présidentiel.

Assanvo

Pyrazole is a nitrogen containing 5-membered heterocyclic compound containing 3 carbons& 2 nitrogen atoms in the adjacent position of ring structure and is chemically known as 1, 2- diazole. Pyrazole nucleus is present in many pharmaceutically important compounds and intermediates . Majority of anti-inflammatory agents currently employed have GI irritation and enhanced acidity as side effects. As part of our efforts to develop newer and effective anti-inflammatory agents , ten newer pyrazole carbaldehydes were synthesized and evaluated for their anti-inflammatory activity using Diclofenac was the standard. Out of ten compounds synthesized, all compounds exhibited comparable activity with that of the standard.Highest percentage of haemolysis was observed for Pyrazole carbaldehydes with methoxy phenyl groups as substituents. These compounds should be considered for developing as leads for newer & safer anti-inflammatory agents.

Vinod b